Synthesis and inclusion ability of a bis-beta-cyclodextrin pseudo-cryptand towards Busulfan anticancer agent
Résumé
The synthesis of a C2-symmetric receptor including two β-cyclodextrins connected by urea linkers to a chiral diaza-crown ether organising platform is reported. This molecular system, long thought to be a potent selective carrier for chiral/achiral organic/inorganic guests at the supramolecular level, was found to be an efficient complexing tool towards the Busulfan anticancer agent.