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IN VIVO LARGE SCALE MAPPING OF PROTEIN TURNOVER IN THE HUMAN CEREBROSPINAL FLUID

Sylvain Lehmann , Christophe Hirtz , Jérôme Vialaret , Maxence Ory , Guillaume Gras Combes et al.
Analytical Chemistry, 2019, 91 (24), pp.15500-15508. ⟨10.1021/acs.analchem.9b03328⟩
Journal articles hal-02368099v1

Germline RBBP6 mutations in familial myeloproliferative neoplasms

Ashot Harutyunyan , Roberto Giambruno , Christian Krendl , Alexey Stukalov , Thorsten Klampfl et al.
Blood, 2016, 127 (3), pp.362-365. ⟨10.1182/blood-2015-09-668673⟩
Journal articles hal-02296271v1

NOTCH1 activation in breast cancer confers sensitivity to inhibition of SUMOylation

M Licciardello , M Müllner , G Dürnberger , C Kerzendorfer , B Boidol et al.
Oncogene, 2015, 34 (29), pp.3780-3790. ⟨10.1038/onc.2014.319⟩
Journal articles hal-02287227v1

Proteome-wide drug and metabolite interaction mapping by thermal-stability profiling

Kilian Huber , Karin Olek , André Müller , Chris Soon Heng Tan , Keiryn Bennett et al.
Nature Methods, 2015, 12 (11), pp.1055-1057. ⟨10.1038/nmeth.3590⟩
Journal articles hal-02329771v1

Gene essentiality and synthetic lethality in haploid human cells

V. Blomen , P. Majek , L. Jae , J. Bigenzahn , J. Nieuwenhuis et al.
Science, 2015, 350 (6264), pp.1092-1096. ⟨10.1126/science.aac7557⟩
Journal articles hal-02337430v1

Superoxide Dismutase 1 Protects Hepatocytes from Type I Interferon-Driven Oxidative Damage

Anannya Bhattacharya , Ahmed n. Hegazy , Nikolaus Deigendesch , Lindsay Kosack , Jovana Cupovic et al.
Immunity, 2015, 43 (5), pp.974-986. ⟨10.1016/j.immuni.2015.10.013⟩
Journal articles hal-02336008v1

Early-onset inflammatory bowel disease and common variable immunodeficiency-like disease caused by IL-21 deficiency

E. Salzer , A. Kansu , H. Sic , P. Majek , A. Ikinciogullari et al.
Journal of Allergy and Clinical Immunology, 2014, 133, pp.1651--9 e12. ⟨10.1016/j.jaci.2014.02.034⟩
Journal articles hal-02168078v1

MAGI1 inhibits the AMOTL2/p38 stress pathway and prevents luminal breast tumorigenesis

Diala Kantar , Emilie Bousquet Mur , Vera Slaninova , Yezza Ben Salah , Luca Costa et al.
2020
Preprints, Working Papers, ... hal-03066045v1

A Surface Biotinylation Strategy for Reproducible Plasma Membrane Protein Purification and Tracking of Genetic and Drug-Induced Alterations

Katrin Hörmann , Alexey Stukalov , André Müller , Leonhard Heinz , Giulio Superti-Furga et al.
Journal of Proteome Research, 2016, 15 (2), pp.647-658. ⟨10.1021/acs.jproteome.5b01066⟩
Journal articles hal-02296681v1

A combinatorial screen of the CLOUD uncovers a synergy targeting the androgen receptor

Marco Licciardello , Anna Ringler , Patrick Markt , Freya Klepsch , Charles-Hugues Lardeau et al.
Nature Chemical Biology, 2017, 13 (7), pp.771-778. ⟨10.1038/nchembio.2382⟩
Journal articles hal-02278677v1
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Mechanisms underlying the cooperation between loss of epithelial polarity and Notch signaling during neoplastic growth in Drosophila

Rémi Logeay , Charles Géminard , Patrice Lassus , Miriam Rodríguez-Vázquez , Diala Kantar et al.
Development (Cambridge, England), 2022, 149 (3), pp.dev200110. ⟨10.1242/dev.200110⟩
Journal articles hal-03738484v1
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The Prognostic Impact of the Aryl Hydrocarbon Receptor (AhR) in Primary Breast Cancer Depends on the Lymph Node Status

Udo Jeschke , Xi Zhang , Christina Kuhn , Stéphan Jalaguier , Jacques Colinge et al.
International Journal of Molecular Sciences, 2019, 20 (5), pp.1016. ⟨10.3390/ijms20051016⟩
Journal articles inserm-02414817v2

Identification of kinase inhibitor targets in the lung cancer microenvironment by chemical and phosphoproteomics

M. Gridling , S. B. Ficarro , F. P. Breitwieser , L. Song , K. Parapatics et al.
Molecular Cancer Therapeutics, 2014, 13, pp.2751--62. ⟨10.1158/1535-7163.MCT-14-0152⟩
Journal articles hal-02168074v1

Définition et applications cliniques des radiomics

C. Bourgier , Jacques Colinge , N. Aillères , P. Fenoglietto , M. Brengues et al.
Cancer/Radiothérapie, 2015, 19 (6-7), pp.532-537. ⟨10.1016/j.canrad.2015.06.008⟩
Journal articles hal-02318081v1
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Machine Learning‐Assisted Evaluation of Circulating DNA Quantitative Analysis for Cancer Screening

