Search - Archive ouverte HAL Access content directly

Filter your results

47 Results

A new type of scorpion Na+-channel-toxin-like polypeptide active on K+ channels.

Najet Srairi-Abid , Joseba Inaki Guijarro , Rym Benkhalifa , Massimo Mantegazza , Amani Cheikh et al.
Biochemical Journal, 2005, 388, pp.455-464. ⟨10.1042/BJ20041407⟩
Journal articles hal-00018752v1

Depletion of the Fragile X Mental Retardation Protein in Embryonic Stem Cells Alters the Kinetics of Neurogenesis

Sandrine Cestèle , Olfa Khalfallah , Marielle Jarjat , Laetitia Davidovic , Nicolas Nottet et al.
STEM CELLS, 2017, 35 (2), pp.374-385. ⟨10.1002/stem.2505⟩
Journal articles hal-02352053v1

Rescuable folding defective NaV1.1 (SCN1A) mutants in epilepsy: Properties, occurrence, and novel rescuing strategy with peptides targeted to the endoplasmic reticulum

Sandrine Cestèle , Giulia Bechi , Raffaella Rusconi , Sandrine Cestele , Pasquale Striano et al.
Neurobiology of Disease, 2015, 75, pp.100-114. ⟨10.1016/j.nbd.2014.12.028⟩
Journal articles hal-02352057v1
Image document

Gain of Function for the SCN1A/hNav1.1-L1670W Mutation Responsible for Familial Hemiplegic Migraine

Sandra Dhifallah , Eric Lancaster , Shana Merrill , Nathalie Leroudier , Massimo Mantegazza et al.
Frontiers in Molecular Neuroscience, 2018, 11, pp.232. ⟨10.3389/fnmol.2018.00232⟩
Journal articles hal-02352023v1

iPSC-derived neurons of CREBBP - and EP300 -mutated Rubinstein-Taybi syndrome patients show morphological alterations and hypoexcitability

Valentina Alari , Silvia Russo , Benedetta Terragni , Paola Francesca Ajmone , Alessandra Sironi et al.
Stem Cell Research, 2018, 30, pp.130-140. ⟨10.1016/j.scr.2018.05.019⟩
Journal articles hal-02562805v1

The gain of function SCN1A disorder spectrum: novel epilepsy phenotypes and therapeutic implications

Andreas Brunklaus , Tobias Brünger , Tony Feng , Carmen Fons , Anni Lehikoinen et al.
Brain - A Journal of Neurology , 2022, ⟨10.1093/brain/awac210⟩
Journal articles hal-03753793v1
Image document

Cholinergic modulation inhibits cortical spreading depression in mouse neocortex through activation of muscarinic receptors and decreased excitatory/inhibitory drive

Sarah Zerimech , Oana Chever , Paolo Scalmani , Lara Pizzamiglio , Fabrice Duprat et al.
Neuropharmacology, 2020, 166, pp.107951. ⟨10.1016/j.neuropharm.2020.107951⟩
Journal articles hal-02454613v1

Divergent effects of the T1174S SCN1A mutation associated with seizures and hemiplegic migraine.

Sandrine Cestèle , Angelo Labate , Raffaella Rusconi , Patrizia Tarantino , Laura Mumoli et al.
Epilepsia, 2013, 54 (5), pp.927-35. ⟨10.1111/epi.12123⟩
Journal articles hal-00854584v1

Hippocampal hyperexcitability and specific epileptiform activity in a mouse model of Dravet syndrome.

Camille Liautard , Paolo Scalmani , Giovanni Carriero , Marco de Curtis , Silvana Franceschetti et al.
Epilepsia, 2013, 54 (7), pp.1251-61. ⟨10.1111/epi.12213⟩
Journal articles hal-00854574v1

Voltage-gated sodium channels as therapeutic targets in epilepsy and other neurological disorders.

