An integrated optimisation methodology is proposed to optimise the manufacturing cost as well as the structural performance and the weight of composite laminated plates manufactured by the resin transfer moulding (RTM) process. In the present approach, the fibre type, the number of fabrics, the layer stacking sequence and the fibre volume fraction are optimised to minimise the structural weight and the material cost of composite structure under the stiffness constraint and the mould filling time constraint which is a part of process cycle time. With the results obtained, it is investigated how the weight and the material cost are traded-off. The optimisation methodology suggests a guide to cost-effective material selection in the preliminary conceptual design stage.