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Article Dans Une Revue Journal of Molecular Neuroscience Année : 2006

Structural comparison of three crystalline complexes of a peptidic toxin with a synaptic acetylcholine recognition protein.

Yves Bourne
Scott B Hansen
  • Fonction : Auteur
Gerlind Sulzenbacher
Todd T Talley
  • Fonction : Auteur
Tom Huxford
  • Fonction : Auteur
Palmer Taylor
  • Fonction : Auteur
Pascale Marchot

Résumé

Many peptidic toxins from animal venoms target neuronal or peripheral synaptic receptors with high affinities and specificities. Hence, these toxins are not only potent natural weapons but also precise molecular tools for pharmacological studies of their receptors. Although they belong to various structural and/or functional subfamilies, they often share similar molecular features, such as a highly reticulated scaffold presenting specific binding determinants.
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Dates et versions

hal-00134316 , version 1 (01-03-2007)

Identifiants

  • HAL Id : hal-00134316 , version 1
  • PUBMED : 17192648

Citer

Yves Bourne, Scott B Hansen, Gerlind Sulzenbacher, Todd T Talley, Tom Huxford, et al.. Structural comparison of three crystalline complexes of a peptidic toxin with a synaptic acetylcholine recognition protein.. Journal of Molecular Neuroscience, 2006, 30 (1-2), pp.103-4. ⟨hal-00134316⟩

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