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Phosphorylation of SAMHD1 by CyclinA2/CDK1 regulates its restriction activity towards HIV-1

A. Cribier , B. Descours , Al Chaves Valadeo , Nadine Laguette , M. Benkirane
Cell Reports, 2013, 3 (4), pp.1036-1043. ⟨10.1016/j.celrep.2013.03.017⟩
Journal articles hal-00820211v1

HIV-1 Tat assembles a multifunctional transcription elongation complex and stably associates with the 7SK snRNP.

B. Sobhian , Nadine Laguette , A. Yatim , M. Nakamura , Y. Levy , et al.
Molecular Cell, 2010, 38 (3), pp.439-451. ⟨10.1016/j.molcel.2010.04.012⟩
Journal articles hal-00485594v1

How Samhd1 changes our view of viral restriction

Nadine Laguette , Monsef Benkirane
Trends in Immunology, 2012, 33 (1), pp.26-33. ⟨10.1016/⟩
Journal articles hal-00668757v1
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Protocol to induce and assess cGAS-STING pathway activation in vitro

Hanane Chamma , Soumyabrata Guha , Nadine Laguette , Isabelle Vila
STAR Protocols, 2022, 3 (2), pp.101384. ⟨10.1016/j.xpro.2022.101384⟩
Journal articles hal-03807593v1
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DNA damage repair machinery and HIV escape from innate immune sensing

C. Brégnard , M. Benkirane , Nadine Laguette
Frontiers in Microbiology, 2014, 5, pp.176. eCollection 2014. Review. ⟨10.3389/fmicb.2014.00176⟩
Journal articles hal-01002708v1

Evolutionary and Functional Analyses of the Interaction between the Myeloid Restriction Factor SAMHD1 and the Lentiviral Vpx Protein

Nadine Laguette , N. Rahm , B. Sobhian , C. Chable-Bessia , J. Munch , et al.
Cell Host and Microbe, 2012, 11 (2), pp.205-217. ⟨10.1016/j.chom.2012.01.007⟩
Journal articles hal-00675656v1
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Sting orchestrates the crosstalk between polyunsaturated fatty acids metabolism and inflammatory responses

Isabelle Vila , Hanane Chamma , Alizée Steer , Clara Taffoni , Line Reinert , et al.
Preprints, Working Papers, ... hal-03381267v1

V1b vasopressin receptor trafficking and signaling: Role of arrestins, G proteins and Src kinase

Sanja Perkovska , Catherine Méjean , M. A. Ayoub , Juan Li , Floriane Hemery , et al.
Traffic, 2018, 19 (1), pp.58-82. ⟨10.1111/tra.12535⟩
Journal articles hal-02073197v1

Premature Activation of the SLX4 Complex by Vpr Promotes G2/M Arrest and Escape from Innate Immune Sensing

Nadine Laguette , Christelle Brégnard , Pauline Hue , J. Basbous , Ahmad Yatim , et al.
Cell, 2014, 156 (1-2), pp.134-145. ⟨10.1016/j.cell.2013.12.011⟩
Journal articles hal-00957510v1

SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates

H. Lahouassa , W. Daddacha , H. Hofmann , D. Ayinde , E. C. Logue , et al.
Nature Immunology, 2012, 13 (3), pp.223-8. doi: 10.1038/ni.2236. ⟨10.1038/ni.2236⟩
Journal articles hal-00675672v1
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Shaping of the host cell by viral accessory proteins

Nadine Laguette , M. Benkirane
Frontiers in Microbiology, 2015, 6, pp.142. ⟨10.3389/fmicb.2015.00142⟩
Journal articles hal-01131839v1
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HIV-1 Tat complexes reveal subunit composition of active P-TEFb and stable association with 7SKsnRNP

Bijan Sobhian , Nadine Laguette , Ahmad Yatim , Mirai Nakamura , Yves Levy , et al.
Journal of the International AIDS Society, 2010, 13 (Suppl 3), pp.O5. ⟨10.1186/1758-2652-13-S3-O5⟩
Journal articles inserm-00617222v1
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STING orchestrates the crosstalk between polyunsaturated fatty acid metabolism and inflammatory responses

