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Chapitre D'ouvrage Année : 2006

Multifunctional Polyester-Based Materials with Controlled Degradability

Estelle Renard
Valérie Langlois
Géraldine Rohman
  • Fonction : Auteur
Laurianne Timbart
  • Fonction : Auteur
Philippe Guérin

Résumé

Hydrolytic degradability can be fine-tuned in polyester-based materials by controlling the nature and placement of comonomers introduced within the polymer structures. This contribution describes how D,L-lactide-, ε-caprolactone-, and β-hydroxyoctanoate-containing polyesters can be used to design nanostructured drug delivery vehicles and mesoporous polymeric materials. In the first part, the efficient synthesis of poly(β-hydroxyoctanoate)-based block and graft copolymers is addressed. A versatile and straightforward approach toward mesoporous functional polymers via the partial hydrolysis of poly(D,L-lactide)-based Interpenetrating Polymer Networks (IPNs) is discussed in a second part.
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Dates et versions

hal-00416504 , version 1 (14-09-2009)

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Citer

Daniel Grande, Estelle Renard, Valérie Langlois, Géraldine Rohman, Laurianne Timbart, et al.. Multifunctional Polyester-Based Materials with Controlled Degradability. Scholz C., Khemani K. Degradable Polymers and Materials - Principles and Practice, American Chemical Society, pp.140-155, 2006, ACS Symposium Series, 9780841239722. ⟨10.1021/bk-2006-0939.ch009⟩. ⟨hal-00416504⟩

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