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Targeting Oxidative Stress With Auranofin or Prima-1Met to Circumvent p53 or Bax/Bak Deficiency in Myeloma Cells
Benoit Tessoulin
,
Géraldine Descamps
,
Christelle Dousset
,
Martine Amiot
,
Catherine Pellat-Deceunynck
et al.
Journal articles
inserm-02055153v1
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p53 regulates CD46 expression and measles virus infection in myeloma cells
Anne Lok
,
Géraldine Descamps
,
Benoit Tessoulin
,
David Chiron
,
Marion Eveillard
et al.
Journal articles
inserm-01957487v1
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Toll-like receptors: lessons to learn from normal and malignant human B cells
David Chiron
,
Isabelle Bekeredjian-Ding
,
Catherine Pellat-Deceunynck
,
Régis Bataille
,
Gaetan Jego
et al.
Journal articles
inserm-02459027v1
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Differential expression of Bcl-2 in human plasma cell disorders according to proliferation status and malignancy
Denis Puthier
,
Catherine Pellat-Deceunynck
,
S. Barille
,
N. Robillard
,
M. J. Rapp
et al.
Leukemia, 1999, 13 (2), pp.289--294
Journal articles
hal-01595832v1
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RITA (Reactivating p53 and Inducing Tumor Apoptosis) is efficient against TP53 abnormal myeloma cells independently of the p53 pathway
Sylvanie Surget
,
Géraldine Descamps
,
Carole Brosseau
,
Vincent Normant
,
Sophie Maïga
et al.
Journal articles
inserm-03290484v1
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The origin of the plasma-cell heterogeneity
Catherine Pellat-Deceunynck
,
Thierry Defrance
Frontiers in Immunology, 2015, 6
Journal articles
inserm-01820475v1
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Generation and characterization of novel anti-DR4 and anti-DR5 antibodies developed by genetic immunization
Agathe Dubuisson
,
Cécile Favreau
,
Eric Fourmaux
,
Sabrina Lareure
,
Rafael Rodrigues-Saraiva
et al.
Journal articles
inserm-02006230v1
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BH3 profiling as a tool to identify acquired resistance to venetoclax in multiple myeloma
Christelle Dousset
,
Sophie Maïga
,
Patricia Gomez-Bougie
,
Joy Le Coq
,
Cyrille Touzeau
et al.
Journal articles
inserm-01353369v1
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p53 dysregulation in B-cell malignancies: More than a single gene in the pathway to hell
Benoit Tessoulin
,
Marion Eveillard
,
Anne Lok
,
David Chiron
,
Philippe Moreau
et al.
Journal articles
inserm-01493742v1
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Curcumin induces cell death of the main molecular myeloma subtypes, particularly the poor prognosis subgroups
Patricia Gomez-Bougie
,
Maxime Halliez
,
Sophie Maïga
,
Catherine Godon
,
Charlotte Kervoëlen
et al.
Journal articles
inserm-02534388v1
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Biological rational for sequential targeting of Bruton tyrosine kinase and Bcl-2 to overcome CD40-induced ABT-199 resistance in mantle cell lymphoma
David Chiron
,
Christelle Dousset
,
Carole Brosseau
,
Cyrille Touzeau
,
Sophie Maïga
et al.
Journal articles
inserm-02534385v1
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Decitabine and Melphalan Fail to Reactivate p73 in p53 Deficient Myeloma Cells
Pierre-Samuel Gillardin
,
Géraldine Descamps
,
Sophie Maiga
,
Benoit Tessoulin
,
Hanane Djamai
et al.
Journal articles
inserm-01691503v1
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Dual targeting of BCL2 and MCL1 rescues myeloma cells resistant to BCL2 and MCL1 inhibitors associated with the formation of BAX/ BAK hetero-complexes
Carolane Seiller
,
Sophie Maiga
,
Cyrille Touzeau
,
Céline Bellanger
,
Charlotte Kervoëlen
et al.
Journal articles
inserm-02563554v1
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Heat shock factor 1 is a potent therapeutic target for enhancing the efficacy of treatments for multiple myeloma with adverse prognosis
Sophie Bustany
,
Julie Cahu
,
Géraldine Descamps
,
Catherine Pellat-Deceunynck
,
Brigitte Sola
et al.
Journal articles
inserm-01237704v1
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CSF1R and BTK inhibitions as novel strategies to disrupt the dialogue between mantle cell lymphoma and macrophages
Antonin Papin
,
Benoit Tessoulin
,
Céline Bellanger
,
Anne Moreau
,
Yannick Le Bris
et al.
