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An Engineered Human Fc variant With Exquisite Selectivity for FcγRIIIaV158 Reveals That Ligation of FcγRIIIa Mediates Potent Antibody Dependent Cellular Phagocytosis With GM-CSF-Differentiated Macrophages

Tae Hyun Kang , Chang-Han Lee , George Delidakis , Jiwon Jung , Odile Richard-Le Goff , et al.
Frontiers in Immunology, 2019, 10, pp.562. ⟨10.3389/fimmu.2019.00562⟩
Journal articles pasteur-02448640v1
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An Engineered Human Fc Domain that Behaves like a pH-Toggle Switch for Ultra-Long Circulation Persistence

Tae Hyun Kang , Chang-Han Lee , Tae Hyun Kang , Ophélie Godon , Makiko Watanabe , et al.
Nature Communications, 2019, 10 (1), pp.5031. ⟨10.1038/s41467-019-13108-2⟩
Journal articles pasteur-02448624v1
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Microbiota-induced tertiary lymphoid tissues aggravate inflammatory disease in the absence of RORγt and LTi cells

Matthias Lochner , Caspar Ohnmacht , Laura Presley , Pierre Bruhns , Mustapha Si-Tahar , et al.
Journal of Experimental Medicine, 2011, 208 (1), pp.125 - 134. ⟨10.1084/jem.20100052⟩
Journal articles pasteur-01402751v1
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Comment on “Tumor-initiating cells establish an IL-33–TGF-β niche signaling loop to promote cancer progression”

Jasper B J Kamphuis , William P M Worrall , Julien Stackowicz , Aurélie Mougel , Emilie Mauré , et al.
Science, 2021, 372 (6538), pp.eabf2022. ⟨10.1126/science.abf2022⟩
Journal articles pasteur-03242901v1

Cutting Edge: Neutralizing Public Antibody Responses Are an Ancient Form of Defense Conserved in Fish and Mammals

Rosario Castro , Sofie Navelsaker , Bertrand Collet , Luc Jouneau , Pascal Bochet , et al.
Journal of Immunology, 2021, 207 (2), pp.371-375. ⟨10.4049/jimmunol.2100149⟩
Journal articles hal-03327860v1

The SH2 domain containing inositol 5-phosphatase SHIP2 associates to the immunoreceptor tyrosine-based inhibition motif of FcγRIIB in B cells under negative signaling

E Muraille , Pierre Bruhns , X Pesesse , Marc Daëron , C Erneux
Immunology Letters, 2000, 72 (1), pp.7-15. ⟨10.1016/s0165-2478(00)00162-0⟩
Journal articles istex pasteur-03243055v1

Differential roles of N- and C-terminal immunoreceptor tyrosine-based inhibition motifs during inhibition of cell activation by killer cell inhibitory receptors.

Pierre Bruhns , Philippe Marchetti , Wolf Fridman , E Vivier , Marc Daëron
Journal of Immunology, 1999, 162 (6), pp.3168-75
Journal articles pasteur-03243064v1
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The anti-IgE mAb Omalizumab induces adverse reactions by engaging Fcγ receptors

Bianca Balbino , Pauline Herviou , Ophélie Godon , Julien Stackowicz , Odile Richard-Le Goff , et al.
Journal of Clinical Investigation, 2019, ⟨10.1172/JCI129697⟩
Journal articles pasteur-02451133v1

Human FcγRIIA induces anaphylactic and allergic reactions

Friederike Jönsson , David Mancardi , Wei Zhao , Yoshihiro Kita , Bruno Iannascoli , et al.
Blood, 2012, 119 (11), pp.2533-2544. ⟨10.1182/blood-2011-07-367334⟩
Journal articles pasteur-02533059v1
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Human IgG1 antibodies suppress angiogenesis in a target-independent manner.

