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Multicomponent organocatalytic synthesis of isoxazolidin-5-ones

Julien Annibaletto , Christophe Berini , Vincent Levacher , Sylvain Oudeyer , Jean-François Brière
European symposium on organic chemistry (ESOC, 21, 2019), Jul 2019, Vienne, Austria
Poster communications hal-02376286v1

Promising chemical delivery system into the central nervous system of [18F]FLT for PET imaging studies of low-grade brain tumours.

F. Gourand , A. Henry , M. Ibazizene , M. Dhilly , Cyril Papamicaël , et al.
Annual Congress of the European-Association-of-Nuclear-Medicine (EANM, 28, 2015), Oct 2015, Hambourg, Germany. pp.476-477
Conference papers hal-02024980v1

Combination between meldrum’s acid derivatives and chiral ammonium phenoxides for an assymetric decarboxylative protonation reaction

Fabien Legros , Jean-François Brière , Sylvain Oudeyer , Vincent Levacher
Journées de chimie organique (JCO, 2016), Sep 2016, Palaiseau, France
Poster communications hal-02374227v1

Phase-transfer catalyzed asymmetric decarboxylative protonation reaction involving Meldrum’s acid derivatives and phenols

Fabien Legros , Thomas Martzel , Sylvain Oudeyer , Jean-François Brière , Vincent Levacher
European symposium on organic chemistry (ESOC, 20, 2017), Jul 2017, Cologne, Germany
Poster communications hal-02373920v1

Palladium-Catalyzed Carbonylation of (Hetero)Aryl, Alkenyl and Allyl Halides by Means of N-Hydroxysuccinimidyl Formate as CO Surrogate

Anaïs Barré , Mihaela-Liliana Tîntas , Florent Alix , Vincent Gembus , Cyril Papamicaël , et al.
Journal of Organic Chemistry, 2015, 80 (13), pp.6537-6544. ⟨10.1021/acs.joc.5b01119⟩
Journal articles hal-02046139v1

Enantioselective Organocatalyzed alpha-Sulfanylation of Isoxazolidin-5-ones : an Approach to beta 2,2-Amino Acids

Timothée Cadard , Vincent Levacher , Perrio Stéphane
Journée de l’Ecole doctorale normande de chimie (JEDNC, 2016), Jun 2016, Caen, France
Conference papers hal-02299440v1

Access to Highly Enantioenriched Donepezil-like 1,4-Dihydropyridines as Promising Anti-Alzheimer Prodrug Candidates via Enantioselective Tsuji Allylation and Organocatalytic Aza-Ene-Type Domino Reactions

Mihaela-Liliana Tîntas , R. Azzouz , L. Peauger , Vincent Gembus , Emilie Petit , et al.
Journal of Organic Chemistry, 2018, 83 (17), pp.10231-10240. ⟨10.1021/acs.joc.8b01442⟩
Journal articles hal-02024535v1

Multicomponent organocatalytic synthesis of 1,5-diazabicyclo[3.3.0]octane-2,6-diones and derivatives: regio- and stereoselective approaches

Arthur Lebrêne , Etienne Pair , Christophe Berini , Romain Noël , Vincent Levacher , et al.
Journées de chimie organique (JCO, 2019), Oct 2019, Palaiseau, France
Poster communications hal-02376368v1
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Recent Advances in Catalytic and Technology-Driven Radical Addition to N,N-Disubstituted Iminium Species

Sylvain Oudeyer , Vincent Levacher , Hélène Beucher , Jean-François Brière
Molecules, 2023, 28 (3), pp.1071. ⟨10.3390/molecules28031071⟩
Journal articles hal-03954900v1

Synthesis of strained cyclic peptides via an aza-Michael-acyl-transfer reaction cascade.

