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Article Dans Une Revue Tetrahedron Année : 2007

Synthesis and inclusion ability of a bis-beta-cyclodextrin pseudo-cryptand towards Busulfan anticancer agent

S. Menuel
Jp. Joly
  • Fonction : Auteur
J. Elysee
  • Fonction : Auteur
A. Marsura
  • Fonction : Auteur

Résumé

The synthesis of a C2-symmetric receptor including two β-cyclodextrins connected by urea linkers to a chiral diaza-crown ether organising platform is reported. This molecular system, long thought to be a potent selective carrier for chiral/achiral organic/inorganic guests at the supramolecular level, was found to be an efficient complexing tool towards the Busulfan anticancer agent.

Dates et versions

hal-00176637 , version 1 (04-10-2007)

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Citer

S. Menuel, Jp. Joly, Blandine Courcot, J. Elysee, N.-E. Ghernai, et al.. Synthesis and inclusion ability of a bis-beta-cyclodextrin pseudo-cryptand towards Busulfan anticancer agent. Tetrahedron, 2007, 63 (7), pp.1706-1714. ⟨10.1016/j.tet.2006.10.070⟩. ⟨hal-00176637⟩
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