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Phenotypic Characterization of a Leishmania donovani Cyclophilin 40 Null Mutant

Wai-Lok Yau , Ulrike Lambertz , Lucie Colineau , Pascale Pescher , Andrea Macdonald , et al.
Journal of Eukaryotic Microbiology, 2016, 63 (6), pp.823-833. ⟨10.1111/jeu.12329⟩
Journal articles pasteur-01451083v1
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Dynamic imaging reveals surface exposure of virulent Leishmania amastigotes during pyroptosis of infected macrophages

Thibault Rosazza , Hervé Lecoeur , Thierry Blisnick , Maryse Moya-Nilges , Pascale Pescher , et al.
Journal of Cell Science, 2020, pp.jcs.242776. ⟨10.1242/jcs.242776⟩
Journal articles pasteur-02779320v1

Phosphoproteomic analysis of wild-type and antimony-resistant Leishmania braziliensis lines by 2D-DIGE technology

Douglas de Souza Moreira , Pascale Pescher , Christine Laurent , Pascal Lenormand , Gerald F Späth , et al.
Proteomics, 2015, 15 (17), pp.2999-3019. ⟨10.1002/pmic.201400611⟩
Journal articles istex pasteur-01433409v1

Identification of Leishmania-specific protein phosphorylation sites by LC-ESI-MS/MS and comparative genomics analyses

Sonia Hem , Pier Federico Gherardini , José Osorio y Fortéa , Veronique Hourdel , Miguel A. Morales , et al.
Proteomics, 2010, 10 (21), pp.3868-3883. ⟨10.1002/pmic.201000305⟩
Journal articles istex pasteur-01433567v1
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Post-transcriptional regulation of Leishmania fitness gain

Laura Piel , K. Shanmugha Rajan , Giovanni Bussotti , Hugo Varet , Rachel Legendre , et al.
Preprints, Working Papers, ... pasteur-03210825v1

Pharmacological assessment defines Leishmania donovani casein kinase 1 as a drug target and reveals important functions in parasite viability and intracellular infection

Najma Rachidi , Jean François Taly , Emilie Durieu , Olivier Leclercq , Nathalie Aulner , et al.
Antimicrobial Agents and Chemotherapy, 2014, 58 (3), pp.1501-1515. ⟨10.1128/AAC.02022-13⟩
Journal articles pasteur-01433412v1
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Probing druggability and biological function of essential proteins in Leishmania combining facilitated null mutant and plasmid shuffle analyses

Mariko Dacher , Miguel A Morales , Pascale Pescher , Olivier Leclercq , Najma Rachidi , et al.
Molecular Microbiology, 2014, 93, pp.146-166. ⟨10.1111/mmi.12648⟩
Journal articles hal-01178772v1

Quantitative proteome profiling informs on phenotypic traits that adapt Leishmania donovani for axenic and intracellular proliferation

Pascale Pescher , Thierry Blisnick , Philippe Bastin , Gerald F Späth
Cellular Microbiology, 2011, 13 (7), pp.978-991. ⟨10.1111/j.1462-5822.2011.01593.x⟩
Journal articles pasteur-01433560v1

Imaging host cell-Leishmania interaction dynamics implicates parasite motility, lysosome recruitment, and host cell wounding in the infection process

Claire-Lise Forestier , Christophe Machu , Celine Loussert , Pascale Pescher , Gerald F Späth
Cell Host and Microbe, 2011, 9 (4), pp.319-330. ⟨10.1016/j.chom.2011.03.011⟩
Journal articles pasteur-01433561v1
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The Leishmania donovani chaperone cyclophilin 40 is essential for intracellular infection independent of its stage-specific phosphorylation status.