Sasha Bogdanovich , Younghee Kim , Takeshi Mizutani , Reo Yasuma , Laura Tudisco , et al.
Signal Transduction and Targeted Therapy, 2016, 1, pp.15001. ⟨10.1038/sigtrans.2015.1⟩
Journal articles pasteur-02511158v1
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Qualitative monitoring of SARS-CoV-2 mRNA vaccination in humans using droplet microfluidics

Matteo Broketa , Aurélien Sokal , Michael Mor , Pablo Canales-Herrerias , Angga Perima , et al.
JCI Insight, 2023, In press. ⟨10.1172/jci.insight.166602⟩
Journal articles pasteur-04111772v1
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The SH2 domain-containing inositol 5-phosphatase SHIP1 is recruited to the intracytoplasmic domain of human FcgammaRIIB and is mandatory for negative regulation of B cell activation.

Isabelle Isnardi , Pierre Bruhns , Georges Bismuth , Wolf H Fridman , Marc Daëron
Immunology Letters, 2006, 104 (1-2), pp.156-65. ⟨10.1016/j.imlet.2005.11.027⟩
Journal articles pasteur-00270018v1
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Regulation of allergy by Fc receptors.

Pierre Bruhns , Sophie Frémont , Marc Daëron
Current Opinion in Immunology, 2005, 17 (6), pp.662-9. ⟨10.1016/j.coi.2005.09.012⟩
Journal articles pasteur-00270046v1
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Molecular Basis of the Recruitment of the SH2 Domain-containing Inositol 5-Phosphatases SHIP1 and SHIP2 by FcγRIIB

Pierre Bruhns , Frédéric Vély , Odile Malbec , Wolf Fridman , Eric Vivier , et al.
Journal of Biological Chemistry, 2000, 275 (48), pp.37357-37364. ⟨10.1074/jbc.M003518200⟩
Journal articles pasteur-03243045v1
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The Pseudo-immunoreceptor Tyrosine-based Activation Motif of CD5 Mediates Its Inhibitory Action on B-cell Receptor Signaling

Hélène Gary-Gouy , Pierre Bruhns , Christian Schmitt , Ali Dalloul , Marc Daëron , et al.
Journal of Biological Chemistry, 2000, 275 (1), pp.548-556. ⟨10.1074/jbc.275.1.548⟩
Journal articles pasteur-03243059v1
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Single-Cell Technologies for the Study of Antibody-Secreting Cells

Matteo Broketa , Pierre Bruhns
Frontiers in Immunology, 2022, 12, pp.821729. ⟨10.3389/fimmu.2021.821729⟩
Journal articles hal-03582460v1

Neutrophils in local and systemic antibody-dependent inflammatory and anaphylactic reactions

Friederike Jönsson , David A. Mancardi , Marcello Albanesi , Pierre Bruhns
Journal of Leukocyte Biology, 2013, 94 (4), pp.643-656. ⟨10.1189/jlb.1212623⟩
Journal articles pasteur-02578044v1
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Src Homology 2 Domain-containing Inositol 5-Phosphatase 1 Mediates Cell Cycle Arrest by FcγRIIB

Odile Malbec , Christian Schmitt , Pierre Bruhns , Gerald Krystal , Wolf Fridman , et al.
Journal of Biological Chemistry, 2001, 276 (32), pp.30381-30391. ⟨10.1074/jbc.M011094200⟩
Journal articles pasteur-03243043v1

Platelet homeostasis is regulated by platelet expression of CD47 under normal conditions and in passive immune thrombocytopenia

Mattias Olsson , Pierre Bruhns , William Frazier , Jeffrey Ravetch , Per-Arne Oldenborg
Blood, 2005, 105 (9), pp.3577-3582. ⟨10.1182/blood-2004-08-2980⟩
Journal articles pasteur-03242942v1

Cutting Edge: The Murine High-Affinity IgG Receptor FcγRIV Is Sufficient for Autoantibody-Induced Arthritis

David Mancardi , Friederike Jönsson , Bruno Iannascoli , Huot Khun , Nico van Rooijen , et al.
Journal of Immunology, 2011, 186 (4), pp.1899-1903. ⟨10.4049/jimmunol.1003642⟩
Journal articles pasteur-02533277v1

A Strain of Lactobacillus casei Inhibits the Effector Phase of Immune Inflammation.

