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Inhibition of CD1 Expression in Human Dendritic Cells during Intracellular Infection with Leishmania donovani

Joseph Amprey , Gerald F Späth , Steven Porcelli
Infection and Immunity, 2004, 72 (1), pp.589-592. ⟨10.1128/iai.72.1.589-592.2004⟩
Journal articles pasteur-03109226v1

Characterization of a Defensin from the Sand Fly Phlebotomus duboscqi Induced by Challenge with Bacteria or the Protozoan Parasite Leishmania major

Nathalie Boulanger , Carl Lowenberger , Petr Volf , Raul Ursic , Lucie Sigutova , et al.
Infection and Immunity, 2004, 72 (12), pp.7140-7146. ⟨10.1128/IAI.72.12.7140-7146.2004⟩
Journal articles pasteur-03109311v1
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Dynamic imaging reveals surface exposure of virulent Leishmania amastigotes during pyroptosis of infected macrophages

Thibault Rosazza , Hervé Lecoeur , Thierry Blisnick , Maryse Moya-Nilges , Pascale Pescher , et al.
Journal of Cell Science, 2020, pp.jcs.242776. ⟨10.1242/jcs.242776⟩
Journal articles pasteur-02779320v1
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Modulation of Aneuploidy in Leishmania donovani during Adaptation to Different In Vitro and In Vivo Environments and Its Impact on Gene Expression

Franck Dumetz , H. Imamura , M. Sanders , V. Seblova , J. Myskova , et al.
mBio, 2017, pp.e00599-17. ⟨10.1128/mBio.00599-17⟩
Journal articles pasteur-01974269v1
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Effect of clinically approved HDAC inhibitors on Plasmodium, Leishmania and Schistosoma parasite growth.

Ming Jang Chua , Megan S J Arnold , Weijun Xu , Julien Lancelot , Suzanne Lamotte , et al.
International journal for parasitology. Drugs and drug resistance, 2017, 7 (1), pp.42-50. ⟨10.1016/j.ijpddr.2016.12.005⟩
Journal articles pasteur-01451045v1

Simultaneous multi-parametric analysis of Leishmania and of its hosting mammal cells: A high content imaging-based method enabling sound drug discovery process

Claire-Lise Forestier , Gerald F Späth , Eric Prina , Sreekanth Dasari
Microbial Pathogenesis, 2015, 88, pp.103-108. ⟨10.1016/j.micpath.2014.10.012⟩
Journal articles pasteur-01433404v1

Phosphoproteomic analysis of wild-type and antimony-resistant Leishmania braziliensis lines by 2D-DIGE technology

Douglas de Souza Moreira , Pascale Pescher , Christine Laurent , Pascal Lenormand , Gerald F Späth , et al.
Proteomics, 2015, 15 (17), pp.2999-3019. ⟨10.1002/pmic.201400611⟩
Journal articles istex pasteur-01433409v1
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Regulation dynamics of Leishmania differentiation: deconvoluting signals and identifying phosphorylation trends

Polina Tsigankov , Pier Federico Gherardini , Manuela Helmer-Citterich , Gerald F Späth , Peter J. Myler , et al.
Molecular and Cellular Proteomics, 2014, 13 (7), pp.1787-1799. ⟨10.1074/mcp.M114.037705⟩
Journal articles pasteur-01433413v1

Enrichment of Leishmania donovani ATP-binding proteins using a staurosporine capture compound.

Olivier Leclercq , Kathrin Bartho , Erik Duelsner , Lisa von Kleist , Pier Federico Gherardini , et al.
Journal of Proteomics, 2013, 86, pp.97-104. ⟨10.1016/j.jprot.2013.05.002⟩
Journal articles pasteur-01433419v1

Identification of Leishmania-specific protein phosphorylation sites by LC-ESI-MS/MS and comparative genomics analyses

Sonia Hem , Pier Federico Gherardini , José Osorio y Fortéa , Veronique Hourdel , Miguel A. Morales , et al.
Proteomics, 2010, 10 (21), pp.3868-3883. ⟨10.1002/pmic.201000305⟩
Journal articles istex pasteur-01433567v1
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Nitric oxide controls proliferation of Leishmania major by inhibiting the recruitment of permissive host cells