Massimo Mantegazza , Giulia Curia , Giuseppe Biagini , David S Ragsdale , Massimo Avoli et al.
The Lancet Neurology, 2010, 9 (4), pp.413-24. ⟨10.1016/S1474-4422(10)70059-4⟩
Journal articles hal-00497216v1
Image document

Developmental and epileptic encephalopathies: from genetic heterogeneity to phenotypic continuum

Renzo Guerrini , Valerio Conti , Massimo Mantegazza , Simona Balestrini , Aristea S Galanopoulou et al.
Physiological Reviews, In press, ⟨10.1152/physrev.00063.2021⟩
Journal articles hal-03759582v1
Image document

Initiation of migraine-related cortical spreading depolarization by hyperactivity of GABAergic neurons and NaV1.1 channels

Oana Chever , Sarah Zerimech , Paolo Scalmani , Louisiane Lemaire , Lara Pizzamiglio et al.
The Journal of clinical investigation, 2021, 131 (21), pp.e142203. ⟨10.1172/JCI142203⟩
Journal articles hal-03411366v1
Image document

Modeling cortical spreading depression induced by the hyperactivity of interneurons

Mathieu Desroches , Olivier Faugeras , Martin Krupa , Massimo Mantegazza
Journal of Computational Neuroscience, 2019, ⟨10.1007/s10827-019-00730-8⟩
Journal articles hal-01520200v1

Epilepsy: Advances in genetics and pathophysiology

Massimo Mantegazza
Neuroscience Letters, 2018, 667, pp.1-3. ⟨10.1016/j.neulet.2017.10.026⟩
Journal articles hal-02562807v1
Image document

SULT4A1 Modulates Synaptic Development and Function by Promoting the Formation of PSD-95/NMDAR Complex

Lorenza Culotta , Paolo Scalmani , Ersilia Vinci , Benedetta Terragni , Alessandro Sessa et al.
Journal of Neuroscience, 2020, 40 (37), pp.7013-7026. ⟨10.1523/JNEUROSCI.2194-19.2020⟩
Journal articles hal-03011735v1
Image document

Modeling NaV1.1/SCN1A sodium channel mutations in a microcircuit with realistic ion concentration dynamics suggests differential GABAergic mechanisms leading to hyperexcitability in epilepsy and hemiplegic migraine

Louisiane Lemaire , Mathieu Desroches , Martin Krupa , Lara Pizzamiglio , Paolo Scalmani et al.
PLoS Computational Biology, 2021, 17 (7), pp.e1009239. ⟨10.1371/journal.pcbi.1009239⟩
Journal articles hal-03191275v2

DNA damage and transcriptional regulation in iPSC-derived neurons from Ataxia Telangiectasia patients

Alessandro Corti , Raina Sota , Matteo Dugo , Raffaele Calogero , Benedetta Terragni et al.
Scientific Reports, 2019, 9 (1), pp.1-13. ⟨10.1038/s41598-018-36912-0⟩
Journal articles hal-02560558v1

First chemical synthesis of a scorpion α-toxin affecting sodium channels: The Aah I toxin of Androctonus australis hector

Sarrah M'Barek , Ziad Fajloun , Sandrine Cestèle , Christiane Devaux , Pascal Mansuelle et al.
Journal of Peptide Science, 2004, 10 (11), pp.666-677. ⟨10.1002/psc.582⟩
Journal articles istex pasteur-02052144v1

Epileptogenic ion channel mutations: from bedside to bench and, hopefully, back again.

Massimo Mantegazza , Raffaella Rusconi , Paolo Scalmani , Giuliano Avanzini , Silvana Franceschetti et al.
Epilepsy Research, 2010, 92 (1), pp.1-29. ⟨10.1016/j.eplepsyres.2010.08.003⟩
Journal articles hal-00854529v1

Network topology of NaV1.7 mutations in sodium channel-related painful disorders

Sandrine Cestèle , Benedetta Terragni , Paolo Scalmani , Silvana Franceschetti , Massimo Mantegazza et al.
BMC Systems Biology, 2017, 11 (1), pp.28. ⟨10.1186/s12918-016-0382-0⟩
Journal articles hal-03572479v1

