Thyroid and Corticosteroid Signaling in Amphibian Metamorphosis - Physiologie moléculaire et adaptation Accéder directement au contenu
Article Dans Une Revue Cells Année : 2022

Thyroid and Corticosteroid Signaling in Amphibian Metamorphosis

Bidisha Paul
Zachary R Sterner
  • Fonction : Auteur
Daniel R Buchholz
Laurent M Sachs
  • Fonction : Auteur
  • PersonId : 1060469

Résumé

In multicellular organisms, development is based in part on the integration of communication systems. Two neuroendocrine axes, the hypothalamic–pituitary–thyroid and the hypothalamic–pituitary–adrenal/interrenal axes, are central players in orchestrating body morphogenesis. In all vertebrates, the hypothalamic–pituitary–thyroid axis controls thyroid hormone production and release, whereas the hypothalamic–pituitary–adrenal/interrenal axis regulates the production and release of corticosteroids. One of the most salient effects of thyroid hormones and corticosteroids in post-embryonic developmental processes is their critical role in metamorphosis in anuran amphibians. Metamorphosis involves modifications to the morphological and biochemical characteristics of all larval tissues to enable the transition from one life stage to the next life stage that coincides with an ecological niche switch. This transition in amphibians is an example of a widespread phenomenon among vertebrates, where thyroid hormones and corticosteroids coordinate a post-embryonic developmental transition. The review addresses the functions and interactions of thyroid hormone and corticosteroid signaling in amphibian development (metamorphosis) as well as the developmental roles of these two pathways in vertebrate evolution.
Fichier principal
Vignette du fichier
2022-cells.pdf (1.72 Mo) Télécharger le fichier
Origine : Fichiers éditeurs autorisés sur une archive ouverte

Dates et versions

hal-03845656 , version 1 (23-11-2022)

Identifiants

Citer

Bidisha Paul, Zachary R Sterner, Daniel R Buchholz, Yun-Bo Shi, Laurent M Sachs. Thyroid and Corticosteroid Signaling in Amphibian Metamorphosis. Cells, 2022, 11 (10), pp.1595. ⟨10.3390/cells11101595⟩. ⟨hal-03845656⟩

Collections

MNHN CNRS PHYMA
5 Consultations
40 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More