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Topoisomerase IIIa is required for normal proliferation and telomere stability in alternative lenghtening of telomeres.

Nassima Temine-Smaali , Lionel Guittat , Thomas Wenner , Emilie Bayart , Céline Douarre et al.
EMBO Journal, 2008, 27, pp.1513-1524. ⟨10.1038/emboj.2008.74⟩
Journal articles hal-00374479v1

Cytidine deaminase expression level in cancer as a new therapeutic target

Mounira Amor-Guéret , Hamza Mameri
Patent n° : WO2017EP57752 20170331. 2017
Patents hal-02786497v1

Cytidine deaminase deficiency reveals new therapeutic opportunities against cancer

Hamza Mameri , Ivan Bièche , Didier Meseure , Elisabetta Marangoni , Géraldine Buhagiar-Labarchède et al.
1. Course Genome Instability & Human Disease, May 2016, Orsay, France. Clinical Cancer Research, 2016
Poster communications hal-02741503v1

Pyrimidine pool imbalance induced by BLM helicase deficiency contributes to genetic instability in Bloom syndrome

Pauline Chabosseau , Géraldine Buhagiar-Labarchède , Rosine Onclercq-Delic , Sarah Lambert , Michelle Debatisse et al.
Nature Communications, 2011, 2 (1), ⟨10.1038/ncomms1363⟩
Journal articles hal-03009040v1

Cytidine deaminase deficiency impairs sister chromatid disjunction by decreasing PARP-1 activity

Simon Gemble , Géraldine Buhagiar-Labarchède , Rosine Onclercq-Delic , Christian Jaulin , Mounira Amor-Guéret et al.
Cell Cycle, 2017, 16 (11), pp.1128--1135. ⟨10.1080/15384101.2017.1317413⟩
Journal articles hal-01559255v1

Cytidine Deaminase Deficiency Reveals New Therapeutic Opportunities against Cancer

Hamza Mameri , Ivan Bieche , Didier Meseure , Elisabetta Marangoni , Géraldine Buhagiar-Labarchède et al.
Clinical Cancer Research, 2017, 23 (8), pp.2116-2126. ⟨10.1158/1078-0432.CCR-16-0626⟩
Journal articles hal-02345988v1

Identification and Analysis of Different Types of UFBs

Simon Gemble , Mounira Amor-Guéret
Homologous Recombination: Methods and Protocols, pp.187-192, 2021, ⟨10.1007/978-1-0716-0644-5_13⟩
Book sections hal-02989630v1

PARP2 controls double-strand break repair pathway choice by limiting 53BP1 accumulation at DNA damage sites and promoting end-resection

Alexis Fouquin , Josee Guirouilh-Barbat , Bernard Lopez , Janet Hall , Mounira Amor-Guéret et al.
Nucleic Acids Research, 2017, 45 (21), pp.12325-12339. ⟨10.1093/nar/gkx881⟩
Journal articles hal-03048269v1
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A decrease in NAMPT activity impairs basal PARP-1 activity in cytidine deaminase deficient-cells, independently of NAD+

Sandra Cunha Silveira , Géraldine Buhagiar-Labarchède , Rosine Onclercq-Delic , Simon Gemble , Elias Bou Samra et al.
Scientific Reports, 2020, 10 (1), ⟨10.1038/s41598-020-70874-6⟩
Journal articles hal-02918992v1

PARP2 controls double-strand break repair pathway choice by limiting 53BP1 accumulation at DNA damage sites and promoting end-resection

Alexis Fouquin , Josee Guirouilh-Barbat , Bernard Lopez , Janet Hall , Mounira Amor-Guéret et al.
Nucleic Acids Research, 2017, 45 (21), pp.12325-12339. ⟨10.1093/nar/gkx881⟩
Journal articles hal-02345983v1
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Cytidine deaminase deficiency in tumor cells is associated with sensitivity to a naphthol derivative and a decrease in oncometabolite levels

Hamza Mameri , Géraldine Buhagiar-Labarchède , Gaëlle Fontaine , Céline Corcelle , Caroline Barette et al.
Cellular and Molecular Life Sciences, 2022, 79 (8), pp.465. ⟨10.1007/s00018-022-04487-9⟩
Journal articles hal-03766208v1

