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Comparison of TP53 mutations screening by functional assay of separated allele in yeast and next-generation sequencing in myelodysplastic syndromes

Cécile Bally , Aline Renneville , Claude Preudhomme , Matthieu Legrand , Lionel Adès , et al.
Leukemia Research, 2015, 39 (11), pp.1214-1219. ⟨10.1016/j.leukres.2015.07.001⟩
Journal articles hal-03653842v1

Therapy-induced selective loss of leukemia-initiating activity in murine adult T cell leukemia.

Hajj El H. , M. El-Sabban , H. Hasegawa , G. Zaatari , J. Ablain , et al.
Journal of Experimental Medicine, 2010, 207 (13), pp.2785-2792. ⟨10.1084/jem.20101095⟩
Journal articles hal-00547378v1

PML nuclear bodies and neuronal intranuclear inclusion in polyglutamine diseases

Junko Takahashi , Hiroto Fujigasaki , Kiyoshi Iwabuchi , Amalia Bruni , Toshiki Uchihara , et al.
Neurobiology of Disease, 2003, 13 (3), pp.230-237. ⟨10.1016/s0969-9961(03)00080-9⟩
Journal articles istex hal-03503149v1

Deletion 6q drives T-cell leukemia progression by ribosome modulation

Stéphanie Gachet , Tiama El-Chaar , David Avran , Eulàlia Genescà , Frédéric Catez , et al.
Cancer Discovery, 2018, ⟨10.1158/2159-8290.CD-17-0831⟩
Journal articles hal-01908797v1

Isolation and characterization of an equine foamy virus.

H Tobaly-Tapiero , B Bittoun , M Neves , M. Guillemin , H Lecellier , et al.
Journal of Virology, 2000, 74 (9), pp.4064-73. ⟨10.1128/jvi.74.9.4064-4073.2000⟩
Journal articles hal-02106474v1
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PML/RARα Destabilization by Hyperthermia: A New Model for Oncogenic Fusion Protein Degradation?

Hsin Chieh Wu , Domitille Rérolle , Hugues de Thé
Blood Cancer Discovery, 2021, 2 (4), pp.300-301. ⟨10.1158/2643-3230.BCD-21-0071⟩
Journal articles hal-04055409v1
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Yolk sac-derived Pdcd11-positive cells modulate zebrafish microglia differentiation through the NF-κB-Tgfβ1 pathway

Ruimeng Yang , Ming Zhan , Miaomiao Guo , Hao Yuan , Yiqin Wang , et al.
Cell Death and Differentiation, 2021, 28 (1), pp.170-183. ⟨10.1038/s41418-020-0591-3⟩
Journal articles hal-03428097v1

RNF4 regulates zebrafish granulopoiesis through the DNMT1-C/EBPα axis

Luxiang Wang , Xiaohui Liu , Haihong Wang , Hao Yuan , Saijuan Chen , et al.
FASEB Journal, 2018, 32 (9), pp.4930-4940. ⟨10.1096/fj.201701450RR⟩
Journal articles hal-02350270v1

Combined treatment with arsenic trioxide and all-transretinoic acid in patients with relapsed acute promyelocytic leukemia

E. Raffoux , P. Rousselot , J. Poupon , Daniel M.T. , B. Cassinat , et al.
Journal of Clinical Oncology, 2003, 21, pp.2326-2334
Journal articles hal-00093389v1

Lessons taught by acute promyelocytic leukemia cure

Hugues de Thé
The Lancet, 2015, 386 (9990), pp.247-248. ⟨10.1016/S0140-6736(15)61278-8⟩
Journal articles hal-03653861v1

A PML/retinoic acid receptor alpha fusion transcript is constantly detected by RNA-based polymerase chain reaction in acute promyelocytic leukemia

Sylvie Castaigne , Nicole Balitrand , Hughes de Thé , Anne Dejean , Laurent Degos , et al.
Blood, 1992, 79 (12), pp.3110-3115. ⟨10.1182/blood.V79.12.3110.3110⟩
Journal articles pasteur-03238312v1
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Molecular apocrine breast cancers are aggressive estrogen receptor negative tumors overexpressing either HER2 or GCDFP15.

Jacqueline Lehmann-Che , Anne-Sophie Hamy , Raphaël Porcher , Marc Barritault , Fatiha Bouhidel , et al.
Breast Cancer Research, 2013, 15 (3), pp.R37. ⟨10.1186/bcr3421⟩
Journal articles inserm-00850498v1

All-trans retinoic acid/As203 combination yields a high quality remission and survival in newly disgnosed acute promyelocytic leukemia.

