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Molecular Features of the YAP Inhibitor Verteporfin: Synthesis of Hexasubstituted Dipyrrins as Potential Inhibitors of YAP/TAZ, the Downstream Effectors of the Hippo Pathway
Floriane Gibault
,
Fabrice Bailly
,
Mathieu Corvaisier
,
Mathilde Coevoet
,
Guillemette Huet
et al.
Journal articles
hal-02060557v1
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Antagonists of the adenosine A 2A receptor based on a 2-arylbenzoxazole scaffold: Investigation of the C5- and C7-positions to enhance affinity
Romain Duroux
,
Laurence Agouridas
,
Nicolas Renault
,
Jamal El Bakali
,
Christophe Furman
et al.
Journal articles
hal-02060715v1
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Synthesis and antimalarial activity of carbamate and amide derivatives of 4-anilinoquinoline
Sandrine Delarue-Cochin
,
Philippe Grellier
,
L Maes
,
Elisabeth Mouray
,
Christian Sergheraert
et al.
Journal articles
istex
mnhn-02070092v1
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Design, synthesis and antimalarial activity of a glyoxylylhydrazone library
Adina Ryckebusch
,
J-S Fruchart
,
L Cattiaux
,
P Rousselot-Paillet
,
V Leroux
et al.
Journal articles
istex
mnhn-02070128v1
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Discovery of a cryptic site at the interface 2 of TEAD – Towards a new family of YAP/TAZ-TEAD inhibitors
Manon Sturbaut
,
Fabrice Bailly
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Mathilde Coevoet
,
Pasquale Sileo
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Martine Pugniere
et al.
Journal articles
hal-03429462v1
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Identification of a New Benzimidazole Derivative as an Antiviral against Hepatitis C Virus
Thibaut Vausselin
,
Karin Séron
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Muriel Lavie
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Ahmed Atef Mesalam
,
Matthieu Lemasson
et al.
Journal articles
hal-02060744v1
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Quinazoline and phthalazine derivatives as novel melatonin receptor ligands analogues of agomelatine
Raphaël Bolteau
,
Florian Descamps
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Mohamed Ettaoussi
,
Daniel H. Caignard
,
Philippe Delagrange
et al.
Journal articles
hal-03489716v1
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A β-secretase modulator decreases Tau pathology and preserves short-term memory in a mouse model of neurofibrillary degeneration
Marie Tautou
,
Sabiha Eddarkaoui
,
Florian Descamps
,
Paul-Emmanuel Larchanché
,
Mélanie Dumoulin
et al.
2021
Preprints, Working Papers, ...
hal-03203349v1
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Synthesis and pharmacological evaluation of benzannulated derivatives as potent and selective sigma-1 protein ligands
Marion Donnier-Marechal
,
Pascal Carato
,
Delphine Le Broc
,
Christophe Furman
,
Patricia Melnyk
et al.
Journal articles
hal-02060851v1
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6-Sulfonylbenzothiazolones as potential scaffolds for the design of 5-HT6 ligands
Paul-Emmanuel Larchanche
,
Vincent Ultré
,
Delphine Le Broc
,
Céline Ballandonne
,
Christophe Furman
et al.
Journal articles
hal-01116521v1
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(Hetero)aryl substituted thiazol-2,4-yl scaffold as human carbonic anhydrase I, II, VII and XIV activators
Marouan Rami
,
Jean-Yves Winum
,
Claudiu T Supuran
,
Patricia Melnyk
,
Saïd Yous
et al.
Journal articles
hal-02060639v1
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MUC4-ErbB2 Oncogenic Complex: Binding studies using Microscale Thermophoresis
Maxime Liberelle
,
Romain Magnez
,
Xavier Thuru
,
Yamina Bencheikh
,
Séverine Ravez
et al.
Journal articles
hal-02407901v1
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Melatonergic ligands: Design, synthesis and pharmacological evaluation of novel series of naphthofuranic derivatives
Elodie Landagaray
,
Mohamed Ettaoussi
,
Romain Duroux
,
J.A. Boutin
,
Daniel-Henri Caignard
et al.
Journal articles
hal-02060776v1
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Design and synthesis of 2,6-disubstituted-8-amino imidazo[1,2a]pyridines, a promising privileged structure
Rajâa Boulahjar
,
Angela Rincon Arias
,
Raphaël Bolteau
,
Nicolas Renault
,
Mathilde Coevoet
et al.
Journal articles
hal-02060656v1
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New piperazine multi-effect drugs prevent neurofibrillary degeneration and amyloid deposition, and preserve memory in animal models of Alzheimer's disease
Nicolas Sergeant
,
Valérie Vingtdeux
,
Sabiha Eddarkaoui
,
Marion Gay
,
Caroline Evrard
et al.
