High-speed wave-mixing laser Doppler imaging, in vivo.
Résumé
An interferometric method for parallel optical spectroscopy in the kilohertz range is reported, as well as its experimental validation in the context of high speed laser Doppler imaging in vivo. The interferometric approach enables imaging in the low light conditions of a 2 kHz frame rate recording with a complementary metal-oxide semi-conductor (CMOS) camera. Observation of a mice cranium with near infrared ($\lambda$ = 785 nm) laser light in reflection configuration is reported. Doppler spectral images allegedly sensitive to blood flow are measured at several optical frequency detunings sequentially, to shift the spectral range of analysis in the radiofrequency (RF) spectrum.
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