Z.X. Shen , Shi Z.Z. , J. Fang , Gu B.W. , Li J.M. , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2004, 101, pp.5328-5335
Journal articles hal-00102121v1

Promyelocytic Leukemia Protein, a Protein at the Crossroad of Oxidative Stress and Metabolism

Sarah Tessier , Natalia Martin-Martin , Hugues de Thé , Arkaitz Carracedo , Valérie Lallemand-Breitenbach
Antioxidants and Redox Signaling, 2017, 26 (9), pp.432-444. ⟨10.1089/ars.2016.6898⟩
Journal articles hal-02441961v1
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Irf2bp2a regulates terminal granulopoiesis through proteasomal degradation of Gfi1aa in zebrafish

Shuo Gao , Zixuan Wang , Luxiang Wang , Haihong Wang , Hao Yuan , et al.
PLoS Genetics, 2021, 17 (8), pp.e1009693. ⟨10.1371/journal.pgen.1009693⟩
Journal articles hal-04054293v1

Amyotrophic lateral sclerosis with neuronal intranuclear protein inclusions

D. Seilhean , J. Takahaschi , El Hachimi K.H. , H. Fujigasaki , A.S. Lebre , et al.
Acta Neuropathologica, 2004, 108, pp.81-87
Journal articles hal-00098191v1

TAMM41 is required for heart valve differentiation via regulation of PINK-PARK2 dependent mitophagy

Rui Meng Yang , Jiong Tao , Ming Zhan , Hao Yuan , Hai Hong Wang , et al.
Cell Death and Differentiation, 2019, 26 (11), pp.2430-2446. ⟨10.1038/s41418-019-0311-z⟩
Journal articles hal-02350278v1

TP53 mutation-correlated genes predict the risk of tumor relapse and identify MPS1 as a potential therapeutic kinase in TP53-mutated breast cancers

B. Gyorffy , G. Bottai , J. Lehmann-Che , G. Keri , L. Orfi , et al.
Molecular oncology, 2014, 8 (3), pp.508-19. ⟨10.1016/j.molonc.2013.12.018⟩
Journal articles hal-03653831v1

Prognostic value of TP53 gene mutations in myelodysplastic syndromes and acute myeloid leukemia treated with azacitidine

C. Bally , L. Ades , A. Renneville , M. Sebert , V. Eclache , et al.
LEUKEMIA RESEARCH, 2014, 38 (7), pp.751-5. ⟨10.1016/j.leukres.2014.03.012⟩
Journal articles hal-03653835v1

Activation of a promyelocytic leukemia-tumor protein 53 axis underlies acute promyelocytic leukemia cure

J. Ablain , K. Rice , H. Soilihi , A. De Reynies , S. Minucci , et al.
Nature Medicine, 2014, 20 (2), pp.167-174. ⟨10.1038/nm.3441⟩
Journal articles hal-03653839v1

Oncologie cellulaire et moléculaire

Hugues de Thé
L’annuaire du Collège de France. Cours et travaux, 2016, 115, pp.309-318. ⟨10.4000/annuaire-cdf.12548⟩
Journal articles hal-03653851v1

Dual origin of relapses in retinoic-acid resistant acute promyelocytic leukemia

Jacqueline Lehmann-Che , Cécile Bally , Eric Letouzé , Caroline Berthier , Hao Yuan , et al.
Nature Communications, 2018, 9 (1), pp.2047. ⟨10.1038/s41467-018-04384-5⟩
Journal articles hal-03653853v1

Identification of IRF8 as a potent tumor suppressor in murine acute promyelocytic leukemia

Coline Gaillard , Sangeetha Surianarayanan , Trevor Bentley , Matthew R. Warr , Briana Fitch , et al.
Blood Advances, 2018, 2 (19), pp.2462--2466. ⟨10.1182/bloodadvances.2018018929⟩
Journal articles hal-03653863v1

Transcription and methylation analyses of preleukemic promyelocytes indicate a dual role for PML/RARA in leukemia initiation

Coline Gaillard , Taku A. Tokuyasu , Galit Rosen , Jason Sotzen , Adeline Vitaliano-Prunier , et al.
Haematologica, 2015, 100 (8), pp.1064-1075. ⟨10.3324/haematol.2014.123018⟩
Journal articles hal-03653866v1

L’oncologie : de l’empirisme à la biologie intégrée : Leçon inaugurale prononcée le jeudi 8 janvier 2015

Hugues de Thé
Collège de France, 252, 2016, Leçons inaugurales, 978-2-7226-0426-1
Books hal-03653930v1

Oncologie cellulaire et moléculaire

Hugues de Thé
Other publications hal-03653987v1
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A refined molecular taxonomy of breast cancer.

Michael Guedj , Laëtitia Marisa , Aurélien de Reynies , Béatrice Orsetti , Renaud Schiappa , et al.
Oncogene, 2012, 31 (9), pp.1196-206. ⟨10.1038/onc.2011.301⟩
Journal articles inserm-00611752v1

The PML-retinoic acid receptor alpha translocation converts the receptor from an inhibitor to a retinoic acid-dependent activator of transcription factor AP-1

Vassilis Doucas , Jeremy P. Brockes , Moshe Yaniv , Hugues de Thé , Anne Dejean
Proceedings of the National Academy of Sciences of the United States of America, 1993, 90 (20), pp.9345-9349. ⟨10.1073/pnas.90.20.9345⟩
Journal articles pasteur-03238309v1

A novel steroid thyroid hormone receptor-related gene inappropriately expressed in human hepatocellular carcinoma

Hugues de Thé , Agnès Marchio , Pierre Tiollais , Anne Dejean
Nature, 1987, 330 (6149), pp.667-670. ⟨10.1038/330667a0⟩
Journal articles istex pasteur-03238341v1
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Promyelocytic Leukemia Protein (PML) Controls Listeria monocytogenes Infection.

David Ribet , Valérie Lallemand-Breitenbach , Omar Ferhi , Marie-Anne Nahori , Hugo Varet , et al.
mBio, 2017, 8 (1), pp.1-16. ⟨10.1128/mBio.02179-16⟩
Journal articles pasteur-01433079v1