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Site-specific conjugation of auristatins onto engineered antibody fragments to target her2-positive breast cancer in vitro

Imène Ait Mohamed Amar , Nicolas Aubrey , Emilie Allard-Vannier , Juliette Lamamy , Clément Gautron et al.
32ème Colloque Biotechnocentre, Oct 2019, Seillac, France. , 85 p., 2019
Poster communications hal-02478465v1

Engineering of Neutralizing Recombinant Antibody Fragments Directed Against Venom Toxins

Philippe Billiald , Larissa M Alvarenga , Nicolas Aubrey , Matthieu Juste , Muhammad Zahid et al.
2. Oxford World Symposium on Venoms "Venoms 2013", Sep 2013, Oxford, United Kingdom. , 2013
Poster communications hal-02803725v1

Magnetic nanocarriers for the specific delivery of siRNA: Contribution of breast cancer cells active targeting for down-regulation efficiency

J. Bruniaux , E. Allard-Vannier , Nicolas Aubrey , Z. Lakhrif , S. Ben Djemaa et al.
5. Annual Meeting of the French-Society-of-Nanomedicine on Nanomedicine (SFNano) - from particule design to applications, Dec 2018, Montpellier, France
Conference papers hal-02737799v1

Design and evaluation of a diabody to improve protection against a potent scorpion neurotoxin

Nicolas Aubrey , Celine Devaux , Py Sizaret , H Rochat , M Goyffon et al.
Cellular and Molecular Life Sciences, 2003, 60 (3), pp.617-628
Journal articles hal-02671196v1

Immunodetection of the "brown" spider (Loxosceles intermedia) dermonecrotoxin with an scFv-alkaline phosphatase fusion protein

Isabella Jiacomini , Sabrina K. Silva , Nicolas Aubrey , Julien Muzard , Carlos Chávez-Olórtegui et al.
Immunology Letters, 2016, 173, pp.1-6. ⟨10.1016/j.imlet.2016.03.001⟩
Journal articles hal-02640839v1

Design of a recombinant bispecific antibody fragment for targeting Toxoplasma gondii antigen to dendritic cells

A Di Tommaso , Stephane Dion , Nicolas Aubrey , Philippe Billiald , Isabelle Dimier-Poisson et al.
Journées d’Animation Scientifique du Département Santé Animale, 2009, Port d'Albret, France. pp.Inconnu, 2009
Poster communications hal-02815932v1

An update on the use of antibodies against envenomings

Philippe Billiald , Larissa M Alvarenga , Matthieu Juste , Julien Muzard , Nicolas Aubrey et al.
18. World Congress of the International Society on Toxinology, Sep 2015, Oxford, United Kingdom
Conference papers hal-02738677v1

Engineering and functional evaluation of neutralizing antibody fragments against congenital toxoplasmosis

Anne Di Tommaso , Matthieu Juste , Zineb Lakhrif , Marie-Nöelle Mévélec , Coraline Borowczyk et al.
Journal of Infectious Diseases, 2021, 224 (4), pp.705-714. ⟨10.1093/infdis/jiab141⟩
Journal articles hal-03186466v1

Impact of Site-Specific Conjugation of ScFv to Multifunctional Nanomedicines Using Second Generation Maleimide

Katel Hervé-Aubert , Emilie Allard-Vannier , Nicolas Joubert , Zineb Lakhrif , Christophe Alric et al.
Bioconjugate Chemistry, 2018, 29 (5), pp.1553-1559. ⟨10.1021/acs.bioconjchem.8b00091⟩
Journal articles hal-01757120v1
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Multimodal nanovectors with a theranostic potential for cancer treatment

Ambre Carrouée , Christophe Alric , Stephanie David , Katel Hervé-Aubert , Nicolas Aubrey et al.
Journées RITS 2015, Mar 2015, Dourdan, France. p14-15
Conference papers inserm-01143905v1

