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authIdHal_s : francois-trottein

Activation of invariant NKT cells by the helminth parasite schistosoma mansoni

Thierry Mallevaey , Jean Pierre Zanetta , Christelle Faveeuw , Josette Fontaine , Emmanuel Maes , et al.
Journal of Immunology, 2006, 176, pp.2476-85. ⟨10.4049/jimmunol.176.4.2476⟩
Journal articles hal-00085717v1
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Mechanisms of Bacterial Superinfection Post-influenza: A Role for Unconventional T Cells

Christophe Paget , François Trottein
Frontiers in Immunology, 2019, 10, pp.336. ⟨10.3389/fimmu.2019.00336⟩
Journal articles hal-02398297v1
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Production of Interleukin-20 cytokines limits bacterial clearance and lung inflammation during infection by Streptococcus pneumoniae

Fahima Madouri , Olivia Barada , Gwenola Kervoaze , François Trottein , Muriel Pichavant , et al.
EBioMedicine, 2018, 37, pp.417-427. ⟨10.1016/j.ebiom.2018.10.031⟩
Journal articles hal-02398317v1
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CD3(bright) signals on γδ T cells identify IL-17A-producing Vγ6Vδ1(+) T cells.

Christophe Paget , M T Chow , N A Gherardin , P A Beavis , a P Uldrich , et al.
Immunology and Cell Biology, 2015, 93 (2), pp.198-212. ⟨10.1038/icb.2014.94⟩
Journal articles inserm-01116326v1

Toll-like receptor (TLR)2 and TLR3 synergy and cross-inhibition in murine myeloid dendritic cells.

François Vanhoutte , Christophe Paget , Laetitia Breuilh , Josette Fontaine , Catherine Vendeville , et al.
Immunology Letters, 2008, 116 (1), pp.86-94. ⟨10.1016/j.imlet.2007.11.014⟩
Journal articles istex hal-00318560v1

Toll-like receptor (TLR)2 and TLR3 sensing is required for dendritic cell activation, but dispensable to control Schistosoma mansoni infection and pathology.

François Vanhoutte , Laetitia Breuilh , Josette Fontaine , Claudia S Zouain , Thierry Mallevaey , et al.
Microbes and Infection, 2007, 9 (14-15), pp.1606-13. ⟨10.1016/j.micinf.2007.09.013⟩
Journal articles istex hal-00318524v1
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CPCN - BILAN DE MANDATURE 2016 – 2021

Olivier Coutard , Pierre-Olivier Amblard , Claude Amra , Brigitte Bacroix , Pascal Barone , et al.
2021
Preprints, Working Papers, ... hal-03413289v1
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Potential causes and consequences of gastrointestinal disorders during a SARS-CoV-2 infection

François Trottein , Harry Sokol
Cell Reports, 2020, 32 (3), pp.107915. ⟨10.1016/j.celrep.2020.107915⟩
Journal articles hal-02934850v1

COVID-19 and flu: conserved or specific immune signature?

Christophe Paget , François Trottein
Cellular and molecular immunology, 2021, 18 (2), pp.245-246. ⟨10.1038/s41423-020-00595-3⟩
Journal articles hal-03534675v1
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The lung–gut axis during viral respiratory infections: the impact of gut dysbiosis on secondary disease outcomes

Valentin Sencio , Marina Gomes Machado , François Trottein
Mucosal Immunology, 2021, 14 (2), pp.296-304. ⟨10.1038/s41385-020-00361-8⟩
Journal articles inserm-03385636v1
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Short-Chain Fatty Acids as a Potential Treatment for Infections: a Closer Look at the Lungs

Marina Gomes Machado , Valentin Sencio , François Trottein
Infection and Immunity, 2021, 89 (9), pp.e0018821. ⟨10.1128/IAI.00188-21⟩
Journal articles inserm-03385656v1

Schistosoma mansoni activates host microvascular endothelial cells to acquire an anti-inflammatory phenotype

François Trottein , Laurence Descamps , Sophie Nutten , Marie-Pierre Dehouck , Véronique Angeli , et al.
Infection and Immunity, 1999, 67 (7), pp.3403-3409
Journal articles hal-00531758v1
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Exogenous Activation of Invariant Natural Killer T Cells by α-Galactosylceramide Reduces Pneumococcal Outgrowth and Dissemination Postinfluenza

Adeline Barthélémy , Stoyan Ivanov , Maya Hassane , Josette Fontaine , Béatrice Heurtault , et al.
mBio, 2016, 7 (6), ⟨10.1128/mBio.01440-16⟩
Journal articles hal-02185406v1
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TLR9-mediated dendritic cell activation uncovers mammalian ganglioside species with specific ceramide backbones that activate invariant natural killer T cells

Christophe Paget , Shenglou Deng , Daphnée Soulard , David A Priestman , Silvia Speca , et al.
PLoS Biology, 2019, 17 (3), pp.e3000169. ⟨10.1371/journal.pbio.3000169⟩
Journal articles inserm-02143816v1

Type I IFN Receptor Signaling Controls IL7-Dependent Accumulation and Activity of Protumoral IL17A-Producing γδT Cells in Breast Cancer

Emmanuel Patin , Daphnée Soulard , Sébastien Fleury , Maya Hassane , David Dombrowicz , et al.
Cancer Research, 2018, 78 (1), pp.195-204. ⟨10.1158/0008-5472.CAN-17-1416⟩
Journal articles inserm-02436039v1
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Gut microbiota-derived short-chain fatty acids regulate IL-17 production by mouse and human intestinal γδ T cells