Journal articles
inserm-02350071v1
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Effect of 6-Benzoyl-benzothiazol-2-one scaffold on the pharmacological profile of α-alkoxyphenylpropionic acid derived PPAR agonists
Aurélie Hurtevent
,
Morgan Le Naour
,
Veronique Leclerc
,
Pascal Carato
,
Patricia Melnyk
et al.
Journal articles
hal-02464519v2
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A Phosphosite Mutant Approach on LRRK2 Links Phosphorylation and Dephosphorylation to Protective and Deleterious Markers, Respectively
Antoine Marchand
,
Alessia Sarchione
,
Panagiotis Athanasopoulos
,
Hélène Bauderlique-Le Roy
,
Liesel Goveas
et al.
Journal articles
inserm-03625821v1
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Targeting Transcriptional Enhanced Associate Domains (TEADs)
Floriane Gibault
,
Manon Sturbaut
,
Fabrice Bailly
,
Patricia Melnyk
,
Philippe Cotelle
et al.
Journal articles
hal-02060724v1
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Synthesis and switching properties of new derivatives of azoresveratrol
Jérôme Berthet
,
Laurence Agouridas
,
Siyao Chen
,
Hassan Allouchi
,
Patricia Melnyk
et al.
Journal articles
hal-03484526v1
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La chimie en Région Hauts-de-France : Chimie, biologie et santé
Stéphane Lebrun
,
Philippe Amouyel
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Christophe Biot
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Véronique Bonnet
,
Benoît Déprez
et al.
L'Actualité Chimique, 2017, 46-51 ; http://www.lactualitechimique.org/Chimie-biologie-et-sante
Journal articles
hal-03834033v1
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Synthèse de nouveaux dérivés tétrahydroquinoléine-hydantoïne, ligands des récepteurs sigma-1
Marion Toussaint
,
Amaury Cazenave Gassiot
,
Julie Charton
,
Patricia Melnyk
20èmes Journées Franco-Belges de Pharmacochimie, 2006, Lille, France
Conference papers
hal-00101249v1
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Nouvelles molécules interagissant sur le métabolisme de l'APP
Stéphane Burlet
,
Marie Eve Grosjean
,
Vanessa Willame
,
Bénédicte Grasland
,
Antoine Ghestem
et al.
RECOB11, 2006, Aussois, France
Conference papers
hal-00101257v1
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Synthesis and antimalarial activity of new analogues of amodiaquine
Sandrine Delarue-Cochin
,
E Paunescu
,
L Maes
,
Elisabeth Mouray
,
Christian Sergheraert
et al.
Journal articles
istex
mnhn-02070095v1
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Conception, synthèse de nouveaux inhibiteurs du récepteur Met
Alexandre Barras
,
Catherine Leroy
,
Nicole Dupont
,
Dragos Horvath
,
Véronique Fafeur
et al.
Journées Jeunes Chercheurs SFC Nord, 2006, Villeneuve d'Ascq, France
Conference papers
hal-00101283v1
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Similar Structure Activity Relationships of Quinoline Derivatives for antiprion and antimalarial effects
Ralf Klingenstein
,
Patricia Melnyk
,
S. Rutger Leliveld
,
Adina Ryckebusch
,
Carsten Korth
et al.
Journal articles
istex
hal-00098660v1
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Contribution of the Endosomal-Lysosomal and Proteasomal Systems in Amyloid-β Precursor Protein Derived Fragments Processing
Caroline Evrard
,
Pascal Kieulen-Campard
,
Mathilde Coevoet
,
Rémi Opsomer
,
Bernadette Tasiaux
et al.
Journal articles
hal-02060617v1
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Non-photoinduced biological properties of Verteporfin
Floriane Gibault
,
Mathieu Corvaisier
,
Fabrice Bailly
,
Guillemette Huet
,
Patricia Melnyk
et al.
Current Medicinal Chemistry, 2016
Journal articles
hal-02060761v1
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Evaluation of three neutral capillary coatings for the determination of analyte-cyclodextrin binding constants by affinity capillary electrophoresis. Application to N,N'-disubstituted piperazine derivatives.
Cécile Danel
,
Patricia Melnyk
,
Nathalie Azaroual
,
Paul-Emmanuel Larchanché
,
Jean-Francois Goossens
et al.
Journal articles
hal-02060749v1
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A ß-Secretase Modulator Decreases Tau Pathology and Preserves Short-Term Memory in a Mouse Model of Neurofibrillary Degeneration
Marie Tautou
,
Sabiha Eddarkaoui
,
Florian Descamps
,
Paul-Emmanuel Larchanché
,
Jamal El Bakali
et al.
Journal articles
inserm-03366685v1
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Design and synthesis of fused tetrahydroisoquinoline-iminoimidazolines
Valeria Moas Heloire
,
Nicolas Renault
,
Vânia Batalha
,
Angela Rincon Arias
,
Mathieu Marchivie
et al.
Journal articles
hal-02060788v1
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