DNA damage: RNA-binding proteins protect from near and far

Martin Dutertre , Sarah Lambert , Aura Carreira , Mounira Amor-Guéret , Stéphan Vagner et al.
Trends in Biochemical Sciences, 2014, 39 (3), pp.141-149. ⟨10.1016/j.tibs.2014.01.003⟩
Journal articles hal-03008987v1
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Pyrimidine Pool Disequilibrium Induced by a Cytidine Deaminase Deficiency Inhibits PARP-1 Activity, Leading to the Under Replication of DNA

Simon Gemble , Akshay Ahuja , Géraldine Buhagiar-Labarchède , Rosine Onclercq-Delic , Julien Dairou et al.
PLoS Genetics, 2015, 11 (7), pp.e1005384. ⟨10.1371/journal.pgen.1005384⟩
Journal articles hal-02345993v1
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A role for Tau protein in maintaining ribosomal DNA stability and cytidine deaminase-deficient cell survival

Elias Bou Samra , Géraldine Buhagiar-Labarchède , Christelle Machon , Jérôme Guitton , Rosine Onclercq-Delic et al.
Nature Communications, 2017, 8 (1), ⟨10.1038/s41467-017-00633-1⟩
Journal articles hal-02345938v1
Image document

Bloom syndrome protein restrains innate immune sensing of micronuclei by cGAS

Matthieu Gratia , Mathieu Rodéro , Cécile Conrad , Elias Bou Samra , Mathieu L Maurin et al.
Journal of Experimental Medicine, 2019, 216 (5), pp.jem.20181329. ⟨10.1084/jem.20181329⟩
Journal articles pasteur-02119258v1
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Topoisomerase IIα prevents ultrafine anaphase bridges by two mechanisms

Simon Gemble , Géraldine Buhagiar-Labarchède , Rosine Onclercq-Delic , Gaëlle Fontaine , Sarah Lambert et al.
Open Biology, 2020, 10 (5), pp.190259. ⟨10.1098/rsob.190259⟩
Journal articles hal-02989648v1
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A balanced pyrimidine pool is required for optimal Chk1 activation to prevent ultrafine anaphase bridge formation

Simon Gemble , Géraldine Buhagiar-Labarchède , Rosine Onclercq-Delic , Denis Biard , Sarah Lambert et al.
Journal of Cell Science, 2016, 129 (16), pp.3167-3177. ⟨10.1242/jcs.187781⟩
Journal articles hal-02345992v1
Image document

Bloom's Syndrome and PICH Helicases Cooperate with Topoisomerase IIα in Centromere Disjunction before Anaphase.

Sébastien Rouzeau , Fabrice P. Cordelières , Géraldine Buhagiar-Labarchède , Ilse Hurbain , Rosine Onclercq-Delic et al.
PLoS ONE, 2012, 7 (4), pp.e33905. ⟨10.1371/journal.pone.0033905⟩
Journal articles inserm-00696960v1

Cytidine deaminase: is it a marker of sensitivity/reistance to antitumor drugs?

Hamza Mameri , Géraldine Buhagiar-Labarchère , Rosine Onclercq-Delic , Mounira Amor-Guéret
1. Joint Symposium Curie-Gray institutes, Apr 2014, Oxford, United Kingdom. 2014
Poster communications hal-02738887v1

The Bloom Syndrome Protein Limits the Lethality Associated with RAD51 Deficiency

Kenza Lahkim Bennani-Belhaj , Sébastien Rouzeau , Géraldine Buhagiar-Labarchède , Pauline Chabosseau , Rosine Onclercq-Delic et al.
Molecular Cancer Research, 2010, 8 (3), pp.385-394. ⟨10.1158/1541-7786.MCR-09-0534⟩
Journal articles hal-02346011v1

A Major Role for Mitotic cdc2 Kinase Inactivation in the Establishment of the Mitotic DNA Damage Checkpoint

Emilie Bayart , Olga Grigorieva , Serge Leibovitch , Rosine Onclercq-Delic , Mounira Amor-Guéret et al.
Cancer Research, 2004, 64 (24), pp.8954-8959. ⟨10.1158/0008-5472.CAN-04-1613⟩
Journal articles hal-02346035v1