Fatigue crack growth testswere performed under various mixed-mode loading paths, on maraging steel. The effective loading paths were computed by finite element simulations, in which asperity-induced crack closure and friction were modelled. Application of fatigue criteria for tension or shear-dominated failure after elastic–plastic computations of stresses and strains, ahead of the crack tip, yielded predictions of the crack paths, assuming that the crack would propagate in the direction which maximises its growth rate. This approach appears successful in most cases considered herein.