Search - Archive ouverte HAL Access content directly

Filter your results

24 Results

Caspase-8 deficiency induces a switch from TLR3 induced apoptosis to lysosomal cell death in neuroblastoma

Marie-Anaïs Locquet , Gabriel Ichim , Joseph Bisaccia , Aurelie Dutour , Serge Lebecque et al.
Scientific Reports, 2021, 11 (1), pp.10609. ⟨10.1038/s41598-021-89793-1⟩
Journal articles hal-03625041v1

Apoptosis – Fueling the oncogenic fire

Camila Castillo Ferrer , Kevin Berthenet , Gabriel Ichim
FEBS Journal, 2021, 288 (15), pp.4445-4463. ⟨10.1111/febs.15624⟩
Journal articles hal-03624981v1
Image document

Neurotrophin-3 production promotes human neuroblastoma cell survival by inhibiting TrkC-induced apoptosis.

Jimena Bouzas-Rodriguez , Jorge Ruben Cabrera , Céline Delloye-Bourgeois , Gabriel Ichim , Jean-Guy Delcros et al.
Journal of Clinical Investigation, 2010, 120 (3), pp.850-8. ⟨10.1172/JCI41013⟩
Journal articles hal-00475272v1

Increased apoptotic sensitivity of glioblastoma enables therapeutic targeting by BH3-mimetics

Anna Koessinger , Catherine Cloix , Dominik Koessinger , Dieter Henrik Heiland , Florian Bock et al.
Cell Death and Differentiation, 2022, 29 (10), pp.2089-2104. ⟨10.1038/s41418-022-01001-3⟩
Journal articles hal-03863787v1

Spontaneous activity of the mitochondrial apoptosis pathway drives chromosomal defects, the appearance of micronuclei and cancer metastasis through the Caspase-Activated DNAse

Aladin Haimovici , Christoph Höfer , Mohamed Tarek Badr , Elham Bavafaye Haghighi , Tarek Amer et al.
Cell Death and Disease, 2022, 13 (4), pp.315. ⟨10.1038/s41419-022-04768-y⟩
Journal articles hal-03667748v1
Image document

Hey1- and p53-dependent TrkC proapoptotic activity controls neuroblastoma growth

Marie Ménard , Clélia Costechareyre , Gabriel Ichim , Jonathan Blachier , David Neves et al.
PLoS Biology, 2018, 16 (5), pp.e2002912. ⟨10.1371/journal.pbio.2002912⟩
Journal articles inserm-02137893v1
Image document

Blockade of Platelet CysLT1R Receptor with Zafirlukast Counteracts Platelet Protumoral Action and Prevents Breast Cancer Metastasis to Bone and Lung

Lou Saier , Johnny Ribeiro , Thomas Daunizeau , Audrey Houssin , Gabriel Ichim et al.
International Journal of Molecular Sciences, 2022, 23 (20), pp.12221. ⟨10.3390/ijms232012221⟩
Journal articles inserm-03847792v1
Image document

TAT-RasGAP 317-326 kills cells by targeting inner-leaflet–enriched phospholipids

Marc Serulla , Gabriel Ichim , Filip Stojceski , Gianvito Grasso , Sergii Afonin et al.
Proceedings of the National Academy of Sciences of the United States of America, 2020, 117 (50), pp.31871-31881. ⟨10.1073/pnas.2014108117⟩
Journal articles hal-03415318v1

Confined migration promotes cancer metastasis through resistance to anoikis and increased invasiveness

Deborah Fanfone , Zhichong Wu , Jade Mammi , Kevin Berthenet , David Neves et al.
eLife, 2022, 11, ⟨10.7554/eLife.73150⟩
Journal articles hal-03612321v1
Image document

CDYL2 Epigenetically Regulates MIR124 to Control NF-kB/STAT3-Dependent Breast Cancer Cell Plasticity

Maha Siouda , Audrey D Dujardin , Laetitia Barbollat-Boutrand , Marco Mendoza-Parra , Benjamin Gibert et al.
iScience, 2020, 23 (6), pp.101141. ⟨10.1016/j.isci.2020.101141⟩
Journal articles hal-02956108v1
Image document

Widespread mitochondrial depletion via mitophagy does not compromise necroptosis.

