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Editorial.
Françoise Ochsenbein
,
Xavier Morelli
,
Chandra Verma
Progress in Biophysics and Molecular Biology, 2015, 119 (1), pp.1
Journal articles
hal-01201641v1
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Genetic, structural, and chemical insights into the dual function of GRASP55 in germ cell Golgi remodeling and JAM-C polarized localization during spermatogenesis
Amandine Cartier-Michaud
,
Anne-Laure Bailly
,
Stéphane Betzi
,
Xiaoli Shi
,
Jean-Claude Lissitzky
,
et al.
Journal articles
hal-01542697v1
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Discovery of Small-Molecule Inhibitors of the PTK7/β-Catenin Interaction Targeting the Wnt Signaling Pathway in Colorectal Cancer
Laetitia Ganier
,
Stéphane Betzi
,
Carine Derviaux
,
Philippe Roche
,
Charlotte Dessaux
,
et al.
Journal articles
hal-03817750v1
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In silico molecular target prediction unveils mebendazole as a potent MAPK14 inhibitor
Jeremy Ariey‐bonnet
,
Kendall Carrasco
,
Marion Le Grand
,
Laurent Hoffer
,
Stéphane Betzi
,
et al.
Journal articles
hal-02989358v1
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Optimization of a fragment linking hit toward Dengue and Zika virus NS5 methyltransferases inhibitors
Jessica Hernandez
,
Laurent Hoffer
,
Bruno Coutard
,
Gilles Quérat
,
Philippe Roche
,
et al.
Journal articles
inserm-02378768v1
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2P2Idb v2: update of a structural database dedicated to orthosteric modulation of protein–protein interactions
Marie-Jeanne Basse
,
Stéphane Betzi
,
Xavier Morelli
,
Philippe Roche
Journal articles
hal-01307114v1
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Rôle en cancérologie et ciblage du récepteur à activité tyrosine kinase PTK7
Laetitia Ganier
,
Xavier Morelli
,
Jean-Paul Borg
Journal articles
hal-03152194v1
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Fr-PPIChem: An Academic Compound Library Dedicated to Protein-Protein Interactions
Nicolas Bosc
,
Christophe Muller
,
Laurent Hoffer
,
David Lagorce
,
Stéphane Bourg
,
et al.
Journal articles
hal-02569625v1
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Integrated Strategy for Lead Optimization Based on Fragment Growing: The Diversity-Oriented-Target-Focused-Synthesis Approach
Laurent Hoffer
,
Yuliia Voitovich
,
Brigitt Raux
,
Kendall Carrasco
,
Christophe Muller
,
et al.
Journal articles
hal-02067797v1
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Identification of a Src kinase SH3 binding site in the C-terminal domain of the human ErbB2 receptor tyrosine kinase.
Olivier Bornet
,
Matthieu Nouailler
,
Michaël Feracci
,
Corinne Sebban-Kreuzer
,
Deborah Byrne
,
et al.
Journal articles
hal-01458194v1
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The NANOTUMOR consortium - Towards the Tumor Cell Atlas
Florent Colin
,
Kristine Schauer
,
Ali Hamiche
,
Pierre Martineau
,
Jean-Paul Borg
,
et al.
Journal articles
hal-03169719v1
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Mutational analysis of the DOK2 haploinsufficient tumor suppressor gene in chronic myelomonocytic leukemia (CMML).
Emilie Coppin
,
Véronique Gelsi-Boyer
,
Xavier Morelli
,
Nathalie Cervera
,
Anne Murati
,
et al.
Journal articles
inserm-01069773v1
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Interaction between the C-terminal domains of N and P proteins of measles virus investigated by NMR.
Cedric Bernard
,
Stéphane Gely
,
Jean-Marie Bourhis
,
Xavier Morelli
,
Sonia Longhi
,
et al.
Journal articles
hal-00473784v1
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Dual protein kinase and nucleoside kinase modulators for rationally designed polypharmacology
Kahina Hammam
,
Magali Saez-Ayala
,
Etienne Rebuffet
,
Laurent Gros
,
Sophie Lopez
,
et al.
Journal articles
hal-01643359v1
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Alteration of a Single Tryptophan Residue of the Cellulose-binding Domain Blocks Secretion of the Erwinia chrysanthemi Cel5 Cellulase (ex-EGZ) via the Type II System
Virginie Chapon
,
Helen D Simpson
,
Xavier Morelli
,
Emmanuel Brun
,
Frederic Barras
Journal articles
istex
hal-01560905v1
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Crystal structure of the vaccinia virus DNA polymerase holoenzyme subunit D4 in complex with the A20 N-terminal domain
Céline Contesto-Richefeu
,
Nicolas Tarbouriech
,
Xavier Brazzolotto
,
Stéphane Betzi
,
Xavier Morelli
,
et al.
