Synthesis of a staurosporine analogue possessing a 7-azaindole unit instead of an indole moiety - Archive ouverte HAL
Article Dans Une Revue Tetrahedron Letters Année : 2004

Synthesis of a staurosporine analogue possessing a 7-azaindole unit instead of an indole moiety

Résumé

The synthesis of a new staurosporine analogue possessing a 7-azaindole unit instead of an indole moiety is described. This synthesis could be achieved by coupling a sugar moiety previously tosylated in 2′ position to the azaindolocarbazole aglycone. Nucleophilic substitution on the carbon bearing the tosyl group yielded to the key cyclization leading to a compound in which the carbohydrate part is linked to both indole and azaindole nitrogens

Domaines

Chimie organique
Fichier principal
Vignette du fichier
TL2004-3.pdf (425.43 Ko) Télécharger le fichier
Origine Fichiers produits par l'(les) auteur(s)

Dates et versions

hal-00136311 , version 1 (13-03-2007)

Identifiants

Citer

Samir Messaoudi, Fabrice Anizon, Bruno Pfeiffer, Roy Golsteyn, Michelle Prudhomme. Synthesis of a staurosporine analogue possessing a 7-azaindole unit instead of an indole moiety. Tetrahedron Letters, 2004, 45, pp.4643-4647. ⟨10.1016/j.tetlet.2004.04.102⟩. ⟨hal-00136311⟩
130 Consultations
206 Téléchargements

Altmetric

Partager

More