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Journal Articles Current Opinion in Microbiology Year : 2002

Functional and evolutionary analysis of a eukaryotic parasitic genome

Abstract

The DNA sequences of the 11 linear chromosomes of the ∼2.9 Mbp genome of Encephalitozoon cuniculi, an obligate intracellular parasite of mammals, include ∼2000 putative protein-coding genes. The compactness of this genome is associated with the length reduction of various genes. Essential functions are dependent on a minimal set of genes. Phylogenetic analysis supports the hypotheses that microsporidia are related to fungi and have retained a mitochondrion-derived organelle, the mitosome.

Dates and versions

hal-00427309 , version 1 (28-10-2009)

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Christian Vivarès, Manolo Gouy, F. Thomarat, G. Metenier. Functional and evolutionary analysis of a eukaryotic parasitic genome. Current Opinion in Microbiology, 2002, 5, pp.499-505. ⟨10.1016/S1369-5274(02)00356-9⟩. ⟨hal-00427309⟩
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