Isabelle Vila , Hanane Chamma , Alizée Steer , Mathilde Saccas , Clara Taffoni , et al.
Cell Metabolism, 2022, 34 (1), pp.125-139.e8. ⟨10.1016/j.cmet.2021.12.007⟩
Journal articles hal-03520564v1
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Role of SAMHD1 nuclear localization in restriction of HIV-1 and SIVmac

A. Brandariz-Nuñez , J. C. Valle-Casuso , T. E. White , Nadine Laguette , M. Benkirane , et al.
Retrovirology, 2012, 9 (1), pp.49. ⟨10.1186/1742-4690-9-49⟩
Journal articles hal-00722913v1
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SAMHD1 restricts HIV-1 reverse transcription in quiescent CD4+ T-cells.

Benjamin Descours , Alexandra Cribier , Christine Chable-Bessia , Diana Ayinde , Gillian Rice , et al.
Retrovirology, 2012, 9 (1), pp.87. ⟨10.1186/1742-4690-9-87⟩
Journal articles pasteur-00750469v1
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Nucleic Acid Immunity and DNA Damage Response: New Friends and Old Foes

Clara Taffoni , Alizée Steer , Johanna Marines , Hanane Chamma , Isabelle Vila , et al.
Frontiers in Immunology, 2021, 12, pp.660560. ⟨10.3389/fimmu.2021.660560⟩
Journal articles hal-03380383v2
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Animal Models for the Study of Nucleic Acid Immunity: Novel Tools and New Perspectives

Isabelle K Vila , Maxence Fretaud , Dimitrios Vlachakis , Nadine Laguette , Christelle Langevin
Journal of Molecular Biology, 2020, 432 (20), pp.5529-5543. ⟨10.1016/j.jmb.2020.08.016⟩
Journal articles hal-02989107v1
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Lysyl-tRNA synthetase produces diadenosine tetraphosphate to curb STING-dependent inflammation

Jessica Guerra , A. L. Valadao , Dimitrios Vlachakis , K. Polak , I. K. Vila , et al.
Science Advances , 2020, 6 (21), pp.eaax3333. ⟨10.1126/sciadv.aax3333⟩
Journal articles hal-02867466v1
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Upregulated LINE-1 activity in the Fanconi Anemia cancer susceptibility syndrome leads to spontaneous pro-inflammatory cytokine production

C Brégnard , J Guerra , J Déjardin , F Passalacqua , M Benkirane , et al.
EBioMedicine, 2016, 8, pp.184-194. ⟨10.1016/j.ebiom.2016.05.005⟩
Journal articles hal-01351260v1
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Harnessing the cooperation between DNA‐PK and cGAS in cancer therapies

Clara Taffoni , Moritz Schüssler , Isabelle K Vila , Nadine Laguette
Journal articles hal-04125754v1

DNA damage repair kinase DNA‐PK and cGAS synergize to induce cancer‐related inflammation in glioblastoma

Clara Taffoni , Johanna Marines , Hanane Chamma , Soumyabrata Guha , Mathilde Saccas , et al.
EMBO Journal, 2023, 42 (7), pp.e111961. ⟨10.15252/embj.2022111961⟩
Journal articles hal-03923380v1
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Activation of STING in the pancreatic tumor microenvironment: a novel therapeutic opportunity

Hanane Chamma , Isabelle Vila , Clara Taffoni , Andrei Turtoi , Nadine Laguette
Cancer Letters, 2022, 538, pp.215694. ⟨10.1016/j.canlet.2022.215694⟩
Journal articles hal-03668657v1

SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx

Nadine Laguette , Bijan Sobhian , Nicoletta Casartelli , Mathieu Ringeard , Christine Chable-Bessia , et al.
Nature, 2011, 474 (7353), pp.654-7. ⟨10.1038/nature10117⟩
Journal articles hal-00616451v1