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Polyheteroaryl Oxazole/Pyridine-Based Compounds Selected in Vitro as G-Quadruplex Ligands Inhibit Rock Kinase and Exhibit Antiproliferative Activity

Daniela Verga , Chi-Hung N'Guyen , Daniela Verga , Chi-Hung N'Guyen , Malika Dakir et al.
Journal of Medicinal Chemistry, 2018, ⟨10.1021/acs.jmedchem.8b01023⟩
Journal articles hal-02392101v1
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Nucleolin directly mediates Epstein-Barr virus immune evasion through binding to G-quadruplexes of EBNA1 mRNA

María José Lista , Rodrigo Prado Martins , Olivier Billant , Marie-Astrid Contesse , Sarah Findakly et al.
Nature Communications, 2017, 8 (1), pp.14 - 27. ⟨10.1038/ncomms16043⟩
Journal articles hal-01682747v1
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Linking of Antitumor trans NHC-Pt(II) Complexes to G-Quadruplex DNA Ligand for Telomeric Targeting

Jean-François Betzer , Frédérick Nuter , Mélanie Chtchigrovsky , Florian Hamon , Guillaume Kellermann et al.
Bioconjugate Chemistry, 2016, 27 (6), pp.1456-1470. ⟨10.1021/acs.bioconjchem.6b00079⟩
Journal articles hal-02152296v1

Selective recognition of pyrimidine-pyrimidine DNA mismatches by distance-constrained macrocyclic bis-intercalators

M. Bahr , V. Gabelica , A. Granzhan , Marie-Paule Teulade-Fichou , E. Weinhold et al.
Nucleic Acids Research, 2008, 36 (15), pp.5000-5012
Journal articles hal-00321538v1

Plasmodium telomeric sequences: structure, stability and quadruplex targeting by small compounds

A. de Cian , P. Grellier , E. Mouray , D. Depoix , Hélène Bertrand et al.
ChemBioChem, 2008, 9, pp.2730
Journal articles hal-00339356v1

Double threading through DNA: NMR structural study of a bis-naphthalene macrocycle bound to a thymine–thymine mismatch

Muriel Jourdan , Anton Granzhan , Régis Guillot , Pascal Dumy , Marie-Paule Teulade-Fichou et al.
Nucleic Acids Research, 2012, 40 (11), pp.5115 - 5128. ⟨10.1093/nar/gks067⟩
Journal articles hal-01654807v1
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Ligand-Induced Conformational Changes with Cation Ejection upon Binding to Human Telomeric DNA G-Quadruplexes

Adrien Marchand , Anton Granzhan , Keisuke Iida , Yamato Tsushima , Yue Ma et al.
Journal of the American Chemical Society, 2015, 137 (2), pp.750-756. ⟨10.1021/ja5099403⟩
Journal articles hal-01524156v1
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Novel hydrazone derivatives for preventing or treating EBV-related cancers

Rodrigo Prado Martins , R Fahraeus , C Daskalogianni , Marie-Paule Teulade-Fichou , A Granzhan et al.
Patent n° : 18305392.5 – 1110. 2018
Patents hal-02786500v1

Stabilization and structure of telomeric and c-myc region intramolecular G-quadruplexes: the role of central cations and small planar ligands.

Valérie Gabelica , Erin S. Baker , Marie-Paule Teulade-Fichou , Edwin de Pauw , Michael T. Bowers et al.
Journal of the American Chemical Society, 2007, 129 (4), pp.895-904. ⟨10.1021/ja065989p⟩
Journal articles istex hal-00258139v1

Locking the free-rotation of a prochiral star-shaped guest molecule inside a two-dimensional nanoporous network by introduction of chlorine atoms.

