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Molecular characterization of Netrin-1 and APP receptor binding: New leads to block the progression of senile plaques in Alzheimer's disease.
Franck Borel
,
Fanny Marzocca
,
Jean-Guy Delcros
,
Nicolas Rama
,
Patrick Mehlen
et al.
Journal articles
hal-01538747v1
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Inhibition of DNA methylation promotes breast tumor sensitivity to netrin-1 interference
M. Grandin
,
P. Mathot
,
G. Devailly
,
Y. Bidet
,
Akram Ghantous
et al.
Journal articles
hal-01792610v1
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Targeting netrin-1/DCC interaction in diffuse large B-cell and mantle cell lymphomas
Laura Broutier
,
Marion Creveaux
,
Jonathan Vial
,
Antonin Tortereau
,
Jean-Guy Delcros
et al.
Journal articles
hal-01269905v1
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Patched dependence receptor triggers apoptosis through ubiquitination of caspase-9
J. Fombonne
,
P.-A. Bissey
,
C. Guix
,
R. Sadoul
,
Chantal Thibert
et al.
Proceedings of the National Academy of Sciences of the United States of America, 2012, 109 (26), pp.10510-10515. ⟨10.1073/pnas.1200094109⟩
Journal articles
hal-03089105v1
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DCC association with lipid rafts is required for netrin-1-mediated axon guidance.
Zoltán Hérincs
,
Véronique Corset
,
Nathalie Cahuzac
,
Céline Furne
,
Valérie Castellani
et al.
Journal articles
hal-00180552v1
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Netrin-1 Interrupts Amyloid-β Amplification, Increases sAβPPα in vitro and in vivo, and Improves Cognition in a Mouse Model of Alzheimer's Disease
Patricia R. Spilman
,
Veronique Corset
,
Olivia Gorostiza
,
Karen S. Poksay
,
Veronica Galvan
et al.
Journal articles
hal-01800005v1
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The Dependence Receptor UNC5H2/B Triggers Apoptosis via PP2A-Mediated Dephosphorylation of DAP Kinase
Céline Guenebeaud
,
David Goldschneider
,
Marie Castets
,
Catherine Guix
,
Guillaume Chazot
et al.
Journal articles
hal-02664844v1
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Targeting heat shock protein 27 (HspB1) interferes with bone metastasis and tumour formation in vivo.
Benoit Gibert
,
B. Eckel
,
V. Gonin
,
D. Goldschneider
,
J. Fombonne
et al.
Journal articles
hal-00749610v1
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Sonic Hedgehog Promotes Tumor Cell Survival by Inhibiting CDON Pro-Apoptotic Activity
Céline Delloye-Bourgeois
,
Benjamin Gibert
,
Nicolas Rama
,
Jean-Guy Delcros
,
Nicolas Gadot
et al.
Journal articles
inserm-02130094v1
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Niche derived netrin-1 regulates hematopoietic stem cell dormancy via its receptor neogenin-1
Simon Renders
,
Arthur Flohr Svendsen
,
Jasper Panten
,
Nicolas Rama
,
Maria Maryanovich
et al.
Journal articles
hal-03428982v1
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NF-kappaB regulates netrin-1 expression and affects the conditional tumor suppressive activity of the netrin-1 receptors
Andrea Paradisi
,
Carine Maisse-Paradisi
,
Agnès Bernet
,
Marie-May Coissieux
,
Mauro Maccarrone
et al.
Journal articles
hal-01606730v1
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Dependence receptors: from basic research to drug development.
Patrick Mehlen
,
Dale E Bredesen
Journal articles
hal-00850822v1
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Anaplastic lymphoma kinase is a dependence receptor whose proapoptotic functions are activated by caspase cleavage.
Jaouhar Mourali
,
Alan Bénard
,
Filipe Calheiros Lourenço
,
Céline Monnet
,
Catherine Greenland
et al.
Journal articles
inserm-00111959v1
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Dependence receptor TrkC is a putative colon cancer tumor suppressor
A.-L. Genevois
,
G. Ichim
,
M.-M. Coissieux
,
M.-P. Lambert
,
F. Lavial
et al.
