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Multicenter prospective randomized study comparing the technique of using a bovine pericardium biological prosthesis reinforcement in parietal herniorrhaphy (Tutomesh TUTOGEN) with simple parietal herniorrhaphy, in a potentially contaminated setting

Marius Nedelcu , Pierre Verhaeghe , Mehdi Skalli , Gerard Champault , Christophe Barrat , et al.
Wound Repair and Regeneration: Official Publication of the Wound Healing Society [and] the European Tissue Repair Society, 2016, 24 (2), p. 427-433. ⟨10.1111/wrr.12386⟩
Journal articles istex hal-01474696v1
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Synthesis and in vitro evaluation of 4-trichloromethylpyrrolo[1,2-a]quinoxalines as new antiplasmodial agents

Nicolas Primas , Peggy Suzanne , Pierre Verhaeghe , Sébastien Hutter , Charline Kieffer , et al.
European Journal of Medicinal Chemistry, 2014, 83, pp.26-35. ⟨10.1016/j.ejmech.2014.06.014⟩
Journal articles hal-01417058v1
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Discovery of new hit-molecules targeting Plasmodium falciparum through a global SAR study of the 4-substituted-2-trichloromethylquinazoline antiplasmodial scaffold

Justine Desroches , Charline Kieffer , Nicolas Primas , Sébastien Hutter , Armand Gellis , et al.
European Journal of Medicinal Chemistry, 2017, 125 (128), pp.68-86. ⟨10.1016/j.ejmech.2016.09.029⟩
Journal articles hal-01416990v1

Preventing the contamination of hospital personnel by cytotoxic agents: evaluation and training of the para-professional healthcare workers in oncology units

C. Kieffer , Pierre Verhaeghe , S. Lagrassa , R. Gregoire , Z. Moussaoui , et al.
European Journal of Cancer Care, 2015, 24 (3), pp.404-410. ⟨10.1111/ecc.12249⟩
Journal articles istex hal-01460563v1
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Anticancer and anti-inflammatory activities of some new pyrazolo[3,4-b]pyrazines

Hussein El-Kashef , Talaat El-Emary , Pierre Verhaeghe , P. Vanelle , Maha Samy
Molecules, 2018, 23 (10), pp.2657. ⟨10.3390/molecules23102657⟩
Journal articles hal-01954194v1
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4-Substituted Thieno[3,2-d]pyrimidines as Dual-Stage Antiplasmodial Derivatives

Prisca Lagardère , Romain Mustière , Nadia Amanzougaghene , Sébastien Hutter , Jean-François Franetich , et al.
Pharmaceuticals, 2022, 15 (7), pp.820. ⟨10.3390/ph15070820⟩
Journal articles hal-03725749v1

Safety Review: Squalene and Thimerosal in Vaccines

Marc Montana , Pierre Verhaeghe , Caroline Ducros , Thierry Terme , Patrice Vanelle , et al.
Thérapie, 2010, 65 (6), pp.533--541. ⟨10.2515/therapie/2010069⟩
Journal articles istex hal-01460254v1

Discovery of new thienopyrimidinone derivatives displaying antimalarial properties toward both erythrocytic and hepatic stages of Plasmodium

Anita Cohen , Peggy Suzanne , Jean-Charles Lancelot , Pierre Verhaeghe , Aurélien Lesnard , et al.
European Journal of Medicinal Chemistry, 2015, 95, pp.16-28. ⟨10.1016/j.ejmech.2015.03.011⟩
Journal articles hal-01460555v1

8-Aryl-6-chloro-3-nitro-2-(phenylsulfonylmethyl)imidazo[1,2-a]pyridines as potent antitrypanosomatid molecules bioactivated by type 1 nitroreductases

Cyril Fersing , Clotilde Boudot , Julien Pedron , Sébastien Hutter , Nicolas Primas , et al.
European Journal of Medicinal Chemistry, 2018, 157, pp.115-126. ⟨10.1016/j.ejmech.2018.07.064⟩
Journal articles hal-01909649v1

New nitroaromatic candidats for trypanosomiasis therapeutics.

