Report of One-Year Prospective Surveillance of SARS-CoV-2 in Dogs and Cats in France with Various Exposure Risks: Confirmation of a Low Prevalence of Shedding, Detection and Complete Sequencing of an Alpha Variant in a Cat - Centre International de Recherche en Infectiologie Accéder directement au contenu
Article Dans Une Revue Viruses Année : 2021

Report of One-Year Prospective Surveillance of SARS-CoV-2 in Dogs and Cats in France with Various Exposure Risks: Confirmation of a Low Prevalence of Shedding, Detection and Complete Sequencing of an Alpha Variant in a Cat

Solène Denolly
Bertrand Boson
Sophie Angelloz-Pessey
  • Fonction : Auteur
Sophie Levaltier
  • Fonction : Auteur
Nicolas Nesi
  • Fonction : Auteur
Sandrine Corbet
  • Fonction : Auteur
Bryce Leterrier
  • Fonction : Auteur
Matthieu Fritz
François-Loïc Cosset

Résumé

Despite the probable zoonotic origin of SARS-CoV-2, only limited research efforts have been made to understand the role of companion animals in SARS-CoV-2 epidemiology. According to recent serological prevalence studies, human-to-companion animal transmission is quite frequent, which led us to consider that the risk of SARS-CoV-2 transmission from animal to human, albeit negligible in the present context, may have been underestimated. In this study, we provide the results of a prospective survey that was conducted to evaluate the SARS-CoV-2 isolation rate by qRT-PCR in dogs and cats with different exposure risks and clinical statuses. From April 2020 to April 2021, we analyzed 367 samples and investigated the presence of SARS-CoV-2 RNA using qRT-PCR. Only four animals tested positive, all of them being cats. Three cats were asymptomatic and one presented a coryza-like syndrome. We describe in detail the infection in two cats and the associated clinical characteristics. Importantly, we obtained SARS-CoV-2 genomes from one infected animal and characterized them as Alpha variants. This represents the first identification of the SARS-CoV-2 Alpha variant in an infected animal in France.
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hal-04584811 , version 1 (24-05-2024)

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Emilie Krafft, Solène Denolly, Bertrand Boson, Sophie Angelloz-Pessey, Sophie Levaltier, et al.. Report of One-Year Prospective Surveillance of SARS-CoV-2 in Dogs and Cats in France with Various Exposure Risks: Confirmation of a Low Prevalence of Shedding, Detection and Complete Sequencing of an Alpha Variant in a Cat. Viruses, 2021, 13 (9), pp.1759. ⟨10.3390/v13091759⟩. ⟨hal-04584811⟩
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