Journal articles
hal-01132360v1
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CRCM5484: A BET- BDII Selective Compound With Differential Anti-Leukemic Drug Modulation
Kendall Carrasco
,
Camille Montersino
,
Carine Derviaux
,
Magali Saez-Ayala
,
Laurent Hoffer
,
et al.
Journal articles
hal-03624836v1
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Protein protein interaction inhibition (2P2I) combining high throughput and virtual screening: Application to the HIV-1 Nef protein.
Stéphane Betzi
,
Audrey Restouin
,
Sandrine Opi
,
Stefan T Arold
,
Isabelle Parrot
,
et al.
Proceedings of the National Academy of Sciences of the United States of America, 2007, 104 (49), pp.19256-61. ⟨10.1073/pnas.0707130104⟩
Journal articles
hal-00473817v1
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Structural recognition mechanisms between human Src homology domain 3 (SH3) and ALG-2-interacting protein X (Alix)
Xiaoli Shi
,
Stéphane Betzi
,
Adrien Lugari
,
Sandrine Opi
,
Audrey Restouin
,
et al.
Journal articles
hal-00717171v1
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A specific protein disorder catalyzer of HIV-1 Nef
Adrien Lugari
,
Sebastian Breuer
,
Thibault Coursindel
,
Sandrine Opi
,
Audrey Restouin
,
et al.
Journal articles
istex
hal-00662295v1
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Structural and Genetic Analyses Reveal a Key Role in Prophage Excision for the TorI Response Regulator Inhibitor
Latifa Elantak
,
Mireille Ansaldi
,
Francoise Guerlesquin
,
Vincent Méjean
,
Xavier Morelli
Journal articles
hal-02018141v1
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CovaDOTS: In Silico Chemistry-Driven Tool to Design Covalent Inhibitors Using a Linking Strategy
Laurent Hoffer
,
Magali Saez-Ayala
,
Dragos Horvath
,
Alexandre Varnek
,
Xavier Morelli
,
et al.
Journal articles
hal-02145507v1
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Chemistry-driven Hit-to-lead Optimization Guided by Structure-based Approaches
Laurent Hoffer
,
Christophe Muller
,
Philippe Roche
,
Xavier Morelli
Journal articles
hal-02145522v1
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Identification and biophysical assessment of the molecular recognition mechanisms between the human haemopoietic cell kinase Src homology domain and ALG-2-interacting protein X
Xiaoli Shi
,
Sandrine Opi
,
Adrien Lugari
,
Audrey Restouin
,
Thibault Coursindel
,
et al.
Journal articles
hal-00600207v1
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Solution structure of HndAc: a thioredoxin-like domain involved in the NADP-reducing hydrogenase complex.
Matthieu Nouailler
,
Xavier Morelli
,
Olivier Bornet
,
Bernard Chetrit
,
Zorah Dermoun
,
et al.
Journal articles
hal-00475666v1
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Identification and biophysical assessment of the molecular recognition mechanisms between the human hemopoietic cell kinase Src homology domain 3 and ALG-2-interacting protein X
Xiaoli Shi
,
Sandrine Opi
,
Adrien Lugari
,
Audrey Restouin
,
Thibault Coursindel
,
et al.
Journal articles
hal-00517249v1
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Stereoselective synthesis of original spirolactams displaying promising folded structures.
Guilhem Chaubet
,
Thibault Coursindel
,
Xavier Morelli
,
Stéphane Betzi
,
Philippe Roche
,
et al.
Journal articles
hal-00871067v1
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CD47-SIRPα Controls ADCC Killing of Primary T Cells by PMN Through a Combination of Trogocytosis and NADPH Oxidase Activation
Françoise Gondois-Rey
,
Thomas Miller
,
Vladimir Laletin
,
Xavier Morelli
,
Yves Collette
,
et al.
Journal articles
hal-03857250v1
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Discovery of a PDZ Domain Inhibitor Targeting the Syndecan/Syntenin Protein–Protein Interaction: A Semi-Automated “Hit Identification-to-Optimization” Approach
Laurent Hoffer
,
Manon Garcia
,
Raphael Leblanc
,
Mikael Feracci
,
Stéphane Betzi
,
et al.
Journal articles
hal-04048842v1
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Aminoacylase 1-catalysed deacetylation of bioactives epoxides mycotoxin-derived mercapturates; 3,4-epoxyprecocenes as models of cytotoxic epoxides
Pierre Stocker
,
Jean Michel Brunel
,
Leandro De Rezende
,
Antonia Tavares-Do Amaral
,
Xavier Morelli
,
et al.
Journal articles
istex
hal-01460427v1
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