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Inhibiting Type VI Secretion System Activity with a Biomimetic Peptide Designed To Target the Baseplate Wedge Complex
Y. Cherrak
,
I. Filella-Merce
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V. Schmidt
,
D. Byrne
,
V. Sgoluppi
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et al.
Journal articles
pasteur-03429012v1
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Integrated Strategy for Lead Optimization Based on Fragment Growing: The Diversity-Oriented-Target-Focused-Synthesis Approach
Laurent Hoffer
,
Yuliia Voitovich
,
Brigitt Raux
,
Kendall Carrasco
,
Christophe Muller
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et al.
Journal articles
hal-02067797v1
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Exploring Selective Inhibition of the First Bromodomain of the Human Bromodomain and Extra-terminal Domain (BET) Proteins
Brigitt Raux
,
Yuliia Voitovich
,
Carine Derviaux
,
Adrien Lugari
,
Etienne Rebuffet
,
et al.
Journal articles
hal-01439086v1
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Structural and Biochemical Characterization of the Cop9 Signalosome CSN5/CSN6 Heterodimer
Melissa Birol
,
Radoslav Ivanov Enchev
,
André Padilla
,
Florian Stengel
,
Ruedi Aebersold
,
et al.
Journal articles
hal-02359383v1
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Protein-Protein Interaction Inhibition (2P21)-Oriented Chemical Library Accelerates Hit Discovery
Sabine Milhas
,
Brigitt Raux
,
Stéphane Betzi
,
Carine Derviaux
,
Philippe Roche
,
et al.
Journal articles
hal-01439116v1
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2P2Idb v2: update of a structural database dedicated to orthosteric modulation of protein–protein interactions
Marie-Jeanne Basse
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Stéphane Betzi
,
Xavier Morelli
,
Philippe Roche
Journal articles
hal-01307114v1
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Pre-B cell receptor binding to galectin-1 modifies galectin-1/carbohydrate affinity to modulate specific galectin-1/glycan lattice interactions
Jeremy Bonzi
,
Olivier Bornet
,
Stéphane Betzi
,
Brian T Kasper
,
Lara K Mahal
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et al.
Journal articles
hal-02018118v1
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Genetic, structural, and chemical insights into the dual function of GRASP55 in germ cell Golgi remodeling and JAM-C polarized localization during spermatogenesis
Amandine Cartier-Michaud
,
Anne-Laure Bailly
,
Stéphane Betzi
,
Xiaoli Shi
,
Jean-Claude Lissitzky
,
et al.
Journal articles
hal-01542697v1
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Discovery of Small-Molecule Inhibitors of the PTK7/β-Catenin Interaction Targeting the Wnt Signaling Pathway in Colorectal Cancer
Laetitia Ganier
,
Stéphane Betzi
,
Carine Derviaux
,
Philippe Roche
,
Charlotte Dessaux
,
et al.
Journal articles
hal-03817750v1
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In silico molecular target prediction unveils mebendazole as a potent MAPK14 inhibitor
Jeremy Ariey‐bonnet
,
Kendall Carrasco
,
Marion Le Grand
,
Laurent Hoffer
,
Stéphane Betzi
,
et al.
Journal articles
hal-02989358v1
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Accelerating small compounds discovery targeting protein-protein interaction
S. Milhas
,
S. Betzi
,
P. Roche
,
M. Cholay
,
A. Restouin
,
et al.
FEBS Journal, 2015, 282 (1, SI), pp.134
Journal articles
hal-01439038v1
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Discovery of a PDZ Domain Inhibitor Targeting the Syndecan/Syntenin Protein–Protein Interaction: A Semi-Automated “Hit Identification-to-Optimization” Approach
Laurent Hoffer
,
Manon Garcia
,
Raphael Leblanc
,
Mikael Feracci
,
Stéphane Betzi
,
et al.
Journal articles
hal-04048842v1
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Stereoselective synthesis of original spirolactams displaying promising folded structures.
Guilhem Chaubet
,
Thibault Coursindel
,
Xavier Morelli
,
Stéphane Betzi
,
Philippe Roche
,
et al.
