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Mutations in INF2 Are a Major Cause of Autosomal Dominant Focal Segmental Glomerulosclerosis

Olivia Boyer , Geneviève Benoit , Olivier Gribouval , Fabien Nevo , Marie-Josèphe Tête , et al.
Journal of the American Society of Nephrology, 2011, 22 (2), pp.239-245. ⟨10.1681/ASN.2010050518⟩
Journal articles hal-02519750v1

Unusual binding of Grb2 protein to a bivalent polyproline-ligand immobilized on a SPR sensor: Intermolecular bivalent binding

Nico de Mol , John A.W. Kruijtzer , Ed Moret , Isabelle Broutin , Rob M.J. Liskamp
Biochimica et Biophysica Acta Proteins and Proteomics, 2013, 1834 (2), pp.524-535. ⟨10.1016/j.bbapap.2012.11.001⟩
Journal articles hal-02519645v1

VEGFR1 domain 2 covalent labeling with horseradish peroxidase: Development of a displacement assay on VEGF

Marie Reille-Seroussi Reille-Seroussi , Jean-François Gaucher , Laure-Anne Cussac , Isabelle Broutin , Michel Vidal , et al.
Analytical Biochemistry, 2017, 530, pp.107-112. ⟨10.1016/j.ab.2017.05.004⟩
Journal articles hal-02519565v1
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Expression, purification, crystallization and preliminary X-ray studies of the outer membrane efflux proteins OprM and OprN from Pseudomonas aeruginosa

Isabelle Broutin , Houssain Benabdelhak , Xavier Moreel , Marie-Bernard Lascombe , Dimitri Lerouge , et al.
Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 2005, 61 (3), pp.315-318. ⟨10.1107/S1744309105005014⟩
Journal articles hal-02150027v1
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Tripartite assembly of RND multidrug efflux pumps

Laetitia Daury , François Orange , Jean-Christophe Taveau , Alice Verchère , Laura Monlezun , et al.
Nature Communications, 2016, 7 (1), ⟨10.1038/ncomms10731⟩
Journal articles hal-02150028v1

Crystal Structure of an Affinity-matured Prolactin Complexed to Its Dimerized Receptor Reveals the Topology of Hormone Binding Site 2

Isabelle Broutin , Jean-Baptiste Jomain , Estelle Tallet , Jan van Agthoven , Bertrand Raynal , et al.
Journal of Biological Chemistry, 2010, 285 (11), pp.8422-8433. ⟨10.1074/jbc.M109.089128⟩
Journal articles hal-02519914v1

The PIR domain of Grb14 is an intrinsically unstructured protein: implication in insulin signaling

Karine Moncoq , Isabelle Broutin , Valéry Larue , Dominique Perdereau , Katia Cailliau , et al.
FEBS Letters, 2003, 554 (3), pp.240-246. ⟨10.1016/s0014-5793(03)01095-0⟩
Journal articles hal-02370396v1

Lysozyme solubility in H 2 O and D 2 O solutions as a function of sodium chloride concentration

I. Broutin , M. Ries-Kautt , A. Ducruix
Journal of Applied Crystallography, 1995, 28 (5), pp.614-617. ⟨10.1107/S0021889895005425⟩
Journal articles istex hal-02520455v1
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Antibiotic export by MexB multidrug efflux transporter is allosterically controlled by a MexA-OprM chaperone-like complex

Marie Glavier , Dhenesh Puvanendran , Dimitri Salvador , Marion Decossas , Gilles Phan , et al.
Nature Communications, 2020, 11 (1), ⟨10.1038/s41467-020-18770-5⟩
Journal articles hal-03006629v1
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Functional Mechanism of the Efflux Pumps Transcription Regulators From Pseudomonas aeruginosa Based on 3D Structures

Karim Housseini B Issa , Gilles Phan , Isabelle Broutin
Frontiers in Molecular Biosciences, 2018, 5, ⟨10.3389/fmolb.2018.00057⟩
Journal articles hal-02150022v1
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Xenon for tunnelling analysis of the efflux pump component OprN

Yvette Véronique Ntsogo Enguéné , Gilles Phan , Cyril Garnier , Arnaud Ducruix , Thierry Prangé , et al.
PLoS ONE, 2017
Journal articles hal-02150038v1
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Solution NMR structure of the SH3 domain of human nephrocystin and analysis of a mutation-causing juvenile nephronophthisis.