Hélène Bertrand , Fabien Silly , Marie-Paule Teulade-Fichou , Ludovic Tortech , Denis Fichou et al.
Chemical Communications, 2011, 47 ((36)), pp.10091-3. ⟨10.1039/c1cc12951a⟩
Journal articles hal-00663141v1
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Platinum Complexes Can Bind to Telomeres by Coordination

Lina Saker , Samar Ali , Caroline Masserot , Guillaume Kellermann , Joël Poupon et al.
International Journal of Molecular Sciences, 2018, ⟨10.3390/ijms19071951⟩
Journal articles hal-02390319v1

DNA Switches on the Two-Photon Efficiency of an Ultrabright Triphenylamine Fluorescent Probe Specific of AT Regions

Blaise Dumat , Guillaume Bordeau , Elodie Faurel-Paul , Florence Mahuteau-Betzer , Nicolas Saettel et al.
Journal of the American Chemical Society, 2013, 135 (34), pp.12697 - 12706. ⟨10.1021/ja404422z⟩
Journal articles cea-01478825v1

“ One Ring to Bind Them All ”—Part I: The Efficiency of the Macrocyclic Scaffold for G-Quadruplex DNA Recognition

Anton Granzhan , David Monchaud , Nicolas Saettel , Aurore Guédin , Jean-Louis Mergny et al.
Journal of Nucleic Acids , 2010, 2010, pp.1-19. ⟨10.4061/2010/525862⟩
Journal articles hal-02125702v1
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“ One Ring to Bind Them All ”—Part I: The Efficiency of the Macrocyclic Scaffold for G-Quadruplex DNA Recognition

David Monchaud , Anton Granzhan , Nicolas Saettel , Aurore Guédin , Jean-Louis Mergny et al.
Journal of Nucleic Acids , 2010, 2010, pp.1-19. ⟨10.4061/2010/525862⟩
Journal articles hal-02125700v1

Synthesis, properties, and remarkable 2 D Self-Assembly at the Liquid/Solid interface of a series of triskele-shaped 5,11,17-triazatrinaphthylenes (TrisK).

Hélène Bertrand , Régis Guillot , Marie-Paule Teulade-Fichou , Denis Fichou
Chemistry - A European Journal, 2013, 19 ((43)), pp.14654-64. ⟨10.1002/chem.201300705⟩
Journal articles istex hal-01073591v1
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Topology-Selective Fluorescent "Light-Up" Probes for G-Quadruplex DNA Based on Photoinduced Electron Transfer

Xiao Xie , Oksana Reznichenko , Ludovic Chaput , Pascal G.P. Martin , Marie-Paule Teulade-Fichou et al.
Chemistry - A European Journal, 2018, ⟨10.1002/chem.201801701⟩
Journal articles hal-01821778v1

Development of a fluorescent intercalator displacement assay (G4-FID) for establishing quadruplex-DNA affinity and selectivity of putative ligands

David Monchaud , Clémence Allain , Marie-Paule Teulade-Fichou
Bioorganic and Medicinal Chemistry Letters, 2006, 16 (18), pp.4842-4845. ⟨10.1016/j.bmcl.2006.06.067⟩
Journal articles istex hal-02124555v1

A hitchhiker's guide to G-quadruplex ligands

David Monchaud , Marie-Paule Teulade-Fichou
Organic & Biomolecular Chemistry, 2008, 6 (4), pp.627-636. ⟨10.1039/B714772B⟩
Journal articles istex hal-02125642v1

Exclusive platination of loop adenines in the human telomeric G-quadruplex

Hélène Bertrand , Sophie Bombard , David Monchaud , Eric Talbot , Aurore Guédin et al.
Organic & Biomolecular Chemistry, 2009, 7 (14), pp.2864. ⟨10.1039/B904599F⟩
Journal articles istex hal-02125660v1

Vinyl-diazine triphenylamines and their N-methylated derivatives: synthesis, photophysical properties and application for staining DNA

Ana Aranda , Sylvain Achelle , Fabien Hammerer , Florence Mahuteau-Betzer , Marie-Paule Teulade-Fichou et al.
Dyes and Pigments, 2012, 95 (2), pp.400-407. ⟨10.1016/j.dyepig.2012.04.009⟩
Journal articles hal-00863086v1

Carbohydrate-conjugated porphyrin dimers: synthesis and photobiological evaluation for a potential application in one-photon and two-photon photodynamic therapy.

