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Targeting Oxidative Stress With Auranofin or Prima-1Met to Circumvent p53 or Bax/Bak Deficiency in Myeloma Cells

Benoit Tessoulin , Géraldine Descamps , Christelle Dousset , Martine Amiot , Catherine Pellat-Deceunynck et al.
Frontiers in Oncology, 2019, ⟨10.3389/fonc.2019⟩
Journal articles inserm-02055153v1
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p53 regulates CD46 expression and measles virus infection in myeloma cells

Anne Lok , Géraldine Descamps , Benoit Tessoulin , David Chiron , Marion Eveillard et al.
Blood Advances, 2018, 2 (23), pp.3492-3505. ⟨10.1182/bloodadvances.2018025106⟩
Journal articles inserm-01957487v1

Toll-like receptors: lessons to learn from normal and malignant human B cells

David Chiron , Isabelle Bekeredjian-Ding , Catherine Pellat-Deceunynck , Régis Bataille , Gaetan Jego et al.
Journal articles inserm-02459027v1

Differential expression of Bcl-2 in human plasma cell disorders according to proliferation status and malignancy

Denis Puthier , Catherine Pellat-Deceunynck , S. Barille , N. Robillard , M. J. Rapp et al.
Leukemia, 1999, 13 (2), pp.289--294
Journal articles hal-01595832v1
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RITA (Reactivating p53 and Inducing Tumor Apoptosis) is efficient against TP53 abnormal myeloma cells independently of the p53 pathway

Sylvanie Surget , Géraldine Descamps , Carole Brosseau , Vincent Normant , Sophie Maïga et al.
BMC Cancer, 2014, 14 (14), pp.437. ⟨10.1186/1471-2407-14-437⟩
Journal articles inserm-03290484v1
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The origin of the plasma-cell heterogeneity

Catherine Pellat-Deceunynck , Thierry Defrance
Frontiers in Immunology, 2015, 6
Journal articles inserm-01820475v1
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Generation and characterization of novel anti-DR4 and anti-DR5 antibodies developed by genetic immunization

Agathe Dubuisson , Cécile Favreau , Eric Fourmaux , Sabrina Lareure , Rafael Rodrigues-Saraiva et al.
Cell Death and Disease, 2019, 10 (2), Epub ahead of print. ⟨10.1038/s41419-019-1343-5⟩
Journal articles inserm-02006230v1
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BH3 profiling as a tool to identify acquired resistance to venetoclax in multiple myeloma

Christelle Dousset , Sophie Maïga , Patricia Gomez-Bougie , Joy Le Coq , Cyrille Touzeau et al.
British Journal of Haematology, 2016, [Epub ahead of print]. ⟨10.1111/bjh.14251⟩
Journal articles inserm-01353369v1
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p53 dysregulation in B-cell malignancies: More than a single gene in the pathway to hell

Benoit Tessoulin , Marion Eveillard , Anne Lok , David Chiron , Philippe Moreau et al.
Blood Reviews, 2017, [Epub ahead of print]. ⟨10.1016/j.blre.2017.03.001⟩
Journal articles inserm-01493742v1
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Curcumin induces cell death of the main molecular myeloma subtypes, particularly the poor prognosis subgroups

Patricia Gomez-Bougie , Maxime Halliez , Sophie Maïga , Catherine Godon , Charlotte Kervoëlen et al.
Cancer Biology and Therapy, 2015, 16 (1), pp.60-5. ⟨10.4161/15384047.2014.986997⟩
Journal articles inserm-02534388v1
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Biological rational for sequential targeting of Bruton tyrosine kinase and Bcl-2 to overcome CD40-induced ABT-199 resistance in mantle cell lymphoma

David Chiron , Christelle Dousset , Carole Brosseau , Cyrille Touzeau , Sophie Maïga et al.
Oncotarget, 2015, 6 (11), pp.8750-9. ⟨10.18632/oncotarget.3275⟩
Journal articles inserm-02534385v1
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Decitabine and Melphalan Fail to Reactivate p73 in p53 Deficient Myeloma Cells

Pierre-Samuel Gillardin , Géraldine Descamps , Sophie Maiga , Benoit Tessoulin , Hanane Djamai et al.
International Journal of Molecular Sciences, 2017, 19 (1), ⟨10.3390/ijms19010040⟩
Journal articles inserm-01691503v1
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Dual targeting of BCL2 and MCL1 rescues myeloma cells resistant to BCL2 and MCL1 inhibitors associated with the formation of BAX/ BAK hetero-complexes

Carolane Seiller , Sophie Maiga , Cyrille Touzeau , Céline Bellanger , Charlotte Kervoëlen et al.
Cell Death and Disease, 2020, 11, pp.316. ⟨10.1038/s41419-020-2505-1⟩
Journal articles inserm-02563554v1
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Heat shock factor 1 is a potent therapeutic target for enhancing the efficacy of treatments for multiple myeloma with adverse prognosis

Sophie Bustany , Julie Cahu , Géraldine Descamps , Catherine Pellat-Deceunynck , Brigitte Sola et al.
Journal of Hematology and Oncology, 2015, 8 (1), pp.40. ⟨10.1186/s13045-015-0135-3⟩
Journal articles inserm-01237704v1
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CSF1R and BTK inhibitions as novel strategies to disrupt the dialogue between mantle cell lymphoma and macrophages

Antonin Papin , Benoit Tessoulin , Céline Bellanger , Anne Moreau , Yannick Le Bris et al.
Leukemia, In press, Epub ahead of print
Journal articles inserm-02081007v1
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Whole-exon sequencing of human myeloma cell lines shows mutations related to myeloma patients at relapse with major hits in the DNA regulation and repair pathways