Clotilde Boudot , Cyril Fersing , Julien Pedron , Valere Belle Mbou , Caroline Castera-Ducros , et al.
Congress ICOPA (14th International Congress of Parasitology), Aug 2018, Daegu, South Korea
Poster communications hal-01936829v1

Synthèse et évaluations biologiques de nouvelles 8-nitroquinoléin-2(1H)-ones antiparisitaires.

Julien Pedron , Clotilde Boudot , Sebastien Hutter , Sandra Bourgeade-Delmas , Lucie Paloque , et al.
8èmes Journées du Consortium anti-Parasitaires et anti-Fongique (CaPF), Mar 2018, Lyon, France
Conference papers hal-01939612v1

Albumin-Bound Paclitaxel: The Benefit of This New Formulation in the Treatment of Various Cancers

M. Montana , C. Ducros , P. Verhaeghe , T. Terme , P. Vanelle , et al.
Journal of Chemotherapy, 2011, 23 (2), pp.59--66
Journal articles hal-01460327v1
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Synthetic Polypeptide Polymers as Simplified Analogues of Antimicrobial Peptides

Pedro Salas-Ambrosio , Antoine Tronnet , Pierre Verhaeghe , Colin Bonduelle
Biomacromolecules, 2021, 22 (1), pp.57-75. ⟨10.1021/acs.biomac.0c00797⟩
Journal articles hal-02931945v1

Discovery of a new antileishmanial hit in 8-nitroquinoline series

Lucie Paloque , Pierre Verhaeghe , Magali Casanova , Caroline Castera-Ducros , Aurélien Dumètre , et al.
European Journal of Medicinal Chemistry, 2012, 54, pp.75-86
Journal articles hal-02049707v1
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A new DMAP-catalyzed and microwave-assisted approach for introducing heteroarylamino substituents at position 4 of the quinazoline ring.

Armand Gellis , Charline Kieffer , Nicolas Primas , Gilles Lanzada , Michel Giorgi , et al.
Tetrahedron, 2014, 78 (44), pp.8257-8266. ⟨10.1016/j.tet.2014.09.024⟩
Journal articles hal-01417081v1

Synthesis of antiplasmodial 2-aminothieno[3,2-d]pyrimidin-4(3H)-one analogues using the scaffold hopping strategy

Romain Mustière , Prisca Lagardère , Sébastien Hutter , Viviana Dell’orco , Nadia Amanzougaghene , et al.
European Journal of Medicinal Chemistry, 2022, 241, pp.114619. ⟨10.1016/j.ejmech.2022.114619⟩
Journal articles hal-03737417v1

Highly efficient microwave assisted α-trichlorination reaction of α-methylated nitrogen containing heterocycles

P. Verhaeghe , P. Rathelot , A. Gellis , S. Rault , P. Vanelle
Tetrahedron, 2006, 62, pp.8173-8176
Journal articles hal-00096229v1
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Antiplasmodial 2-thiophenoxy-3-trichloromethyl quinoxalines target the apicoplast of Plasmodium falciparum

Dyhia Amrane , Nicolas Primas , Christophe-Sébastien Arnold , Sébastien Hutter , Béatrice Louis , et al.
European Journal of Medicinal Chemistry, 2021, 224, pp.113722. ⟨10.1016/j.ejmech.2021.113722⟩
Journal articles hal-03323972v1
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Antitrypanosomatid Pharmacomodulation at Position 3 of the 8-Nitroquinolin-2(1 H)-one Scaffold Using Palladium-Catalysed Cross-Coupling Reactions

Julien Pedron , Clotilde Boudot , Sandra Bourgeade-Delmas , Alix Sournia-Saquet , Lucie Paloque , et al.
ChemMedChem, 2018, 13 (20), pp.2217-2228. ⟨10.1002/cmdc.201800456⟩
Journal articles hal-01888530v1

Antileishmanial pharmacomodulation in 8-nitroquinolin-2(1H)-one series

Charline Kieffer , Anita Cohen , Pierre Verhaeghe , Lucie Paloque , Sébastien Hutter , et al.
Bioorganic and Medicinal Chemistry, 2015, 23 (10), pp.2377-2386. ⟨10.1016/j.bmc.2015.03.064⟩
Journal articles hal-01460646v1

Using the Sonogashira Reaction for Preparing a New Fragment Library based on the 3-alkynylimidazo[1,2-alpha] pyridine Scaffold

