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Article Dans Une Revue Environment International Année : 2024

Characterization of organic contaminants in hair for biomonitoring purposes

Résumé

Biological monitoring is one way to assess human exposure to contaminants. Blood and urine are often used as biological matrices, but hair is an innovative and effective tool for quantifying more biomarkers over a wider exposure window. In order to improve the use of hair in exposure assessment, this article identifies relevant compounds in the literature to investigate hair contamination. Statistical analysis was performed to correlate the physical-chemical properties of the relevant compounds and their concentration levels in hair. Phthalates, pyrethroids and organophosphate flame retardants were chosen for further study of the interpretation of hair measurements for exposure assessment. No significant correlation was found between the average concentration levels in the literature and the physical-chemical properties of the selected compounds. This work also explores the properties of hair and the analytical process that may impact the quantification of organic contaminants in hair. The sample preparation method (sampling, storage, washing) were also studied and adaptations were suggested to improve the existing methods.
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hal-04387484 , version 1 (24-05-2024)

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Ashna Lallmahomed, Fabien Mercier, Nathalie Costet, Clémence Fillol, Nathalie Bonvallot, et al.. Characterization of organic contaminants in hair for biomonitoring purposes. Environment International, 2024, Environment International, 183, pp.108419. ⟨10.1016/j.envint.2024.108419⟩. ⟨hal-04387484⟩
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