Wai-Lok Yau , Pascale Pescher , Andrea Macdonald , Sonia Hem , Dorothea Zander , et al.
Molecular Microbiology, 2014, 93 (1), pp.80-97. ⟨10.1111/mmi.12639⟩
Journal articles hal-01054664v1
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Experimental evolution links post-transcriptional regulation to Leishmania fitness gain

Laura Piel , K. Shanmugha Rajan , Giovanni Bussotti , Hugo Varet , Rachel Legendre , et al.
PLoS Pathogens, 2022, 18 (3), pp.e1010375. ⟨10.1371/journal.ppat.1010375⟩
Journal articles pasteur-03615912v1
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Stage-specific expression of the proline-alanine transporter in the human pathogen Leishmania

T. Liburkin-Dan , D. Schlisselberg , R. Fischer-Weinberger , Pascale Pescher , E. Inbar , et al.
Molecular and Biochemical Parasitology, 2018, 222, pp.1-5. ⟨10.1016/j.molbiopara.2018.04.002⟩
Journal articles pasteur-01974297v1
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Comparative transcriptomic analysis of antimony resistant and susceptible Leishmania infantum lines

Juvana Moreira Andrade , Leilane Oliveira Gonçalves , Daniel Barbosa Liarte , Davi Alvarenga Lima , Frederico Gonçalves Guimarães , et al.
Parasites & Vectors, 2020, 13 (1), pp.600. ⟨10.1186/s13071-020-04486-4⟩
Journal articles pasteur-03109036v1
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Leishmania Genome Dynamics during Environmental Adaptation Reveal Strain-Specific Differences in Gene Copy Number Variation, Karyotype Instability, and Telomeric Amplification

Giovanni Bussotti , Evi Gouzelou , Mariana Côrtes Boité , Ihcen Kherachi , Zoubir Harrat , et al.
mBio, 2018, 9 (6), pp.e01399-18. ⟨10.1128/mBio.01399-18⟩
Journal articles pasteur-01974308v1
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Genome instability drives epistatic adaptation in the human pathogen Leishmania

Giovanni Bussotti , Laura Piel , Pascale Pescher , Malgorzata A. Domagalska , K. Shanmugha Rajan , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2021, 118 (51), pp.e2113744118. ⟨10.1073/pnas.2113744118⟩
Journal articles pasteur-03512631v1

A dynamic map of antigen recognition by CD4 T cells at the site of Leishmania major infection.

Orchidée Filipe-Santos , Pascale Pescher , Béatrice Breart , Christoph Lippuner , Toni Aebischer , et al.
Cell Host and Microbe, 2009, 6 (1), pp.23-33. ⟨10.1016/j.chom.2009.04.014⟩
Journal articles hal-00419292v1
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Haplotype selection as an adaptive mechanism in the protozoan pathogen Leishmania donovani

Pablo Prieto Barja , Pascale Pescher , Giovanni Bussotti , Franck Dumetz , Hideo Imamura , et al.
Nature Ecology & Evolution, 2017, 1 (12), pp.1961-1969. ⟨10.1038/s41559-017-0361-x⟩
Journal articles pasteur-02107201v1
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Alba-domain proteins of Trypanosoma brucei are cytoplasmic RNA-binding proteins that interact with the translation machinery

Jan Mani , Andreas Güttinger , Bernd Schimanski , Manfred Heller , Alvaro Acosta-Serrano , et al.
PLoS ONE, 2011, 6 (7), pp.e22463. ⟨10.1371/journal.pone.0022463⟩
Journal articles pasteur-01433563v1

Leishmania major MPK7 protein kinase activity inhibits intracellular growth of the pathogenic amastigote stage

Miguel A. Morales , Pascale Pescher , Gerald F Späth
Eukaryotic Cell, 2010, 9 (1), pp.22-30. ⟨10.1128/EC.00196-09⟩
Journal articles pasteur-01433564v1
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Reverse Epidemiology: An Experimental Framework to Drive Leishmania Biomarker Discovery in situ by Functional Genetic Screening Using Relevant Animal Models

Laura Piel , Pascale Pescher , Gerald F Späth
Frontiers in Cellular and Infection Microbiology, 2018, 8, pp.325. ⟨10.3389/fcimb.2018.00325⟩
Journal articles pasteur-01974302v1
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SILAC-based quantitative proteomics reveals pleiotropic, phenotypic modulation in primary murine macrophages infected with the protozoan pathogen Leishmania donovani

Despina Smirlis , Florent Dingli , Pascale Pescher , Eric Prina , Damarys Loew , et al.
Journal of Proteomics, 2020, 213, pp.103617. ⟨10.1016/j.jprot.2019.103617⟩
Journal articles pasteur-02750320v1