Pauline Formaglio , Mohamad Alabdullah , Anastasios Siokis , Juliane Handschuh , Ina Sauerland , et al.
Immunity, 2021, 54 (12), pp.2724-2739.e10. ⟨10.1016/j.immuni.2021.09.021⟩
Journal articles pasteur-03512641v1

Leishmania major intracellular survival is not altered in SHP-1 deficient mev or CD45−/− mice

Gerald F Späth , Mary Ann Mcdowell , Stephen Beverley
Experimental Parasitology, 2008, 120 (3), pp.275-279. ⟨10.1016/j.exppara.2008.07.003⟩
Journal articles pasteur-03109079v1
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Cyclosporin A treatment of Leishmania donovani reveals stage-specific functions of cyclophilins in parasite proliferation and viability

Wai-Lok Yau , Thierry Blisnick , Jean-François Taly , Manuela Helmer-Citterich , Cordelia Schiene-Fischer , et al.
PLoS Neglected Tropical Diseases, 2010, 4 (6), pp.e729. ⟨10.1371/journal.pntd.0000729⟩
Journal articles pasteur-01433566v1

Apoptotic marker expression in the absence of cell death in staurosporine-treated Leishmania donovani

Aude L. Foucher , Najma Rachidi , Sarah Gharbi , Thierry Blisnick , Philippe Bastin , et al.
Antimicrobial Agents and Chemotherapy, 2013, 57 (3), pp.1252-1261. ⟨10.1128/AAC.01983-12⟩
Journal articles pasteur-01433417v1
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Networking the Leishmania research community for the development of novel anti-leishmanial intervention strategies

Gerald F Späth
Institut Pasteur International Network Annual Scientific Meeting, Nov 2010, Hong-Kong, Hong Kong SAR China. pp.L8, ⟨10.1186/1753-6561-5-S1-L8⟩
Conference papers inserm-00663865v1
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The Crystal Structure of the MAP Kinase LmaMPK10 from Leishmania Major Reveals Parasite-Specific Features and Regulatory Mechanisms.

Sofía Horjales , Dirk Schmidt-Arras , Ramiro Rodriguez Limardo , Olivier Leclercq , Gonzalo Obal , et al.
Structure, 2012, epub ahead of print. ⟨10.1016/j.str.2012.07.005⟩
Journal articles pasteur-00727033v1
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Transgenic analysis of the Leishmania MAP kinase MPK10 reveals an auto-inhibitory mechanism crucial for stage-regulated activity and parasite viability.

Mathieu Cayla , Najma Rachidi , Olivier Leclercq , Dirk Schmidt-Arras , Heidi Rosenqvist , et al.
PLoS Pathogens, 2014, 10 (9), pp.e1004347. ⟨10.1371/journal.ppat.1004347⟩
Journal articles pasteur-01109591v1
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Post-transcriptional regulation of Leishmania fitness gain

Laura Piel , K. Shanmugha Rajan , Giovanni Bussotti , Hugo Varet , Rachel Legendre , et al.
Preprints, Working Papers, ... pasteur-03210825v1
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Identification of the Host Substratome of Leishmania-Secreted Casein Kinase 1 Using a SILAC-Based Quantitative Mass Spectrometry Assay

Despina Smirlis , Florent Dingli , Valentin Sabatet , Aileen Roth , Uwe Knippschild , et al.
Frontiers in Cell and Developmental Biology, 2022, 9, pp.800098. ⟨10.3389/fcell.2021.800098⟩
Journal articles pasteur-03524218v1

Pharmacological assessment defines Leishmania donovani casein kinase 1 as a drug target and reveals important functions in parasite viability and intracellular infection

Najma Rachidi , Jean François Taly , Emilie Durieu , Olivier Leclercq , Nathalie Aulner , et al.
Antimicrobial Agents and Chemotherapy, 2014, 58 (3), pp.1501-1515. ⟨10.1128/AAC.02022-13⟩
Journal articles pasteur-01433412v1