A two-hit story: Seizures and genetic mutation interaction sets phenotype severity in SCN1A epilepsies

Ana Rita Salgueiro-Pereira , Fabrice Duprat , Paula Pousinha , Alexandre Loucif , Vincent Douchamps et al.
Neurobiology of Disease, 2019, 125, pp.31-44. ⟨10.1016/j.nbd.2019.01.006⟩
Journal articles hal-02166065v1
Image document

A companion to the preclinical common data elements for rodent models of pediatric acquired epilepsy: A report of the TASK3‐WG1B, Pediatric and Genetic Models Working Group of the ILAE-AES Joint Translational Task Force

Anna‐maria Katsarou , Hana Kubova , Stéphane Auvin , Massimo Mantegazza , Melissa Barker‐haliski et al.
Epilepsia Open, In press, ⟨10.1002/epi4.12641⟩
Journal articles hal-03761735v1

Rare coding variants in genes encoding GABAA receptors in genetic generalised epilepsies: an exome-based case-control study

Sandrine Cestèle , Peter De Jonghe , M Arfan Ikram , Patrick May , Simon Girard et al.
The Lancet Neurology, 2018, 17 (8), pp.699-708. ⟨10.1016/S1474-4422(18)30215-1⟩
Journal articles hal-02352036v1

Loss-of-function KCNH2 mutation in a family with long QT syndrome, epilepsy, and sudden death.

Sara Partemi , Sandrine Cestèle , Marianna Pezzella , Oscar Campuzano , Roberta Paravidino et al.
Epilepsia, 2013, 54 (8), pp.e112-6. ⟨10.1111/epi.12259⟩
Journal articles hal-00854562v1

The 22nd Ion Channel Meeting, September 2011, France

Jean-Marc Goaillard , Laurent Groc , Sabine Lévi , Massimo Mantegazza , Fabrice Matifat et al.
Channels, 2014, 6 (3), pp.149-153. ⟨10.4161/chan.20795⟩
Journal articles hal-02277638v1

The impact of genetic and experimental studies on classification and therapy of the epilepsies

Sandrine Cestèle , Giuliano Avanzini , Massimo Mantegazza , Benedetta Terragni , Laura Canafoglia et al.
Neuroscience Letters, 2018, 667, pp.17-26. ⟨10.1016/j.neulet.2017.05.026⟩
Journal articles hal-02562808v1

Hyperexcitability in Cultured Cortical Neuron Networks from the G93A-SOD1 Amyotrophic Lateral Sclerosis Model Mouse and its Molecular Correlates

Stefania Marcuzzo , Benedetta Terragni , Silvia Bonanno , Davide Isaia , Paola Cavalcante et al.
Neuroscience, 2019, 416, pp.88-99. ⟨10.1016/j.neuroscience.2019.07.041⟩
Journal articles hal-02560551v1
Image document

Beta-scorpion toxin effects suggest electrostatic interactions in domain II of voltage-dependent sodium channels.

Massimo Mantegazza , Sandrine Cestèle
The Journal of Physiology, 2005, 568 (Pt 1), pp.13-30. ⟨10.1113/jphysiol.2005.093484⟩
Journal articles inserm-00381745v1
Image document

Fluorescent‐ and tagged‐protoxin II peptides: potent markers of the Na v 1.7 channel pain target

Jérôme Montnach , Stephan de Waard , Sébastien Nicolas , Sophie Burel , Nancy Osorio et al.
British Journal of Pharmacology, 2021, 178 (13), pp.2632-2650. ⟨10.1111/bph.15453⟩
Journal articles hal-03367780v1
Image document

Sodium channelopathies of skeletal muscle and brain

Sandrine Cestèle , Massimo Mantegazza , William Catterall
Physiological Reviews, 2021, 101 (4), pp.1633-1689. ⟨10.1152/physrev.00025.2020⟩
Journal articles hal-03411361v1