Louise Dupraz , Aurélie Magniez , Nathalie Rolhion , Mathias L Richard , Grégory da Costa , et al.
Cell Reports, 2021, 36 (1), pp.109332. ⟨10.1016/j.celrep.2021.109332⟩
Journal articles hal-03282473v1

The hypothalamus as a hub for SARS-CoV-2 brain infection and pathogenesis

Sreekala Nampoothiri , Florent Sauve , Gaëtan Ternier , Daniela Fernandois , Caio Coelho , et al.
2021
Preprints, Working Papers, ... hal-03454404v1
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A druggable copper-signalling pathway that drives inflammation

Stéphanie Solier , Sebastian Müller , Tatiana Cañeque , Antoine Versini , Arnaud Mansart , et al.
Nature, 2023, 617 (7960), pp.386-394. ⟨10.1038/s41586-023-06017-4⟩
Journal articles inserm-04170826v1
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Large scale screening discovers clofoctol as an inhibitor of SARS-CoV-2 replication that reduces COVID-19-like pathology

Sandrine Belouzard , Arnaud Machelart , Valentin Sencio , Thibaut Vausselin , Eik Hoffmann , et al.
2021
Preprints, Working Papers, ... hal-03357964v1
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Scavenger Receptors in Human Airway Epithelial Cells: Role in Response to Double-Stranded RNA

Audrey Dieudonné , David Torres , Simon J. Blanchard , Solenne Taront , Pascale Jeannin , et al.
PLoS ONE, 2012, 7 (8), pp.e41952. ⟨10.1371/journal.pone.0041952⟩
Journal articles inserm-03377755v1

Pseudomonas aeruginosa proteolytically alters the interleukin 22-dependent lung mucosal defense

Antoine Guillon , Deborah Brea , Eric Morello , Aihua Tang , Youenn Jouan , et al.
Virulence, 2016, 8 (6), pp.810-820. ⟨10.1080/21505594.2016.1253658⟩
Journal articles hal-03601744v1
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Alteration of the gut microbiota following SARS-CoV-2 infection correlates with disease severity in hamsters

Valentin Sencio , Arnaud Machelart , Cyril Robil , Nicolas Benech , Eik Hoffmann , et al.
Gut microbes, 2021, 14 (1), ⟨10.1080/19490976.2021.2018900⟩
Journal articles hal-03518769v1
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Alteration of Flt3-Ligand-dependent de novo generation of conventional dendritic cells during influenza infection contributes to respiratory bacterial superinfection

Ranin Beshara , Valentin Sencio , Daphnée Soulard , Adeline Barthélémy , Josette Fontaine , et al.
PLoS Pathogens, 2018, 14 (10), pp.e1007360. ⟨10.1371/journal.ppat.1007360⟩
Journal articles inserm-02078841v1

CPCN - BILAN DE MANDATURE 2016 – 2021

Olivier Coutard , Pierre-Olivier Amblard , Claude Amra , Brigitte Bacroix , Pascal Barone , et al.
Conférence des Présidents du Comité National, CNRS, 2021, Paris, France
Conference papers hal-03406826v1

Activation of invariant Natural Killer T lymphocytes in response to the α-galactosylceramide analogue KRN7000 encapsulated in PLGA-based nanoparticles and microparticles.

Elodie Macho Fernandez , Jiang Chang , Josette Fontaine , Emilie Bialecki , Fabien Rodriguez , et al.
International Journal of Pharmaceutics, 2012, 423 (1), pp.45-54. ⟨10.1016/j.ijpharm.2011.04.068⟩
Journal articles istex hal-00604980v1
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Influenza infection rewires energy metabolism and induces browning features in adipose cells and tissues

Asma Ayari , Manuel Rosa-Calatrava , Steve S. Lancel , Johanna Barthelemy , Andrés Pizzorno , et al.
Communications Biology, 2020, 3 (1), ⟨10.1038/s42003-020-0965-6⟩
Journal articles hal-02959942v2

Spleen-Resident CD4+ and CD4− CD8α− Dendritic Cell Subsets Differ in Their Ability to Prime Invariant Natural Killer T Lymphocytes

Emilie Bialecki , Elodie Macho Fernandez , Stoyan Ivanov , Christophe Paget , Josette Fontaine , et al.
PLoS ONE, 2011, 6 (10), pp.e26919. ⟨10.1371/journal.pone.0026919⟩
Journal articles hal-02361403v1

Semisynthetic glycoconjugate based on dual role protein/PsaA as a pneumococcal vaccine

Maruthi Prasanna , Daphnée Soulard , Emilie Camberlein , Nicolas Ruffier , Annie Lambert , et al.
European Journal of Pharmaceutical Sciences, 2019, 129, pp.31-41. ⟨10.1016/j.ejps.2018.12.013⟩
Journal articles hal-02197013v1

Activation of invariant NKT cells by toll-like receptor 9-stimulated dendritic cells requires type I interferon and charged glycosphingolipids.

Christophe Paget , Thierry Mallevaey , Anneliese O Speak , David Torres , Josette Fontaine , et al.
Immunity, 2007, 27 (4), pp.597-609. ⟨10.1016/j.immuni.2007.08.017⟩
Journal articles hal-00317178v1
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Alteration of the gut microbiota’s composition and metabolic output correlates with COVID-19-like severity in obese NASH hamsters

Valentin Sencio , Nicolas Benech , Cyril Robil , Lucie Deruyter , Séverine Heumel , et al.
Gut microbes, 2022, 14 (1), ⟨10.1080/19490976.2022.2100200⟩
Journal articles inserm-03741928v1