Synthesis of an X-ray opaque biodegradable copolyester by chemical modification of poly (epsilon-caprolactone). - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Biomaterials Année : 2006

Synthesis of an X-ray opaque biodegradable copolyester by chemical modification of poly (epsilon-caprolactone).

Résumé

Poly (epsilon-caprolactone-co-alpha-iodo-epsilon-caprolactone) was synthesized by binding iodine to PCL chain bearing carbanionic site on alpha-position of carbonyl groups using lithium diisopropylamide. Copolyesters containing from 10% to 25% of iodo-units were thus obtained. Viscoelastic properties (modulus, loss angle), thermal properties (T(m), T(c), DeltaH(m)), crystallinity and in vitro degradability of this new type of copolymers were measured. Their opacity to X-rays was assessed, and appeared high enough to be of interest for biomedical applications.

Domaines

Biomatériaux
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hal-00416779 , version 1 (11-01-2024)

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Paternité - Pas d'utilisation commerciale - Pas de modification

Identifiants

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Benjamin Nottelet, Jean Coudane, Michel Vert. Synthesis of an X-ray opaque biodegradable copolyester by chemical modification of poly (epsilon-caprolactone).. Biomaterials, 2006, 27 (28), pp.4948-54. ⟨10.1016/j.biomaterials.2006.05.032⟩. ⟨hal-00416779⟩
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