Article Dans Une Revue Phytochemistry Année : 2004

Antimicrobial and cytotoxic agents from Calophyllum inophyllum.

Résumé

The study of the chemical constituents of the root bark and the nut of Calophyllum inophyllum has resulted in the isolation and characterization of a xanthone derivative, named inoxanthone, 3, together with 12 known compounds: caloxanthones A, 4 and B, 5, macluraxanthone, 6, 1,5-dihydroxyxanthone, 7, calophynic acid, 8, brasiliensic acid, 9 inophylloidic acid, 10, friedelan-3-one, 11, calaustralin, 12, calophyllolide, 13, inophyllums C, 14 and E, 15. Their structures were established on the basis of spectral evidence. Their in vitro cytotoxicity against the KB cell line and their antibacterial activity and potency against a wide range of micro organisms were evaluated.

Dates et versions

hal-00016018 , version 1 (16-12-2005)

Identifiants

Citer

M.C. Yimdjo, A.G. Azebaze, A.E. Nkengfack, A.M. Meyer, B. Bodo, et al.. Antimicrobial and cytotoxic agents from Calophyllum inophyllum.. Phytochemistry, 2004, 65 (20), pp.2789-95. ⟨10.1016/j.phytochem.2004.08.024⟩. ⟨hal-00016018⟩

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