Article Dans Une Revue ChemMedChem Année : 2009

Induction of a melanoma-specific antibody response by a monovalent, but not a divalent, synthetic GM2 neoglycopeptide

Résumé

Human tumor cell-specific antibodies were induced in mice after immunization with a synthetic glycopeptide, which is based on the GM2 ganglioside carbohydrate moiety produced on a gram scale in bacteria. Such neoglycopeptides represent a promising cancer vaccine strategy for active immunotherapy targeting carbohydrates.

Fichier non déposé

Dates et versions

hal-00396633 , version 1 (18-06-2009)

Identifiants

Citer

S. Bay, S. Fort, L. Birikaki, C. Ganneau, E. Samain, et al.. Induction of a melanoma-specific antibody response by a monovalent, but not a divalent, synthetic GM2 neoglycopeptide. ChemMedChem, 2009, 4 (4), pp.582-587. ⟨10.1002/cmdc.200900032⟩. ⟨hal-00396633⟩
162 Consultations
0 Téléchargements

Altmetric

Partager

  • More