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Journal Articles Helvetica Chimica Acta Year : 2024

Manganese‐Mediated Synthesis of NHC‐Phosphine Ligand Precursors


Alkylation of N ‐substituted imidazoles ImR’ (R’=2,4,6‐trimethylphenyl, 2,6‐diisopropylphenyl, 1‐adamantyl) with Mn(I) methylenephosphonium complexes [Cp(CO) 2 Mn(η 2 ‐ P,C ‐R 2 P=C(H)Ph)](BF 4 ) (PR 2 =PPh 2 , PCy 2 , trans ‐P=C(H)PhCH 2 CH 2 C=(H)Ph) followed by photochemical demetallation afforded a series of bidentate NHC‐phosphine ligand precursors [R 2 PC(H)PhImR’](BF 4 ) in moderate to good yield. The same strategy was successfully applied to N ‐functionalized imidazoles ImL (L=2‐pyridyl, CH 2 SMe, CH 2 ImMe) to afford selectively NHC core pincer pre‐ligands featuring phosphine/thioether, phosphine/NHC and phosphine/pyridine side arms. For PCy 2 derivatives, free NHCs in both bidentate and pincer series generated by deprotonation of the corresponding cationic precursors were shown to be persistent at room temperature.
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Saturday, September 21, 2024
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hal-04522796 , version 1 (27-03-2024)



Jérémy Willot, Sana Fatima, Carine Duhayon, Noël Lugan, Yves Canac, et al.. Manganese‐Mediated Synthesis of NHC‐Phosphine Ligand Precursors. Helvetica Chimica Acta, inPress, pp.e202400009. ⟨10.1002/hlca.202400009⟩. ⟨hal-04522796⟩
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