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Article Dans Une Revue Analytical and Bioanalytical Chemistry Année : 2009

Lipid imaging with cluster time-of-flight secondary ion mass spectrometry.

Résumé

This brief article provides an overview of the current state of the art in biological imaging mass spectrometry using cluster time-of-flight secondary ion mass spectrometry (TOF-SIMS). Recent and spectacular improvements in terms of sensitivity of TOF-SIMS imaging methods have allowed many biological applications to recently be successfully tested, such as mapping of lipid disorders in human muscles of a patient suffering from dystrophy, localization of surfactins after the swarming of bacteria on a surface, or lipid mapping over whole-body animal sections.

Dates et versions

hal-00353508 , version 1 (15-01-2009)

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Alain Brunelle, Olivier Laprévote. Lipid imaging with cluster time-of-flight secondary ion mass spectrometry.. Analytical and Bioanalytical Chemistry, 2009, 393 (1), pp.31-5. ⟨10.1007/s00216-008-2367-3⟩. ⟨hal-00353508⟩
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