Synthesis of aminopyrimidylindoles structurally related to meridianins - Archive ouverte HAL
Article Dans Une Revue Tetrahedron Année : 2007

Synthesis of aminopyrimidylindoles structurally related to meridianins

Résumé

The synthesis of new meridianin derivatives substituted at the C-5′ position of the 2-aminopyrimidine ring by various aryl groups and substituted or not by a methyl group on the indole nitrogen is described. The 2-aminopyrimidine ring was obtained via a Bredereck synthesis. Aryl groups were introduced by Suzuki cross-coupling after bromination of the 2-aminopyrimidine ring at the C-5′ position

Domaines

Chimie organique
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Dates et versions

hal-00170736 , version 1 (10-09-2007)

Identifiants

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Emilie Rossignol, Ali Youssef, Pascale Moreau, Michelle Prudhomme, Fabrice Anizon. Synthesis of aminopyrimidylindoles structurally related to meridianins. Tetrahedron, 2007, 63, pp.10169-10176. ⟨10.1016/j.tet.2007.07.095⟩. ⟨hal-00170736⟩
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