Journal articles
hal-00871067v1
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CRCM5484: A BET- BDII Selective Compound With Differential Anti-Leukemic Drug Modulation
Kendall Carrasco
,
Camille Montersino
,
Carine Derviaux
,
Magali Saez-Ayala
,
Laurent Hoffer
,
et al.
Journal articles
hal-03624836v1
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Structural and Biochemical Characterization of the Cop9 Signalosome CSN5/CSN6 Heterodimer
Melissa Birol
,
Radoslav Ivanov Enchev
,
André Padilla
,
Florian Stengel
,
Ruedi Aebersold
,
et al.
Journal articles
hal-03726696v1
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Protein protein interaction inhibition (2P2I) combining high throughput and virtual screening: Application to the HIV-1 Nef protein.
Stéphane Betzi
,
Audrey Restouin
,
Sandrine Opi
,
Stefan T Arold
,
Isabelle Parrot
,
et al.
Proceedings of the National Academy of Sciences of the United States of America, 2007, 104 (49), pp.19256-61. ⟨10.1073/pnas.0707130104⟩
Journal articles
hal-00473817v1
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Structural recognition mechanisms between human Src homology domain 3 (SH3) and ALG-2-interacting protein X (Alix)
Xiaoli Shi
,
Stéphane Betzi
,
Adrien Lugari
,
Sandrine Opi
,
Audrey Restouin
,
et al.
Journal articles
hal-00717171v1
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Coronavirus Nsp10, a critical co-factor for activation of multiple replicative enzymes
Mickaël Bouvet
,
Adrien Lugari
,
Clara C. Posthuma
,
Jessika C. Zevenhoven
,
Stéphanie Bernard
,
et al.
Journal articles
hal-01910944v1
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Dual protein kinase and nucleoside kinase modulators for rationally designed polypharmacology
Kahina Hammam
,
Magali Saez-Ayala
,
Etienne Rebuffet
,
Laurent Gros
,
Sophie Lopez
,
et al.
Journal articles
hal-01643359v1
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Revisiting the molecular interactions between the tumor protein TCTP and the drugs sertraline/thioridazine.
Florian Malard
,
Eric Jacquet
,
Naima Nhiri
,
Christina Sizun
,
Amélie Chabrier
,
et al.
Journal articles
hal-03370569v2
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Antimicrobial and cytotoxic effects of marine sponge extracts Agelas clathrodes, Desmapsamma anchorata and Verongula rigida from a Caribbean Island
Julie Piron
,
Stéphane Betzi
,
Jessica Pastour
,
Audrey Restouin
,
Remy Castellano
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et al.
Journal articles
hal-03803766v1
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Crystal structure of the vaccinia virus DNA polymerase holoenzyme subunit D4 in complex with the A20 N-terminal domain
Céline Contesto-Richefeu
,
Nicolas Tarbouriech
,
Xavier Brazzolotto
,
Stéphane Betzi
,
Xavier Morelli
,
et al.
Journal articles
hal-01132360v1
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Mutational phospho-mimicry reveals a regulatory role for the XRCC4 and XLF C-terminal tails in modulating DNA bridging during classical non-homologous end joining
Davide Normanno
,
Aurélie Négrel
,
Abinadabe J de Melo
,
Stéphane Betzi
,
Katheryn Meek
,
et al.
Journal articles
hal-01541119v1
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Pharmacological inhibition of syntenin PDZ2 domain impairs breast cancer cell activities and exosome loading with syndecan and EpCAM cargo
R. Leblanc
,
R. Kashyap
,
K. Barral
,
A.L. Egea‐jimenez
,
D. Kovalskyy
,
et al.
Journal articles
hal-03152593v1
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Identification of allosteric inhibitors blocking the hepatitis C virus polymerase NS5B in the RNA synthesis initiation step.
Stéphane Betzi
,
Cécilia Eydoux
,
Cécile Bussetta
,
Marilyne Blemont
,
Pieter Leyssen
,
et al.
Journal articles
istex
hal-00418783v1
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GFscore: a general nonlinear consensus scoring function for high-throughput docking.
Stéphane Betzi
,
Karsten Suhre
,
Bernard Chétrit
,
Françoise Guerlesquin
,
Xavier Morelli
Journal articles
istex
hal-00475665v1
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