Palladium-catalyzed intramolecular C-arylation of benzylic carbon: synthesis of 3-benzoxazolylisoindolinones by a sequence of Ugi-4CR/postfunctionalization. - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Journal of Organic Chemistry Année : 2008

Palladium-catalyzed intramolecular C-arylation of benzylic carbon: synthesis of 3-benzoxazolylisoindolinones by a sequence of Ugi-4CR/postfunctionalization.

Résumé

Submitting Ugi-adduct 4 to two consecutive metal-catalyzed intramolecular reactions, namely copper-catalyzed O-arylation and palladium-catalyzed C-arylation of benzylic carbon developed in the course of this study, affords the benzoxazolylisoindolinones in good to excellent yields.

Dates et versions

hal-00287338 , version 1 (11-06-2008)

Identifiants

Citer

Angela Salcedo, Luc Neuville, Jieping Zhu. Palladium-catalyzed intramolecular C-arylation of benzylic carbon: synthesis of 3-benzoxazolylisoindolinones by a sequence of Ugi-4CR/postfunctionalization.. Journal of Organic Chemistry, 2008, 73 (9), pp.3600-3. ⟨10.1021/jo800266y⟩. ⟨hal-00287338⟩
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