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The urotensin II receptor relays key neurobiological mechanisms in subarachnoid hemorrhage: Efficacy of pathway-targeted drugs on long-term brain deficits

Martin Pedard , Martine Dubois , Roxane Gruel , Laurence Desrues , David Godefroy , et al.
Congrès annuel du GDR-GPCR, Oct 2019, Montpellier, France
Conference papers hal-02418166v1

Re-expression of the neurodevelopmental protein filamin A in glioblastoma enhance tumor proliferation and invasiveness

Alexandre Mutel , Céline Lecointre , Paul Dembele K. , Pierre-Olivier Guichet , Laurent Mouchard , et al.
NeuroFrance, Marseille, May 22-24, 2019, May 2019, Marseille, France
Poster communications hal-02335534v1

Improvement of survival and cognitive functions by means of a local hydrogel trap in a mouse model of glioblastoma resection

Emmanuel Laillet de Montullé , Martine Dubois , François-Xavier Ferracci , Alexandre Mutel , Paul Dembele K. , et al.
14th EANO annual meeting, Sep 2019, Lyon, France
Poster communications hal-02335569v1

Impact of hormone-therapy used in CRPC patients: evaluation of abiraterone acetate/prednisone or enzalutamide on activity and cognitive functions in aged castrated mice

Martine Dubois , Tareq Al Sagheer , Cynthia Campart , Laurence Desrues , Marie Lange , et al.
ASCO annual meeting, May 2019, Chicago, United States
Poster communications hal-02335627v1

Control of membrane GPCR signaling by Filamin A : implication in high-grade glioma development

Alexandre Mutel , Céline Lecointre , Paul Dembele Kleouforo , Pierre-Olivier Guichet , Laurent Mouchard , et al.
NeuroFrance, May 2017, Bordeaux, France
Poster communications hal-02340413v1

Signaling switch of a vasoactive peptide GPCR: Prototypic chemotaxic mechanism involved in glioma

Vadim Le Joncour , Céline Lecointre , Pierre-Olivier Guichet , Nicolas Perzo , Laurence Desrues , et al.
19th World Congress on Advances in Oncology and 17th International Symposium on Molecular Medicine, Oct 2014, Athènes, Greece. pp.S62-S62
Conference papers hal-02295211v1

Modulation of autophagic activity by chemotactic GPVRs controls the invasive potential of glioblastoma cells

Pierre-Mickaël Coly , Nicolas Perzo , Vadim Le Joncour , Céline Lecointre , Marie-Thérèse Schouft , et al.
1ère Journée Normande de Recherche Biomédicale IRIB-ICORE, Sep 2016, Rouen, France
Conference papers hal-02340048v1

Neurodevelopmental long-term outcome in children with hydrocephalus requiring neonatal surgical treatment

A. Melot , A. Labarre , C. Vanhulle , S. Rondeau , M. Brasseur , et al.
Neurochirurgie, 2016, 62 (2), pp.94-99. ⟨10.1016/j.neuchi.2015.10.009⟩
Journal articles hal-02367756v1

The octadecaneuropeptide ODN prevents 6-hydroxydopamine-induced apoptosis of cerebellar granule neurons through a PKC-MAPK-dependent pathway

Hadhemi Kaddour , Yosra Hamdi , David Vaudry , Magalie Basille , Laurence Desrues , et al.
Journal of Neurochemistry, 2013, 125 (4), pp.620-633. ⟨10.1111/jnc.12140⟩
Journal articles hal-01962763v1

GPCR-induced repression of autophagy in glioblastoma cells: impact on lamellipodium expansion and chemotactic migration

Daniele Campisi , Pierre-Mickaël Coly , Hélène Castel , Pierrick Gandolfo , Fabrice Morin
11èmes journées scientifiques du Cancéropôle Nord-Ouest, May 2018, Deauville, France
Poster communications hal-02338919v1

Proline in 2.58 of chemokine and vasoactive peptide G-protein coupled receptors: A structural determinant in chemotaxis?

Laurence Desrues , Eilen Joubert Jane , Nicolas Perzo , Laure Guilhaudis , Isabelle Milazzo , et al.
Annual Meeting of the LARC-Neuroscience network (21, 2017), Oct 2017, Lille, France
Poster communications hal-02341500v1

Endogenous Expression of ODN-Related Peptides in Astrocytes Contributes to Cell Protection Against Oxidative Stress: Astrocyte-Neuron Crosstalk Relevance for Neuronal Survival

Ikram Ghouili , Seyma Bahdoudi , Fabrice Morin , Fatma Amri , Yosra Hamdi , et al.
Molecular Neurobiology, 2018, 55 (6), pp.4596-4611. ⟨10.1007/s12035-017-0630-3⟩
Journal articles hal-02280049v1

Chimiothérapie et autres modèles animaux

Hélène Castel
Onconeurotox, Sep 2020, e-congrés, France
Conference papers hal-02942826v1

GPCR-induced repression of autophagy in glioblastoma cells: impact on lamellipodium expansion and chemotactic migration.