Cécile Schiffer , Ana Inés Lalanne , Lydie Cassard , David Mancardi , Odile Malbec , et al.
Journal of Immunology, 2011, 187 (5), pp.2646-2655. ⟨10.4049/jimmunol.1002415⟩
Journal articles pasteur-02533129v1
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Specificity of mouse and human Fcgamma receptors and their polymorphic variants for IgG subclasses of different species

Yu Wang , Vanessa Krémer , Bruno Iannascoli , Odile Richard Le Goff , David A Mancardi , et al.
European Journal of Immunology, 2022, ⟨10.1002/eji.202149766⟩
Journal articles pasteur-03566563v1
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In vivo effector functions of high-affinity mouse IgG receptor FcγRI in disease and therapy models

Caitlin M. Gillis , Priscila P. Zenatti , David A. Mancardi , Héloïse Beutier , Laurence Fiette , et al.
Journal of Autoimmunity, 2017, 80, pp.95-102. ⟨10.1016/j.jaut.2016.09.009⟩
Journal articles pasteur-01388794v1
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Shaping mycolactone for therapeutic use against inflammatory disorders

Laure Guenin-Mace , Ludivine Baron , Anne-Caroline Chany , Cédric Tresse , Sarah Saint-Auret , et al.
Science Translational Medicine, 2015, 7 (289), pp.289ra85 - 289ra85. ⟨10.1126/scitranslmed.aab0458⟩
Journal articles pasteur-01382767v1
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Innate Immune Basis for Rift Valley Fever Susceptibility in Mouse Models

Rashida Lathan , Dominique Simon-Chazottes , Grégory Jouvion , Ophélie Godon , Marie Malissen , et al.
Scientific Reports, 2017, 7 (1), pp.7096. ⟨10.1038/s41598-017-07543-8⟩
Journal articles pasteur-01684520v1
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Omicron BA.1 breakthrough infection drives long-term remodeling of the memory B cell repertoire in vaccinated individuals

Aurélien Sokal , Giovanna Barba-Spaeth , Lise Hunault , Ignacio Fernández , Matteo Broketa , et al.
Preprints, Working Papers, ... pasteur-03986461v1

Differential Recruitment of Activating and Inhibitory FcγRII during Phagocytosis.

Sujata Syam , Patricia Mero , Theodore Pham , Courtney Mcintosh , Pierre Bruhns , et al.
Journal of Immunology, 2010, 184 (6), pp.2966-2973. ⟨10.4049/jimmunol.0900016⟩
Journal articles pasteur-02533294v1

Autonomous phagosomal degradation and antigen presentation in dendritic cells.

Eik Hoffmann , Fiorella Kotsias , Geraldine Visentin , Pierre Bruhns , Ariel Savina , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2012, 109 (36), pp.14556-14561. ⟨10.1073/pnas.1203912109⟩
Journal articles pasteur-02518790v1

A hypomorphic mutation in the Gfi1 transcriptional repressor results in a novel form of neutropenia

Diana Ordoñez-Rueda , Friederike Jönsson , David Mancardi , Weidong Zhao , Aurélie Malzac , et al.
European Journal of Immunology, 2012, 42 (9), pp.2395-2408. ⟨10.1002/eji.201242589⟩
Journal articles pasteur-02518924v1

Intravenous immunoglobulin promotes antitumor responses by modulating macrophage polarization.

Angeles Domínguez-Soto , Mateo de Las Casas-Engel , Rafael Bragado , José Medina-Echeverz , Laura Aragoneses-Fenoll , et al.
Journal of Immunology, 2014, 193 (10), pp.5181-5189. ⟨10.4049/jimmunol.1303375⟩
Journal articles pasteur-02512274v1