With the explosion of e-commerce, optimizing parcel transportation has become increasingly important. We study the long-haul stage of parcel transportation which takes place between sorting centers and delivery depots and is performed on a twolevel hierarchical network. In our case study, we describe the application framework of this industrial problem faced by a French postal company: There are two vehicle types which must be balanced over the network on a daily basis, and there are two possible sorting points for each parcel, which allows a better consolidation of parcels. These industrial constraints are formalized in the Long-Haul Parcel Transportation Problem (LHPTP). We present a Mixed Integer Linear Program (MILP) and a hierarchical algorithm with aggregation of demands which uses the MILP as a subroutine. We perform numerical experiments on large-size datasets provided by a postal company, which consist of approximately 2500 demands on a network of 225 sites. These tests enable the tuning of certain parameters resulting in a tailored heuristic for the LHPTP. Our algorithm can serve as a decision aid tool for transportation managers to build daily transportation plans, modeled on solutions produced given daily demand forecasts, and can also be used to improve the network design.