Jochem P A Rutters , Yvette Verdonk , Remko de Vries , Steen Ingemann , Henk Hiemstra , et al.
Chemical Communications, 2012, 48 (65), pp.8084-8086. ⟨10.1039/c2cc34121b⟩
Journal articles hal-00997077v1

Enantioselective desymmetrization of prochiral ketones via an organocatalytic deprotonation process

Aurélie Claraz , Sylvain Oudeyer , Vincent Levacher
Tetrahedron: Asymmetry, 2013, 24 (12), pp.764-768. ⟨10.1016/j.tetasy.2013.05.011⟩
Journal articles hal-01015427v1
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Organocatalyzed one‐pot sequential deracemization of aromatic ketones bearing a tertiary stereogenic center

Claire Segovia , Jérémy Godemert , Jean-François Brière , Vincent Levacher , Sylvain Oudeyer
Advanced Synthesis and Catalysis, 2022, 364 (22), pp.3794-3799. ⟨10.1002/adsc.202200857⟩
Journal articles hal-03822325v1

Scaffold hopping strategy toward original pyrazolines as selective CB₂ receptor ligands.

Vincent Gembus , Christophe Furman , Régis Millet , Roxane Mansouri , Philippe Chavatte , et al.
European Journal of Medicinal Chemistry, 2012, 58, pp.396-404. ⟨10.1016/j.ejmech.2012.10.031⟩
Journal articles istex hal-00997079v1
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Organocatalytic Multicomponent Synthesis of α/β‐Dipeptide Derivatives

Thomas Martzel , Julien Annibaletto , Pierre Millet , Etienne Pair , Morgane Sanselme , et al.
Chemistry - A European Journal, 2020, 26, pp.8541. ⟨10.1002/chem.202001214⟩
Journal articles hal-02523950v1
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CO2 valorization using epoxides under mild conditions

Viviana Contreras Moreno , Lionel Estel , Laurent Bischoff , Vincent Levacher , Marie-Pierre Denieul , et al.
10th World Congress of Chemical Engineering (WCCE10), Oct 2017, Barcelona, Spain.
Poster communications hal-02409702v1

Enantioselective organocatalyzed α-sulfanylation of Iisoxazolidin-5-ones : an approach to β-2,2-amino acids

Timothée Cadart , Vincent Levacher , Perrio Stéphane , Jean-François Brière
SCC-11 ( 11th International Symposium on Carbanion Chemistry), Jul 2016, Rouen, France
Poster communications hal-01871581v1

Chiral ammonium aryloxides as nucleophilic organocatalysts : Application to the enantioselective decarboxylative protonation of Meldrum’s acid derivatives

Sylvain Oudeyer , Fabien Legros , Thomas Martzel , Julien Annibaletto , Jean-François Brière , et al.
Journées de chimie organique (JCO, 2019), Oct 2019, Palaiseau, France
Poster communications hal-02368726v1
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Chemical Delivery System of MIBG to the Central Nervous System: Synthesis, 11 C-Radiosynthesis, and in Vivo Evaluation

Fabienne Gourand , Delphine Patin , Axelle Henry , Meźiane Ibazizeǹe , Martine Dhilly , et al.
ACS Medicinal Chemistry Letters, 2019, 10 (3), pp.352-357. ⟨10.1021/acsmedchemlett.8b00642⟩
Journal articles hal-03020265v1

Dihydroquinoline derivatives as redox chemical delivery systems (CDS) or “bio-oxidisable” prodrugs for brain delivery of acetylcholinesterase inhibitors: design, synthesis, [11C]radiosynthesis and biological evaluation

P Bohn , F Gourand , C Papamicaël , M Ibazizène , M Dhilly , et al.
Journées Neurosciences, Workshop FLI, Nov 2015, Orsay, France
Poster communications hal-02386737v1

New developments in redox chemical delivery systems by means of 1,4-dihydroquinoline-based targetor: Application to galantamine delivery to the brain

Mihaela-Liliana Tîntas , Lénaïg Foucout , Sylvain Petit , Sylvain Oudeyer , Fabienne Gourand , et al.
European Journal of Medicinal Chemistry, 2014, 81, pp.218-226. ⟨10.1016/j.ejmech.2014.05.022⟩
Journal articles hal-01141464v1

Organocatalyzed enantioselective protonation of silyl enol ethers: scope, limitations, and application to the preparation of enantioenriched homoisoflavones.