Benoit Tessoulin , Agnès Moreau-Aubry , Géraldine Descamps , Patricia Gomez-Bougie , Sophie Maiga et al.
Journal of Hematology and Oncology, 2018, 11 (1), pp.137. ⟨10.1186/s13045-018-0679-0⟩
Journal articles inserm-01958772v1
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The REFRACT-LYMA cohort study: a French observational prospective cohort study of patients with mantle cell lymphoma

Matthieu Hanf , David Chiron , Sophie de Visme , Cyrille Touzeau , Hervé Maisonneuve et al.
BMC Cancer, 2016, 16 (1), pp.802. ⟨10.1186/s12885-016-2844-6⟩
Journal articles inserm-01381110v1
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Myeloma Cell Self-Renewal Depends on JAG2 Expression and Is Mediated by IGF1 or SCF Loop

David Chiron , Sophie Maiga , Géraldine Descamps , Severine Marionneau-Lambot , Catherine Pellat-Deceunynck et al.
ASH meeting 2010, Dec 2010, Orlando, United States. pp.127, ⟨10.1182/blood.V116.21.127.127⟩
Conference papers inserm-02459063v1
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Emergence and evolution of TP53 mutations are a key feature of disease progression in myelodysplastic patients with lower-risk del(5q) treated with lenalidomide.

Laurence Lodé , Audrey Ménard , Laurent Flet , Steven Richebourg , Marion Loirat et al.
Haematologica, 2018, Epub ahead of print. ⟨10.3324/haematol.2017.181404⟩
Journal articles inserm-01691580v1
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TRAIL receptor gene editing unveils TRAIL-R1 as a master player of apoptosis induced by TRAIL and ER stress

Florent Dufour , Thibault Rattier , Andrei Alexandru Constantinescu , Luciana Zischler , Aymeric Morlé et al.
Oncotarget, 2017, 8 (6), pp.9974-9985. ⟨10.18632/oncotarget.14285⟩
Journal articles inserm-01423110v1
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A high-risk signature for patients with multiple myeloma established from the molecular classification of human myeloma cell lines.

Jérôme Moreaux , Bernard Klein , Régis Bataille , Géraldine Descamps , Sophie Maïga et al.
Haematologica, 2011, 96 (4), pp.574-82. ⟨10.3324/haematol.2010.033456⟩
Journal articles inserm-00550232v1
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BH3-mimetic toolkit guides the respective use of BCL2 and MCL1 BH3-mimetics in myeloma treatment

Patricia Gomez-Bougie , Sophie Maïga , Benoit Tessoulin , Jessie Bourcier , Antoine Bonnet et al.
Blood, 2018, Epub ahead of print. ⟨10.1182/blood-2018-03-836718⟩
Journal articles inserm-01900681v1
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The MYRACLE protocol study: a multicentric observational prospective cohort study of patients with multiple myeloma

Lina Benaniba , Benoit Tessoulin , Sabrina Trudel , Catherine Pellat-Deceunynck , Martine Amiot et al.
BMC Cancer, 2019, 19 (1), pp.855. ⟨10.1186/s12885-019-6080-8⟩
Journal articles inserm-02290127v1
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A simple flow cytometry-based barcode for routine authentication of multiple myeloma and mantle cell lymphoma cell lines

Sophie Maiga , Carole Brosseau , Géraldine Descamps , Christelle Dousset , Patricia Gomez-Bougie et al.
Cytometry Part A, 2015, 87 (4), pp.285-288. ⟨10.1002/cyto.a.22643⟩
Journal articles inserm-02100586v1

Dexamethasone-induced cell death is restricted to specific molecular subgroups of multiple myeloma

Charlotte Kervoëlen , Emmanuelle Ménoret , Patricia Gomez-Bougie , Régis Bataille , Catherine Godon et al.
Oncotarget, 2015, 6 (29), ⟨10.18632/oncotarget.4616⟩
Journal articles inserm-01817581v1
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The selectivity of Marinopyrrole A to induce apoptosis in MCL1 high BCL2 low expressing myeloma cells is related to its ability to impair protein translation

Patricia Gomez-Bougie , Christelle Dousset , Géraldine Descamps , A. Schnitzler , Logan Audiger et al.
British Journal of Haematology, 2018, ⟨10.1111/bjh.14293⟩
Journal articles inserm-01419215v1
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Rational targeted therapies to overcome microenvironment-dependent expansion of mantle cell lymphoma

David Chiron , Céline Bellanger , Antonin Papin , Benoit Tessoulin , Christelle Dousset et al.
Journal articles inserm-01405674v2
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Whole genome copy number analysis in search of new prognostic biomarkers in first line treatment of mantle cell lymphoma. A study by the LYSA group

Yannick Le Bris , Florence Magrangeas , Anne Moreau , David Chiron , Catherine Guérin-Charbonnel et al.
Hematological Oncology, 2020, Online ahead of print. ⟨10.1002/hon.2750⟩
Journal articles inserm-02874026v1
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BCL2-Family Dysregulation in B-Cell Malignancies: From Gene Expression Regulation to a Targeted Therapy Biomarker

Benoit Tessoulin , Antonin Papin , Patricia Gomez-Bougie , Céline Bellanger , Martine Amiot et al.
Frontiers in Oncology, 2019, 8, pp.645. ⟨10.3389/fonc.2018.00645⟩
Journal articles inserm-01990870v1
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The IL32/BAFF axis supports prosurvival dialogs in the lymphoma ecosystem and is disrupted by NIK inhibition

Salomé Decombis , Antonin Papin , Céline Bellanger , Clara Sortais , Christelle Dousset et al.
Haematologica, 2022, Online ahead of print. ⟨10.3324/haematol.2021.279800⟩
Journal articles inserm-03625695v1