Proceedings of the National Academy of Sciences of the United States of America, 2013, 110 (8), pp.3017-3022. ⟨10.1073/pnas.1212333110⟩
Journal articles
hal-02360901v1
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Neurotrophins and cell death
Gabriel Ichim
,
Servane Tauszig-Delamasure
,
Patrick Mehlen
Journal articles
hal-02360903v1
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Hépatite C, EGFR, cirrhose et nétrine-1: Intérêt en hépatocarcinogenèse ?
Marie-Laure Plissonnier
,
Thomas Lahlali
,
Patrick Mehlen
,
Romain Parent
Journal articles
hal-01800027v1
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RGM and its receptor neogenin regulate neuronal survival.
E. Matsunaga
,
S. Tauszig-Delamasure
,
P.P. Monnier
,
B.K. Mueller
,
S.M. Strittmatter
et al.
Journal articles
istex
hal-00080594v1
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DCC constrains tumour progression via its dependence receptor activity.
Marie Castets
,
Laura Broutier
,
Yann Molin
,
Marie Brevet
,
Guillaume Chazot
et al.
Journal articles
istex
inserm-00721045v1
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Dependence Receptors and Cancer: Addiction to Trophic Ligands
B. Gibert
,
Patrick Mehlen
Journal articles
hal-02463298v1
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Neurotrophin-3 production promotes human neuroblastoma cell survival by inhibiting TrkC-induced apoptosis.
Jimena Bouzas-Rodriguez
,
Jorge Ruben Cabrera
,
Céline Delloye-Bourgeois
,
Gabriel Ichim
,
Jean-Guy Delcros
et al.
Journal articles
hal-00475272v1
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Inhibition of DNA methylation promotes breast tumor sensitivity to netrin‐1 interference
Mélodie Grandin
,
Pauline Mathot
,
Guillaume Devailly
,
Yannick Bidet
,
Akram Ghantous
et al.
Journal articles
hal-02956419v1
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RET modulates cell adhesion via its cleavage by caspase in sympathetic neurons.
Jorge R Cabrera
,
Jimena Bouzas-Rodriguez
,
Servane Tauszig-Delamasure
,
Patrick Mehlen
Journal articles
hal-00782733v1
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Caspase cleavage of the transcription factor FLI-1 during preB leukemic cell death.
S. Sarrazin
,
Christelle Bonod-Bidaud
,
P. Remy
,
P. Mehlen
,
F. Morle
et al.
BBA - Biochimica et Biophysica Acta, 2002, 1592, pp.123-127
Journal articles
hal-00314491v1
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Cancer-Associated Fibroblasts Produce Netrin-1 to Control Cancer Cell Plasticity
Pei-Ju Sung
,
Nicolas Rama
,
Jeromine Imbach
,
Stephany Fiore
,
Benjamin Ducarouge
et al.
Journal articles
hal-02323505v1
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Development of Targeted Microbubbles for Ultrasound Molecular Imaging of Breast Cancer
Jennifer Wischhusen
,
Jean-Guy Delcros
,
Patrick Mehlen
,
Frédéric Padilla
Journées RITS 2015, Mar 2015, Dourdan, France. pp 150-151
Conference papers
inserm-01155018v1
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Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes.
Lorenzo Galluzzi
,
Stuart A. Aaronson
,
John Abrams
,
Emad S Alnemri
,
David W. Andrews
et al.
Journal articles
inserm-00420382v1
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Caspase cleavage of the transcription factor FLI-1 during preB leukemic cell death.
S. Sarrazin
,
Christelle Bonod-Bidaud
,
P. Remy
,
P. Mehlen
,
F. Morle
et al.
Biochimica et Biophysica Acta - Molecular Cell Research, 2002, 1592 (2), pp.123-127
Journal articles
hal-00146862v1
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The Patched dependence receptor triggers apoptosis through a DRAL-caspase-9 complex.
Frédéric Mille
,
Chantal Thibert
,
Joanna Fombonne
,
Nicolas Rama
,
Catherine Guix
et al.
Journal articles
inserm-00405390v1
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Interfering with multimerization of netrin-1 receptors triggers tumor cell death.
Frédéric Mille
,
Fabien Llambi
,
Catherine Guix
,
Céline Delloye-Bourgeois
,
Céline Guenebeaud
et al.
Journal articles
inserm-00405392v1
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Immune checkpoint inhibitor treatment of a first cancer is associated with a decreased incidence of second primary cancer
P. Heudel
,
S. Chabaud
,
D. Perol
,
A. Flechon
,
J. Fayette
et al.
Journal articles
hal-03808637v1
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