Thomas Poisson , Vincent Gembus , Vincent Dalla , Sylvain Oudeyer , Vincent Levacher
Journal of Organic Chemistry, 2010, 75 (22), pp.7704-7716. ⟨10.1021/jo101585t⟩
Journal articles hal-00992146v1

Synthesis and Stability Evaluation of New HYNIC Derivatives as Ligands for Technetium-99m

Yoann Joyard , Laurent Bischoff , Vincent Levacher , Cyril Papamicaël , Pierre Vera , et al.
Letters in Organic Chemistry, 2014, 11 (3), pp.208-214. ⟨10.2174/15701786113106660087⟩
Journal articles hal-01141349v1

Deracemization of a-Substituted Carbonyl Compounds via Catalytic Enantioselective

Aurélie Claraz , Sylvain Oudeyer , Vincent Levacher
Current Organic Chemistry, 2012, 16 (19), pp.2192-2205. ⟨10.2174/138527212803520308⟩
Journal articles hal-01016900v1

Recent advances in organocatalysis by means of chiral cooperative ion-pairing

Vincent Levacher
Séminaire national, Le Mans Université, Jan 2016, Le Mans, France
Conference papers hal-02390807v1

Pd- and Cu-Catalyzed Stereo- and Regiocontrolled Decarboxylative / C-H Fluoroalkenylation of Heteroarenes

Cédric Schneider , Kevin Rousée , Samuel Couve-Bonnaire , Xavier Pannecoucke , Vincent Levacher , et al.
International Symposium on C-H Activation (ISCHA, 2, 2014), Jun 2014, Rennes, France
Poster communications hal-02385166v1

A Unique (3+2) Annulation Reaction between Meldrum's Acid and Nitrones: Mechanistic Insight by ESI-IMS-MS and DFT Studies

N. Lespes , E. Pair , C. Maganga , M. Bretier , Vincent Tognetti , et al.
Chemistry - A European Journal, 2018, 24 (16), pp.4086-4093. ⟨10.1002/chem.201705714⟩
Journal articles hal-02024514v1

Rational design of carbamate-based dual binding site and central AChE inhibitors by a “biooxidisable” prodrug approach: Synthesis, in vitro evaluation and docking studies

Mihaela-Liliana Tîntas , Vincent Gembus , F. Alix , A. Barré , Gaël Coadou , et al.
European Journal of Medicinal Chemistry, 2018, 155, pp.171-182. ⟨10.1016/j.ejmech.2018.05.057⟩
Journal articles hal-02024536v1

Chiral Ammonium Aryloxides as Brønsted Base Catalysts for the Henry Reaction of Nitroalkanes to Aromatic and Aliphatic Aldehydes

Jérémy Godemert , Sylvain Oudeyer , Vincent Levacher
ChemistrySelect, 2016, 1 (12), pp.3184-3188. ⟨10.1002/slct.201600776⟩
Journal articles hal-02046208v1

Catalytic Enantioselective Syntheses of Isoxazolidin-5-ones

J. Annibaletto , Sylvain Oudeyer , Vincent Levacher , Jean-François Brière
Synthesis: Journal of Synthetic Organic Chemistry, 2017, 49 (10), pp.2117-2128. ⟨10.1055/s-0036-1588765⟩
Journal articles hal-02046255v1

An Overview of the Synthesis of Highly Versatile N-Hydroxysuccinimide Esters

Anaïs Barré , Mihaela-Liliana Tîntas , Vincent Levacher , Cyril Papamicaël , Vincent Gembus
Synthesis: Journal of Synthetic Organic Chemistry, 2017, 49 (3), pp.472-483. ⟨10.1055/s-0036-1588607⟩
Journal articles hal-02046258v1