Caroline Castera-Ducros , Hussein El-Kashef , Melanie Piednoel , Vincent Remusat , Jean-Claude Teulade , et al.
Letters in Organic Chemistry, 2016, 13 (7), pp.519-525. ⟨10.2174/1570178613666160919124456⟩
Journal articles hal-01460673v1

Tandem synthesis and in vitro antiplasmodial evaluation of new naphtho[2,1-d] thiazole derivatives

Anita D Cohen , Pierre Verhaeghe , Maxime D. Crozet , Sébastien Hutter , Pascal Rathelot , et al.
European Journal of Medicinal Chemistry, 2012, 55, pp.315--324. ⟨10.1016/j.ejmech.2012.07.034⟩
Journal articles istex hal-01460344v1
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Looking for new antiplasmodial quinazolines: DMAP-catalyzed synthesis of 4-benzyloxy- and 4-aryloxy-2-trichloromethylquinazolines and their in vitro evaluation toward Plasmodium falciparum

Armand Gellis , Nicolas Primas , Sébastien Hutter , Gilles Lanzada , Vincent Remusat , et al.
European Journal of Medicinal Chemistry, 2016, 119, pp.34-44. ⟨10.1016/j.ejmech.2016.04.059⟩
Journal articles hal-01417007v1

The Renewal of Interest in Nitroaromatic Drugs: Towards New Anti-Kinetoplastid Agents

Nicolas Primas , Caroline Ducros , Patrice Vanelle , Pierre Verhaeghe
Venkatesan Jayaprakash; Daniele Castagnolo; Yusuf Özkay. Medicinal Chemistry of Neglected and Tropical Diseases. Advances in the Design and Synthesis of Antimicrobial Agents, CRC Press, pp.250-280, 2019, 978-1-138-54124-5
Book sections hal-02923853v1
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Access to Original Vinylic Chlorides in the Quinazoline Series via a Monoelectronic Transfer Reaction Approach

Martine Maillard-Boyer , Caroline Castera-Ducros , Pierre Verhaeghe , France Sifredi , Pascal Rathelot , et al.
Molecules, 2010, 15 (4), pp.2719--2729. ⟨10.3390/molecules15042719⟩
Journal articles hal-01460257v1
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New 8-Nitroquinolinone Derivative Displaying Submicromolar in Vitro Activities against Both Trypanosoma brucei and cruzi

Julien Pedron , Clotilde Boudot , Jean-Yves Brossas , Emilie Pinault , Sandra Bourgeade-Delmas , et al.
ACS Medicinal Chemistry Letters, 2020, 11 (4), pp.464-472. ⟨10.1021/acsmedchemlett.9b00566⟩
Journal articles hal-02476867v1
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Synthesis and Antiplasmodial Evaluation of 4-Carboxamido- and 4-Alkoxy-2-trichloromethyl Quinazolines

Dyhia Amrane , Armand Gellis , Sebastien Hutter , Marion Prieri , Pierre Verhaeghe , et al.
Molecules, 2020, 25 (17), pp.3929. ⟨10.3390/molecules25173929⟩
Journal articles hal-02924455v1

Enteric pathogenic bacteria and resistance gene carriage in the homeless population in Marseille, France

Tran Duc Anh Ly , Linda Hadjadj , van Thuan Hoang , Ndiaw Goumbala , Thi Loi Dao , et al.
Acta Microbiologica et Immunologica Hungarica, 2021, 68 (1), pp.7-13. ⟨10.1556/030.2021.01346⟩
Journal articles hal-03280482v1

Ionic polypeptide polymers with unusual β-sheet stability

Michel Nguyen , Jean-Luc Stigliani , Christian Bijani , Pierre Verhaeghe , G. Pratviel , et al.
Biomacromolecules, 2018, 19 (10), pp.4068-4074. ⟨10.1021/acs.biomac.8b01084⟩
Journal articles hal-01954190v1
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Regioselective Suzuki-Miyaura Reaction: Application to the Microwave-promoted Synthesis of 4,7-Diarylquinazolines

Youssef Kabri , Pierre Verhaeghe , Armand Gellis , Patrice Vanelle
Molecules, 2010, 15 (5), pp.2949--2961. ⟨10.3390/molecules15052949⟩
Journal articles hal-01460231v1