Functional evaluation of antibody fragments against congenital toxoplasmosis

Anne Di Tommaso , Matthieu Juste , Zineb Lakhrif , Nicolas Aubrey , Guillaume Desoubeaux et al.
Immunotherapies & Innovations for Infectious Diseases-4. Congress - Digital format, Dec 2020, Digital edition, France
Conference papers hal-03186593v1

Engineering of a recombinant Fab from a neutralizing IgG directed against scorpion neurotoxin AahI, and functional evaluation versus other antibody fragments

Nicolas Aubrey , J Muzard , Jc Peter , H Rochat , M Goyffon et al.
Toxicon, 2004, 43 (3), pp.233-241
Journal articles hal-02670976v1

Targeted delivery of Toxoplasma antigens to dendritic cells to promote the immunogenicity and the protective efficiency against toxoplasmosis

Zineb Lakhrif , Isabelle Dimier-Poisson , Nathalie Moiré , Anne Di-Tommaso , A. Moreau et al.
7. édition du Club Toxo, Sep 2014, Tours, France
Conference papers hal-02792650v1
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Combination of Nanovectorized siRNA Directed against Survivin with Doxorubicin for Efficient Anti-Cancer Activity in HER2+ Breast Cancer Cells

Sahar Eljack , Emilie Allard-Vannier , Yoann Misericordia , Katel Hervé-Aubert , Nicolas Aubrey et al.
Pharmaceutics, 2022, 14 (11), pp.2537. ⟨10.3390/pharmaceutics14112537⟩
Journal articles hal-03889690v1
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Loxoscelism: Advances and Challenges in the Design of Antibody Fragments with Therapeutic Potential

Sabrina Karim-Silva , Alessandra Becker-Finco , Isabella Gizzi Jiacomini , Fanny Boursin , Arnaud Leroy et al.
Toxins, 2020, 12 (4), 22 p. ⟨10.3390/toxins12040256⟩
Journal articles mnhn-02552473v1
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Targeted Delivery of Toxoplasma gondii Antigens to Dendritic Cells Promote Immunogenicity and Protective Efficiency against Toxoplasmosis

Zineb Lakhrif , Alexis Moreau , Bruno Hérault , Anne Di-Tommaso , Matthieu Juste et al.
Frontiers in Immunology, 2018, 9, pp.1-16. ⟨10.3389/fimmu.2018.00317⟩
Journal articles hal-02627736v1
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Anticalin N- or C-Terminal on a Monoclonal Antibody Affects Both Production and In Vitro Functionality

Nicolas Aubrey , Valérie Gouilleux-Gruart , Christine Dhommée , Julie Mariot , Fanny Boursin et al.
Antibodies, 2022, 11 (3), 18 p. ⟨10.3390/antib11030054⟩
Journal articles hal-03771320v1
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Induction de sous-populations de cellules Dendritiques humaines Tolérogènes par des fragments d’anticorps

N. Kakwata-Deluce , L. Lamendour , Zineb Lakhrif , A. Nicolas , Anne Di Tommaso et al.
Journée de la Recherche Biomedicale, Dec 2017, Tours, France. , 114 p., 2017
Poster communications hal-02737129v1
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Targeted nanomedicine with anti-EGFR scFv for siRNA delivery into triple negative breast cancer cells

Phuoc Vinh Nguyen , Katel Hervé-Aubert , Stephanie David , Nolwenn Lautram , Catherine Passirani et al.
European Journal of Pharmaceutics and Biopharmaceutics, 2020, 157, pp.74-84. ⟨10.1016/j.ejpb.2020.10.004⟩
Journal articles hal-02980451v1

Antibody Fragments Humanization: Beginning with the End in Mind

Nicolas Aubrey , Philippe Billiald
Human Monoclonal Antibodies : Methods and Protocols, 1904 (2ème ed.), Humana Press, 2019, Methods in Molecular Biology, 978-1-4939-8957-7. ⟨10.1007/978-1-4939-8958-4_10⟩
Book sections hal-02789902v1
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Targeting HER2-breast tumors with scFv-decorated bimodal nanoprobes