Albane Le Maire , Thomas Weber , Sophie Saunier , Isabelle Broutin , Corinne Antignac , et al.
Proteins - Structure, Function and Bioinformatics, 2005, 59 (2), pp.347-55. ⟨10.1002/prot.20344⟩
Journal articles hal-00106409v1

Targeted unlabeled multiple reaction monitoring analysis of cell markers for the study of sample heterogeneity in isolated rat brain cortical microvessels

David Gomez-Zepeda , Catarina Chaves , Méryam Taghi , Philippe Sergent , Wang-Qing Liu , et al.
Journal of Neurochemistry, 2017, 142 (4), pp.597-609. ⟨10.1111/jnc.14095⟩
Journal articles hal-02519576v1

SAXS Study of the PIR Domain from the Grb14 Molecular Adaptor: A Natively Unfolded Protein with a Transient Structure Primer?

K. Moncoq , I. Broutin , C.T. Craescu , P. Vachette , A. Ducruix , et al.
Biophysical Journal, 2004, 87 (6), pp.4056-4064. ⟨10.1529/biophysj.104.048645⟩
Journal articles hal-02520006v1

Structures of cellular retinoic acid binding proteins I and II in complex with synthetic retinoids

Barnali Neel Chaudhuri , Gerard Kleywegt , Isabelle Broutin-L'Hermite , Terese Bergfors , Hans Senn , et al.
Acta crystallographica Section D : Structural biology [1993-..], 1999, 55 (11), pp.1850-1857. ⟨10.1107/s0907444999011026⟩
Journal articles istex hal-02520368v1

Structural and Dynamical Insights into the Opening Mechanism of P. aeruginosa OprM Channel

Gilles Phan , Houssain Benabdelhak , Marie-Bernard Lascombe , Philippe Bénas , Stéphane Réty , et al.
Structure, 2010, 18 (4), pp.507-517. ⟨10.1016/j.str.2010.01.018⟩
Journal articles hal-02519908v1
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1.8 A structure of Hypoderma lineatum collagenase: a member of the serine proteinase family.

Isabelle Broutin , Bernadette Arnoux , Claude Riche , Anne Lecroisey , Borivoj Keil , et al.
Acta crystallographica Section D : Structural biology [1993-..], 1996, 52 (Pt 2), pp.380-92. ⟨10.1107/S090744499501184X⟩
Journal articles pasteur-00376448v1

Carbapenem resistance in cystic fibrosis strains of Pseudomonas aeruginosa as a result of amino acid substitutions in porin OprD

Charlotte Richardot , Patrick Plesiat , Damien Fournier , Laura Monlezun , Isabelle Broutin , et al.
International Journal of Antimicrobial Agents, 2015, 45 (5), pp.529 - 532. ⟨10.1016/j.ijantimicag.2014.12.029⟩
Journal articles hal-01695313v1

Targeted unlabeled multiple reaction monitoring analysis of cell markers for the study of sample heterogeneity in isolated rat brain cortical microvessels

David Gomez-Zepeda , Catarina Chaves , Méryam Taghi , Philippe Sergent , Wang-Qing Liu , et al.
Journal of Neurochemistry, 2017, 142 (4), pp.597-609. ⟨10.1111/jnc.14095⟩
Journal articles hal-03039018v1
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New OprM structure highlighting the nature of the N-terminal anchor