Guillaume Garcia , Fabien Hammerer , Florent Poyer , Sylvain Achelle , Marie-Paule Teulade-Fichou et al.
Bioorganic and Medicinal Chemistry, 2013, 21 (1), pp.153-65. ⟨10.1016/j.bmc.2012.10.042⟩
Journal articles hal-00878575v1

Design and synthesis of Epicocconone-DNA binder hybrids : Analysing the DNA-Protein interaction

Stéphane Leleu , Xavier Franck , Romain Mougeot , Florence Mahuteau-Betzer , Marie-Paule Teulade-Fichou et al.
French-Japanese Symposium of Medicinal and Fine Chemistry (26, 2017), Sep 2017, Strasbourg, France
Poster communications hal-02370800v1

Rudimentary G-quadruplex–based telomere capping in Saccharomyces cerevisiae

Jasmine Smith , Qijun Chen , Liliya Yatsunyk , John Nicoludis , Mark Garcia et al.
Nature Structural and Molecular Biology, 2011, 18 (4), pp.478-485. ⟨10.1038/nsmb.2033⟩
Journal articles hal-02125707v1
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Modulation of cellular fate of vinyl triarylamines through structural fine tuning: to stay or not to stay in the mitochondria?

Laura Fourmois , Florent Poyer , Aude Sourdon , Delphine Naud-Martin , Sounderya Nagarajan et al.
ChemBioChem, 2021, 22 (14), pp.2457-2467. ⟨10.1002/cbic.202100168⟩
Journal articles hal-03333512v1

A platinum-quinacridine hybrid as a G-quadruplex ligand.

Hélène Bertrand , Sophie Bombard , David Monchaud , Marie-Paule Teulade-Fichou
Journal of Biological Inorganic Chemistry, 2007, 12 (7), pp.1003-14. ⟨10.1007/s00775-007-0273-3⟩
Journal articles istex hal-00259082v1
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Identification of optimal fluorescent probes for G-quadruplex nucleic acids through systematic exploration of mono- and distyryl dye libraries

Xiao Xie , Michela Zuffo , Marie-Paule Teulade-Fichou , Anton Granzhan
Beilstein Journal of Organic Chemistry, 2019, 15, pp.1872-1889. ⟨10.3762/bjoc.15.183⟩
Journal articles hal-02344509v1

Influence of carbohydrate biological vectors on the two-photon resonance of porphyrin oligomers.

Fabien Hammerer , Sylvain Achelle , Patrice L. Baldeck , Philippe Maillard , Marie-Paule Teulade-Fichou et al.
Journal of Physical Chemistry A, 2011, 115 (24), pp.6503-8. ⟨10.1021/jp202436x⟩
Journal articles hal-00875509v1

Un conjugué Quinacridine-Platine en tant que ligand d'ADN G-quadruplexe

Hélène Bertrand, , Sophie Bombard , David Monchaud, , Marie-Paule Teulade-Fichou,
Un conjugué Quinacridine-Platine en tant que ligand d'ADN G-quadruplexe, Feb 2008, Albé,, France
Conference papers hal-00787044v1

Influence of Carbohydrate Biological Vectors on the Two-Photon Resonance of Porphyrin Oligomers

Fabien Hammerer , S. Achelle , Patrice L. Baldeck , Philippe Maillard , Marie-Paule Teulade-Fichou et al.
Journal of Physical Chemistry A, 2011, 115, pp.6503-6508
Journal articles hal-00603243v1
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Highly efficient radiosensitization of human glioblastoma and lung cancer cells by a G-quadruplex DNA binding compound

Patrick Merle , Marine Gueugneau , Marie-Paule Teulade-Fichou , Mélanie Müller-Barthélémy , Simon Amiard et al.
Scientific Reports, 2015, 5 (1), ⟨10.1038/srep16255⟩
Journal articles inserm-01907350v1