Leukemia, In press, Epub ahead of print
Journal articles
inserm-02081007v1
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Whole-exon sequencing of human myeloma cell lines shows mutations related to myeloma patients at relapse with major hits in the DNA regulation and repair pathways
Benoit Tessoulin
,
Agnès Moreau-Aubry
,
Géraldine Descamps
,
Patricia Gomez-Bougie
,
Sophie Maiga
et al.
Journal articles
inserm-01958772v1
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The REFRACT-LYMA cohort study: a French observational prospective cohort study of patients with mantle cell lymphoma
Matthieu Hanf
,
David Chiron
,
Sophie de Visme
,
Cyrille Touzeau
,
Hervé Maisonneuve
et al.
Journal articles
inserm-01381110v1
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Myeloma Cell Self-Renewal Depends on JAG2 Expression and Is Mediated by IGF1 or SCF Loop
David Chiron
,
Sophie Maiga
,
Géraldine Descamps
,
Severine Marionneau-Lambot
,
Catherine Pellat-Deceunynck
et al.
Conference papers
inserm-02459063v1
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Emergence and evolution of TP53 mutations are a key feature of disease progression in myelodysplastic patients with lower-risk del(5q) treated with lenalidomide.
Laurence Lodé
,
Audrey Ménard
,
Laurent Flet
,
Steven Richebourg
,
Marion Loirat
et al.
Journal articles
inserm-01691580v1
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TRAIL receptor gene editing unveils TRAIL-R1 as a master player of apoptosis induced by TRAIL and ER stress
Florent Dufour
,
Thibault Rattier
,
Andrei Alexandru Constantinescu
,
Luciana Zischler
,
Aymeric Morlé
et al.
Journal articles
inserm-01423110v1
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A high-risk signature for patients with multiple myeloma established from the molecular classification of human myeloma cell lines.
Jérôme Moreaux
,
Bernard Klein
,
Régis Bataille
,
Géraldine Descamps
,
Sophie Maïga
et al.
Journal articles
inserm-00550232v1
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BH3-mimetic toolkit guides the respective use of BCL2 and MCL1 BH3-mimetics in myeloma treatment
Patricia Gomez-Bougie
,
Sophie Maïga
,
Benoit Tessoulin
,
Jessie Bourcier
,
Antoine Bonnet
et al.
Journal articles
inserm-01900681v1
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The MYRACLE protocol study: a multicentric observational prospective cohort study of patients with multiple myeloma
Lina Benaniba
,
Benoit Tessoulin
,
Sabrina Trudel
,
Catherine Pellat-Deceunynck
,
Martine Amiot
et al.
Journal articles
inserm-02290127v1
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A simple flow cytometry-based barcode for routine authentication of multiple myeloma and mantle cell lymphoma cell lines
Sophie Maiga
,
Carole Brosseau
,
Géraldine Descamps
,
Christelle Dousset
,
Patricia Gomez-Bougie
et al.
Journal articles
inserm-02100586v1
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Dexamethasone-induced cell death is restricted to specific molecular subgroups of multiple myeloma
Charlotte Kervoëlen
,
Emmanuelle Ménoret
,
Patricia Gomez-Bougie
,
Régis Bataille
,
Catherine Godon
et al.
Journal articles
inserm-01817581v1
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The selectivity of Marinopyrrole A to induce apoptosis in MCL1 high BCL2 low expressing myeloma cells is related to its ability to impair protein translation
Patricia Gomez-Bougie
,
Christelle Dousset
,
Géraldine Descamps
,
A. Schnitzler
,
Logan Audiger
et al.
Journal articles
inserm-01419215v1
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Rational targeted therapies to overcome microenvironment-dependent expansion of mantle cell lymphoma
David Chiron
,
Céline Bellanger
,
Antonin Papin
,
Benoit Tessoulin
,
Christelle Dousset
et al.
Journal articles
inserm-01405674v2
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Whole genome copy number analysis in search of new prognostic biomarkers in first line treatment of mantle cell lymphoma. A study by the LYSA group
Yannick Le Bris
,
Florence Magrangeas
,
Anne Moreau
,
David Chiron
,
Catherine Guérin-Charbonnel
et al.
Journal articles
inserm-02874026v1
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BCL2-Family Dysregulation in B-Cell Malignancies: From Gene Expression Regulation to a Targeted Therapy Biomarker
Benoit Tessoulin
,
Antonin Papin
,
Patricia Gomez-Bougie
,
Céline Bellanger
,
Martine Amiot
et al.
Journal articles
inserm-01990870v1
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The IL32/BAFF axis supports prosurvival dialogs in the lymphoma ecosystem and is disrupted by NIK inhibition
Salomé Decombis
,
Antonin Papin
,
Céline Bellanger
,
Clara Sortais
,
Christelle Dousset
et al.
Journal articles
inserm-03625695v1
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