Croix-Rousse hospital launched a variety of projects on how best to organize and/or re-organize the flows of pharmaceutical products from the suppliers to its care units. Among these projects was the reconfiguration and arrangement of the establishment's pharmacy. In this article, an analysis of the pharmaceutical products consumption in the hospital, which identify the scale and the activities required across supply chain, is presented, which is followed by an explanation of the process modelling in order to identify the best practices. Finally, the different reengineering solutions as well as the method of classification and evaluation of these solutions are developed