Stephen w.G. Tait , Andrew Oberst , Giovanni Quarato , Sandra Milasta , Martina Haller et al.
Cell Reports, 2013, 5 (4), pp.438-41. ⟨10.1016/j.celrep.2013.10.034⟩
Journal articles pasteur-01384556v1

Neurotrophins and cell death

Gabriel Ichim , Servane Tauszig-Delamasure , Patrick Mehlen
Experimental Cell Research, 2012, 318 (11), pp.1221-1228. ⟨10.1016/j.yexcr.2012.03.006⟩
Journal articles hal-02360903v1
Image document

Live-cell imaging and mathematical analysis of the “community effect” in apoptosis

Diane Coursier , David Coulette , Hélène Leman , Emmanuel Grenier , Gabriel Ichim et al.
2022
Preprints, Working Papers, ... hal-03821641v1

Blocking SHH/Patched Interaction Triggers Tumor Growth Inhibition through Patched-Induced Apoptosis

Pierre-Antoine Bissey , Pauline Mathot , Catherine Guix , Mélissa Jasmin , Isabelle Goddard et al.
Cancer Research, 2020, 80 (10), pp.1970-1980. ⟨10.1158/0008-5472.CAN-19-1340⟩
Journal articles hal-03102147v1
Image document

Le récepteur à dépendance TRKC : mécanismes moléculaires et implications dans la tumorigénèse

Gabriel Ichim
Agricultural sciences. Université Claude Bernard - Lyon I, 2012. English. ⟨NNT : 2012LYO10317⟩
Theses tel-00936196v1
Image document

Failed Apoptosis Enhances Melanoma Cancer Cell Aggressiveness

Kevin Berthenet , Camila Castillo Ferrer , Deborah Fanfone , Nikolay Popgeorgiev , David Neves et al.
Cell Reports, 2020, 31 (10), pp.107731. ⟨10.1016/j.celrep.2020.107731⟩
Journal articles hal-02999426v1
Image document

In Cellulo Evaluation of the Therapeutic Potential of NHC Platinum Compounds in Metastatic Cutaneous Melanoma

Elsa Charignon , Mathilde Bouché , Caroline Clave-Darcissac , Georges Dahm , Gabriel Ichim et al.
International Journal of Molecular Sciences, 2020, 21 (21), pp.7826. ⟨10.3390/ijms21217826⟩
Journal articles hal-03011335v1

Low biological fluctuation of mitochondrial CpG and non-CpG methylation at the single-molecule level

Chloe Goldsmith , Jesús Rafael Rodríguez-Aguilera , Ines El-Rifai , Adrien Jarretier-Yuste , Valérie Hervieu et al.
Scientific Reports, 2021, 11 (1), pp.8032. ⟨10.1038/s41598-021-87457-8⟩
Journal articles hal-03625031v1

Sometimes even apoptosis fails: implications for cancer

Kevin Berthenet , Kathrin Weber , Gabriel Ichim
Molecular & Cellular Oncology, 2020, 7 (6), pp.1797430. ⟨10.1080/23723556.2020.1797430⟩
Journal articles hal-03624990v1

Mitochondrial dynamics regulate genome stability via control of caspase-dependent DNA damage

Kai Cao , Joel Riley , Rosalie Heilig , Alfredo Montes-Gómez , Esmee Vringer et al.
Developmental Cell, 2022, ⟨10.1016/j.devcel.2022.03.019⟩
Journal articles hal-03667751v1

The Dependence Receptor TrkC Triggers Mitochondria-Dependent Apoptosis upon Cobra-1 Recruitment

Gabriel Ichim , Anne-Laure Genevois , Marie Ménard , Li-Ying Yu , Juliana m. Coelho-Aguiar et al.
Molecular Cell, 2013, 51 (5), pp.632-646. ⟨10.1016/j.molcel.2013.08.021⟩
Journal articles hal-02360899v1

Profiling Anti-Apoptotic BCL-xL Protein Expression in Glioblastoma Tumorspheres

Deborah Fanfone , Ahmed Idbaih , Jade Mammi , Mathieu Gabut , Gabriel Ichim et al.
Cancers, 2020, 12 (10), pp.2853. ⟨10.3390/cancers12102853⟩
Journal articles hal-03613078v1

Blockade of Platelet CysLT1R Receptor with Zafirlukast Counteracts Platelet Protumoral Action and Prevents Breast Cancer Metastasis to Bone and Lung

Lou Saier , Johnny Ribeiro , Thomas Daunizeau , Audrey Houssin , Gabriel Ichim et al.
International Journal of Molecular Sciences, 2022, 23 (20), pp.12221. ⟨10.3390/ijms232012221⟩
Journal articles hal-03863771v1
Image document

Keeping Cell Death Alive: An Introduction into the French Cell Death Research Network

Gabriel Ichim , Benjamin Gibert , Sahil Adriouch , Catherine Brenner , Nathalie Davoust et al.
Biomolecules, 2022, 12 (7), pp.901. ⟨10.3390/biom12070901⟩
Journal articles hal-03711790v1