Laura Monlezun , Gilles Phan , Houssain Benabdelhak , Marie-Bernard Lascombe , Véronique y N Enguéné , et al.
Frontiers in Microbiology, 2015, 6, ⟨10.3389/fmicb.2015.00667⟩
Journal articles hal-02150031v1
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Focus on the Outer Membrane Factor OprM, the Forgotten Player from Efflux Pumps Assemblies

Gilles Phan , Martin Picard , Isabelle Broutin
Antibiotics, 2015, 4 (4), pp.544-566. ⟨10.3390/antibiotics4040544⟩
Journal articles hal-02150041v1
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In vitro transport activity of the fully assembled MexAB-OprM efflux pump from Pseudomonas aeruginosa

Alice Verchère , Manuela Dezi , Vladimir Adrien , Isabelle Broutin , Martin Picard
Nature Communications, 2015, 6 (1), ⟨10.1038/ncomms7890⟩
Journal articles hal-02150070v1

1.7 Å X-ray structure of space-grown collagenase crystals

I. Broutin-L'Hermite , M. Ries-Kautt , A. Ducruix
Acta crystallographica Section D : Structural biology [1993-..], 2000, 56 (3), pp.376-378. ⟨10.1107/s0907444999016789⟩
Journal articles istex hal-02520355v1

Structural and Thermodynamic Bases for the Design of Pure Prolactin Receptor Antagonists

Jean-Baptiste Jomain , Estelle Tallet , Isabelle Broutin , Sylviane Hoos , Jan van Agthoven , et al.
Journal of Biological Chemistry, 2007, 282 (45), pp.33118-33131. ⟨10.1074/jbc.M704364200⟩
Journal articles hal-02519923v1

Constitutive activation of MexT by amino acid substitutions results in MexEF-OprN overproduction in clinical isolates of Pseudomonas aeruginosa

Paulo Juarez , Isabelle Broutin , Christophe Bordi , Patrick Plesiat , Catherine Llanes
Antimicrobial Agents and Chemotherapy, 2018, ⟨10.1128/AAC.02445-17⟩
Journal articles hal-01770232v1

Identification of Polyproline II Regions Derived From the Proline-Rich Nuclear Receptor Coactivators PNRC and PNRC2: New Insights for ERα Coactivator Interactions.

C. Byrne , E. Miclet , I. Broutin , D. Gallo , V. Pelekanou , et al.
Chirality, 2013, 25 (10), pp.628-642. ⟨10.1002/chir.22188⟩
Journal articles istex hal-00851031v1
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INF2 mutations in Charcot-Marie-Tooth disease with glomerulopathy.

Olivia Boyer , Fabien Nevo , Emmanuelle Plaisier , Benoît Funalot , Olivier Gribouval , et al.
New England Journal of Medicine, 2011, 365 (25), pp.2377-88. ⟨10.1056/NEJMoa1109122⟩
Journal articles inserm-00919173v1

Stoichiometry of the MexA-OprM binding, as investigated by blue native gel electrophoresis

Yann Ferrandez , Laura Monlezun , Gilles Phan , Houssain Benabdelhak , Philippe Bénas , et al.
Electrophoresis, 2012, 33 (8), pp.1282-1287. ⟨10.1002/elps.201100541⟩
Journal articles istex hal-02519724v1

Crystal structures of the SH2 domain of grb2: highlight on the binding of a new high-affinity inhibitor

Pierre Nioche , Wang-Qing Liu , Isabelle Broutin , Franck Charbonnier , Marie-Thérèse Latreille , et al.
Journal of Molecular Biology, 2002, 315 (5), pp.1167-1177. ⟨10.1006/jmbi.2001.5299⟩
Journal articles istex hal-02520104v1

Grb2 promotes reinitiation of meiosis in Xenopus oocytes

Katia Cailliau , Edith Browaeys-Poly , Isabelle Broutin-L'Hermite , Pierre Nioche , Christiane Garbay , et al.
Cellular Signalling, 2001, 13 (1), pp.51-55. ⟨10.1016/s0898-6568(00)00138-8⟩
Journal articles istex hal-02520116v1