Identification of a Compensatory Mutant (lpg2−REV) of Leishmania major Able To Survive as Amastigotes within Macrophages without LPG2-Dependent Glycoconjugates and Its Significance to Virulence and Immunization Strategies

Gerald F Späth , Lon-Fye Lye , Hiroaki Segawa , Salvatore Turco , Stephen Beverley
Infection and Immunity, 2004, 72 (6), pp.3622-3627. ⟨10.1128/IAI.72.6.3622-3627.2004⟩
Journal articles pasteur-03109413v1

Exoerythrocytic development of Plasmodium gallinaceum in the White Leghorn chicken

Ute Frevert , Gerald Späth , Herman Yee
International Journal for Parasitology, 2008, 38 (6), pp.655-672. ⟨10.1016/j.ijpara.2007.09.012⟩
Journal articles pasteur-03109089v1
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PhosTryp: a phosphorylation site predictor specific for parasitic protozoa of the family trypanosomatidae.

Antonio Palmeri , Pier Federico Gherardini , Polina Tsigankov , Gabriele Ausiello , Gerald F Späth , et al.
BMC Genomics, 2011, 12 (1), pp.614. ⟨10.1186/1471-2164-12-614⟩
Journal articles pasteur-00673514v1
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Probing druggability and biological function of essential proteins in Leishmania combining facilitated null mutant and plasmid shuffle analyses

Mariko Dacher , Miguel A Morales , Pascale Pescher , Olivier Leclercq , Najma Rachidi , et al.
Molecular Microbiology, 2014, 93, pp.146-166. ⟨10.1111/mmi.12648⟩
Journal articles hal-01178772v1

Quantitative proteome profiling informs on phenotypic traits that adapt Leishmania donovani for axenic and intracellular proliferation

Pascale Pescher , Thierry Blisnick , Philippe Bastin , Gerald F Späth
Cellular Microbiology, 2011, 13 (7), pp.978-991. ⟨10.1111/j.1462-5822.2011.01593.x⟩
Journal articles pasteur-01433560v1

Imaging host cell-Leishmania interaction dynamics implicates parasite motility, lysosome recruitment, and host cell wounding in the infection process

Claire-Lise Forestier , Christophe Machu , Celine Loussert , Pascale Pescher , Gerald F Späth
Cell Host and Microbe, 2011, 9 (4), pp.319-330. ⟨10.1016/j.chom.2011.03.011⟩
Journal articles pasteur-01433561v1
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Leishmania Donovani 90 kD Heat Shock Protein - Impact of Phosphosites on Parasite Fitness, Infectivity and Casein Kinase Affinity

Antje Hombach-Barrigah , Katharina Bartsch , Despina Smirlis , Heidi Rosenqvist , Andrea Macdonald , et al.
Scientific Reports, 2019, 9 (1), pp.5074. ⟨10.1038/s41598-019-41640-0⟩
Journal articles pasteur-02874587v1
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Leishmania dual‐specificity tyrosine‐regulated kinase 1 (DYRK1) is required for sustaining Leishmania stationary phase phenotype

Vinícius Pinto Costa Rocha , Mariko Dacher , Simon Alan Young , Foteini Kolokousi , Antonia Efstathiou , et al.
Molecular Microbiology, 2020, 113 (5), pp.983-1002. ⟨10.1111/mmi.14464⟩
Journal articles pasteur-03110168v1
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Characterisation of Casein Kinase 1.1 in Leishmania donovani Using the CRISPR Cas9 Toolkit

Daniel Martel , Tom Beneke , Eva Gluenz , Gerald F Späth , Najma Rachidi
BioMed Research International , 2017, 2017, pp.4635605. ⟨10.1155/2017/4635605⟩
Journal articles pasteur-01974292v1
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In vitro identification of imidazo[1,2-a]pyrazine-based antileishmanial agents and evaluation of L. major casein kinase 1 inhibition

Marc-Antoine Bazin , Sandrine Cojean , Fabrice Pagniez , Guillaume Bernadat , Christian Cavé , et al.
European Journal of Medicinal Chemistry, 2021, 210, pp.112956. ⟨10.1016/j.ejmech.2020.112956⟩
Journal articles pasteur-03108849v1