Rita Tanos , Guillaume Tosato , Amaelle Otandault , Zahra Al Amir Dache , Laurence Pique Lasorsa et al.
Advanced Science, 2020, 7 (18), pp.2000486. ⟨10.1002/advs.202000486⟩
Journal articles hal-03337999v1

Comprehensive comparative and semiquantitative proteome of a very low number of native and matched epstein-barr-virus-transformed B lymphocytes infiltrating human melanoma

M. Maurer , A. C. Muller , K. Parapatics , W. F. Pickl , C. Wagner et al.
Journal of Proteome Research, 2014, 13, pp.2830--45. ⟨10.1021/pr401270y⟩
Journal articles hal-02168076v1
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Data-Based Radiation Oncology: Design of Clinical Trials in the Toxicity Biomarkers Era

David Azria , Ariane Lapierre , Sophie Gourgou , Dirk de Ruysscher , Jacques Colinge et al.
Frontiers in Oncology, 2017, 7, ⟨10.3389/fonc.2017.00083⟩
Journal articles hal-02294898v1
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Farnesyltransferase inhibition overcomes the adaptive resistance to osimertinib in EGFR-mutant NSCLC

Sarah Figarol , Célia Delahaye , Rémi Gence , Raghda Asslan , Sandra Pagano et al.
2022
Preprints, Working Papers, ... hal-03843955v1
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Targeting a cell state common to triple‐negative breast cancers

Markus Muellner , Barbara Mair , Yasir Ibrahim , Claudia Kerzendorfer , Hannelore Lechtermann et al.
Molecular Systems Biology, 2015, 11 (2), pp.789. ⟨10.15252/msb.20145664⟩
Journal articles hal-02276743v1

Artemisinins Target GABA A Receptor Signaling and Impair α Cell Identity

Jin Li , Tamara Casteels , Thomas Frogne , Camilla Ingvorsen , Christian Honoré et al.
Cell, 2017, 168 (1-2), pp.86-100.e15. ⟨10.1016/j.cell.2016.11.010⟩
Journal articles hal-02284911v1

Building and exploring an integrated human kinase network: global organization and medical entry points

Jacques Colinge , A. Cesar-Razquin , K. Huber , F. P. Breitwieser , P. Majek et al.
Journal of Proteomics, 2014, 107, pp.113--27. ⟨10.1016/j.jprot.2014.03.028⟩
Journal articles hal-02168075v1
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An R package for generic modular response analysis and its application to estrogen and retinoic acid receptor crosstalk

Gabriel Jimenez-Dominguez , Patrice Ravel , Stéphan Jalaguier , Vincent Cavaillès , Jacques Colinge et al.
Scientific Reports, 2021, 11 (1), ⟨10.1038/s41598-021-86544-0⟩
Journal articles hal-03358612v1
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IFIT1 is an antiviral protein that recognises 5'-triphosphate RNA

Giulio Superti-Furga , Andreas Pichlmair , Caroline Lassnig , Christoph L Baumann , Tilmann Bürckstümmer et al.
Nature Immunology, 2011, ⟨10.1038/ni.2048⟩
Journal articles istex hal-00648046v1
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Genome-wide diversity and gene expression profiling of Babesia microti isolates identify polymorphic genes that mediate host-pathogen interactions

J. C. Silva , E. Cornillot , C. Mccracken , S. Usmani-Brown , Ankit Dwivedi et al.
Scientific Reports, 2016, 6, pp.35284. ⟨10.1038/srep35284⟩
Journal articles hal-01940958v1
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The Lipid-Modifying Enzyme SMPDL3B Negatively Regulates Innate Immunity

Leonhard x. Heinz , Christoph l. Baumann , Marielle s. Köberlin , Berend Snijder , Riem Gawish et al.
Cell Reports, 2015, 11 (12), pp.1919-1928. ⟨10.1016/j.celrep.2015.05.006⟩
Journal articles hal-02285811v1

A chemical biology approach identifies AMPK as a modulator of melanoma oncogene MITF

V. Borgdorff , U. Rix , G. E. Winter , M. Gridling , A. C. Muller et al.
Oncogene, 2014, 33, pp.2531--9. ⟨10.1038/onc.2013.185⟩
Journal articles hal-02168079v1

Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy

K. V. Huber , E. Salah , B. Radic , M. Gridling , J. M. Elkins et al.
Nature, 2014, 508, pp.222--7. ⟨10.1038/nature13194⟩
Journal articles hal-02168081v1

Virulence factor NSs of rift valley fever virus recruits the F-box protein FBXO3 to degrade subunit p62 of general transcription factor TFIIH

M. Kainulainen , M. Habjan , P. Hubel , L. Busch , S. Lau et al.
Journal of Virology, 2014, 88, pp.3464--73. ⟨10.1128/JVI.02914-13⟩
Journal articles hal-02168082v1
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A Comprehensive Analysis of the Dynamic Response to Aphidicolin-Mediated Replication Stress Uncovers Targets for ATM and ATMIN

Abdelghani Mazouzi , Alexey Stukalov , André Müller , Doris Chen , Marc Wiedner et al.
Cell Reports, 2016, 15 (4), pp.893-908. ⟨10.1016/j.celrep.2016.03.077⟩
Journal articles hal-02297707v1
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Biallelic loss-of-function mutation in NIK causes a primary immunodeficiency with multifaceted aberrant lymphoid immunity

K. L. Willmann , S. Klaver , F. Dogu , E. Santos-Valente , W. Garncarz et al.
Nature Communications, 2014, 5, pp.5360. ⟨10.1038/ncomms6360⟩
Journal articles hal-02181338v1