Christophe Alric , Katel Hervé-Aubert , Nicolas Aubrey , Souad Melouk , Laurie Lajoie et al.
Journal of Nanobiotechnology, 2018, 16 (18), 13 p. ⟨10.1186/s12951-018-0341-6⟩
Journal articles hal-01808604v1

Covalent conjugation of cysteine-engineered scFv to PEGylated magnetic nanoprobes for immunotargeting of breast cancer cells

Christophe Alric , Nicolas Aubrey , Anne Di Tommaso , Thibaut Blondy , Isabelle Dimier-Poisson et al.
RSC Advances, 2016, 6 (43), pp.37099-37109. ⟨10.1039/C6RA06076E⟩
Journal articles hal-01309513v1

Site-Specific Conjugation of Auristatins onto Engineered scFv Using Second Generation Maleimide to Target HER2-positive Breast Cancer in Vitro

Nicolas Aubrey , Émilie Allard-Vannier , Camille Martin , Francesca Bryden , Stéphanie Letast et al.
Bioconjugate Chemistry, 2018, 29 (11), pp.3516-3521. ⟨10.1021/acs.bioconjchem.8b00668⟩
Journal articles hal-01907352v1

Immunogenicity and protective efficiency of antibody fragments vaccine against Toxoplasmosis in murine model

Zineb Lakhrif , Marie-Noëlle Mevelec , Anne Di-Tommaso , Matthieu Juste , Isabelle Dimier-Poisson et al.
26. Colloque Biotechnocentre, Oct 2013, Seillac, France. 2013
Poster communications hal-02808643v1

Targeted delivery of Toxoplasma antigens to dendritic cells promote immunogenicity and protective efficiency against Toxoplasmosis

Zineb Lakhrif , Marie-Noëlle Mevelec , Isabelle Dimier-Poisson , Nicolas Aubrey
28. Colloque Biotechnocentre, Oct 2015, Seillac, France. 2015
Poster communications hal-02738839v1

Immunogenicity and protective efficiency of antibody fragment vaccine against Toxoplasmosis

Zineb Lakhrif , Marie-Noëlle Mevelec , Anne Di-Tommaso , Matthieu Juste , Isabelle Dimier-Poisson et al.
PhD Day 2014, Sep 2014, Nouzilly, France
Conference papers hal-02738931v1

Screening the low molecular weight fraction of human serum using ATR-IR spectroscopy.

Franck Bonnier , Guillaume Brachet , Romain Duong , Tobiloba Sojinrin , Renaud Respaud et al.
Journal of Biophotonics, 2016, 9 (10), pp.1085-1097. ⟨10.1002/jbio.201600015⟩
Journal articles hal-01393504v1
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Engineering venom's toxin-neutralizing antibody fragments and its therapeutic potential

Larissa M Alvarenga , Muhammad Zahid , Anne Di-Tommaso , Matthieu Juste , Nicolas Aubrey et al.
Toxins, 2014, 6 (8), pp.2541-2567. ⟨10.3390/toxins6082541⟩
Journal articles hal-01123346v1

Induction de sous-populations de cellules Dendritiques humaines Tolérogènes par des fragments d'anticorps

N. Kakwata-Deluce , L. Lamendour , Zineb Lakhrif , A. Nicolas , Anne Di-Tommaso et al.
30. Colloque Biotechnocentre, Oct 2017, Seillac, France. , 100 p., 2017
Poster communications hal-02733522v1

A method to confer Protein L binding ability to any antibody fragment

Zineb Lakhrif , Martine Pugnière , Corinne Henriquet , Anne Di Tommaso , Isabelle Dimier-Poisson et al.
mAbs, 2016, 8 (2), pp.379-388. ⟨10.1080/19420862.2015.1116657⟩
Journal articles hal-02297085v1