Daniele Campisi , Pierre-Michaël Coly , Hélène Castel , Pierrick Gandolfo , Fabrice Morin
22ème journée du réseau LARC-Neurosciences, Oct 2018, Rouen, France
Conference papers hal-02305860v1

L’effet pro-migratoire des RCPG chimiotactiques nécessite la modulation de l’autophagie via la voie calpaïne/ATG5: rôle potentiel dans l’invasion des cellules de gliome

Pierre-Mickaël Coly , Nicolas Perzo , Vadim Le Joncour , Céline Lecointre , Marie-Christine Tonon , et al.
8èmes Journées Scientifiques du Cancéropôle Nord-Ouest, Jun 2015, Deauville, France
Poster communications hal-02352356v1

Mise en évidence de troubles cognitifs après traitement avec un anti-angiogénique dans un modèle murin préclinique

Martine Dubois , Benjamin Quignon , Marie-Christine Tonon , Pierrick Gandolfo , Olivier Wurtz , et al.
8èmes Journées du Canceropole Nord-Ouest, Jun 2015, Deauville, France
Poster communications hal-02351553v1

Mettre au point des stratégies de recherche originales pour combattre le cancer du cerveau

Hélène Castel
Conférence grand public, Assemblée générale caisse locale du Crédit Agricole, Feb 2017, Bosc le Hard, France
Conference papers hal-02453169v1

Répression de l’autophagie par les récepteurs chimiotactiques de type RCPG: impact sur les propriétés invasives des cellules de gliomes

Daniele Campisi , Pierre-Michaël Coly , Laurence Desrues , Hélène Castel , Pierrick Gandolfo , et al.
12èmes journées scientifiques du Cancéropôle Nord-Ouest, May 2019, Deauville, France
Conference papers hal-02301486v1
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Cancer-related cognitive impairment in non-CNS cancer patients: Targeted review and future action plans in Europe

Charlotte Sleurs , Ali Amidi , Lisa M Wu , David Kiesl , Philipp Zimmer , et al.
Critical Reviews in Oncology/Hematology, 2022, pp.103859. ⟨10.1016/j.critrevonc.2022.103859⟩
Journal articles inserm-03822953v1
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Impact of new generation hormone-therapy on cognitive function in elderly patients treated for a metastatic prostate cancer: Cog-Pro trial protocol

Marie Lange , Heidi Laviec , Hélène Castel , Natacha Heutte , Alexandra Leconte , et al.
BMC Cancer, 2017, 17 (1), pp.549. ⟨10.1186/s12885-017-3534-8⟩
Journal articles inserm-01582168v1
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Decline in Cognitive Function in Older Adults With Early-Stage Breast Cancer After Adjuvant Treatment

Marie Lange , Natacha Heutte , Olivier Rigal , Sabine Noal , Jean-Emmanuel Kurtz , et al.
Oncologist, 2016, pii: theoncologist.2016-0014. ⟨10.1634/theoncologist.2016-0014⟩
Journal articles inserm-01369848v1

Chemotaxic signaling of urotensin II vasoactive peptide receptor in glioma

Hélène Castel , Vadim Le Joncour , Céline Lecointre , Pierre-Olivier Guichet , Nicolas Perzo , et al.
TC2N final meeting, Jun 2014, Gent, Belgium
Conference papers hal-02299520v1

Urotensin II system as a potential therapeutic target in septic shock: human and experimental studies

Thomas Clavier , Emmanuel Besnier , Laurence Desrues , Fabienne Tamion , Vincent Compère , et al.
Euroanaesthesia 2017 Congress, Jun 2017, Geneva, Switzerland
Poster communications hal-02345006v1

Cognitive Changes After Adjuvant Treatment in Older Adults with Early‐Stage Breast Cancer

Marie Lange , Natacha Heutte , Sabine Noal , Olivier Rigal , Jean-Emmanuel Kurtz , et al.
Oncologist, 2019, 24 (1), pp.62-68. ⟨10.1634/theoncologist.2017-0570⟩
Journal articles inserm-02097848v1

Impact of a key ancestral deletion in chemokine and vasoactive peptide receptors on chemotaxis

Jane Eileen Joubert , Laurence Desrues , Nicolas Perzo , Céline Lecointre , Laure Guilhaudis , et al.
Colloque de la Société des neurosciences (12, 2015), May 2015, Montpellier, France
Poster communications hal-02349910v1
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Down-Regulation of GABAA Receptor via Promiscuity with the Vasoactive Peptide Urotensin II Receptor. Potential Involvement in Astrocyte Plasticity

Laurence Desrues , Thomas Lefebvre , Céline Lecointre , Marie-Thérèse Schouft , Jérôme Leprince , et al.
PLoS ONE, 2012, 7 (5), pp.e36319. ⟨10.1371/journal.pone.0036319⟩
Journal articles hal-01962706v1
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The vasoactive peptides urotensin II and urotensin II-related peptide regulate astrocyte activity through common and distinct mechanisms. Involvement in cell proliferation

Marie Jarry , Mickael Diallo , Céline Lecointre , Laurence Desrues , Tursonjan Tokay , et al.
Biochemical Journal, 2010, 428 (1), pp.113-124. ⟨10.1042/BJ20090867⟩
Journal articles hal-00479207v1

Pre-clinical animal models and targeted therapies on cognition: Direct Impact of the PI3K inhibitor buparlisib

Martine Dubois , Marie-Christine Tonon , Nicolas Perzo , Pierrick Gandolfo , Pascal Hilber , et al.
19th Annual meeting of the LARC-Neuroscience network, Nov 2015, Amiens, France
Poster communications hal-02351458v1

Expression plasticity of chemotactic GPCRs and signalling commutators controls glioblastoma invasion and survival

Hélène Castel
Colloque annuel de la SCMC, Mar 2020, Paris, France
Conference papers hal-02452731v1

Biochemical and functional characterization of high-affinity urotensin II receptors in rat cortical astrocytes

Hélène Castel , Mickael Diallo , David Chatenet , Jérôme Leprince , Laurence Desrues , et al.
Journal of Neurochemistry, 2006, 99 (2), pp.582-595. ⟨10.1111/j.1471-4159.2006.04130.x⟩
Journal articles hal-01960748v1