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Plasmodium falciparum: multifaceted resistance to artemisinins

Lucie Paloque , Arba Pramundita Ramadani , Odile Mercereau-Puijalon , Jean-Michel Augereau , Françoise Benoit-Vical et al.
Malaria Journal, 2016, 15 (1), pp.149/1-12. ⟨10.1186/s12936-016-1206-9⟩
Journal articles inserm-01322524v1
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Design, Synthesis and Efficacy of Hybrid Triclosan‐gold Based Molecules on Artemisinin‐resistant Plasmodium falciparum and Leishmania infantum Parasites

Manel Ouji , Sandra Bourgeade-Delmas , Álvaro Fernández Álvarez , Jean-Michel Augereau , Alexis Valentin et al.
ChemistrySelect, 2020, 5 (2), pp.619-625. ⟨10.1002/slct.201904345⟩
Journal articles hal-02445188v1

Superoxide

Chinedu Egwu , Ioannis Tsamesidis , Pierre Pério , Jean-Michel Augereau , Françoise Benoit-Vical et al.
Free Radical Biology and Medicine, 2021, 167, pp.271-275. ⟨10.1016/j.freeradbiomed.2021.03.001⟩
Journal articles hal-03203905v1

Samvisterin, a new natural antiplasmodial betulin derivative from Uapaca paludosa (Euphorbiaceae)

J. T. Banzouzi , P. Njomnang Soh , S. Ramos , P. Toto , A. Cave et al.
Journal of Ethnopharmacology, 2015, 173, pp.100-104. ⟨10.1016/j.jep.2015.07.023⟩
Journal articles hal-01925141v1

Multiple phenotypic and genotypic artemisinin sensitivity evaluation of Malian Plasmodium falciparum isolates

Karamoko Niare , Lucie Paloque , Sandie Ménard , Pety Tor , Arba Pramundita Ramadani et al.
American Journal of Tropical Medicine and Hygiene, 2018, 98 (4), pp.1123-1131. ⟨10.4269/ajtmh.17-0798⟩
Journal articles hal-01963527v1
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Do ethnobotanical and laboratory data predict clinical safety and efficacy of anti-malarial plants?

Merlin Willcox , Françoise Benoit-Vical , Dennis Fowler , Geneviève Bourdy , Gemma Burford et al.
Malaria Journal, 2011, 10 Suppl 1, pp.S7. ⟨10.1186/1475-2875-10-S1-S7⟩
Journal articles pasteur-00836690v1
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Hybrid Gold(I) NHC-Artemether Complexes to Target Falciparum Malaria Parasites

Manel Ouji , Guillaume Barnoin , Alvaro Fernandez Alvarez , Jean-Michel Augereau , Catherine Hemmert et al.
Molecules, 2020, 25 (12), pp.2817. ⟨10.3390/molecules25122817⟩
Journal articles hal-02883402v1

In vivo efficacy and parasite clearance of artesunate plus sulfadoxine-pyrimethamine versus artemether-lumefantrine in Mali

Karamoko Niare , Antoine Dara , Issaka Sagara , Mahamadou S. Sissoko , Cheick Oumar Guindo et al.
American Journal of Tropical Medicine and Hygiene, 2016, 94 (3), pp.634-639. ⟨10.4269/ajtmh.15-0503⟩
Journal articles hal-01937590v1

K13-propeller mutations confer artemisinin resistance in Plasmodium falciparum clinical isolates

Judith Straimer , Nina F. Gnadig , Benoit Witkowski , Chanaki Amaratunga , Valentine Duru et al.
Science, 2015, 347 (6220), pp.428-431. ⟨10.1126/science.1260867⟩
Journal articles hal-01925134v1

Molecular surveillance of Plasmodium falciparum resistance to artemisinin-based combination therapies in the Democratic Republic of Congo

Dieudonneé Makaba Mvumbi , Thierry Lengu Bobanga , Jean-Marie Ntumba Kayembe , Georges Lelo Mvumbi , Hippolyte Nani-Tuma Situakibanza et al.
PLoS ONE, 2017, 12 (6), pp.e0179142. ⟨10.1371/journal.pone.0179142⟩
Journal articles hal-01947825v1
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Mutation in the Plasmodium falciparum BTB/POZ Domain of K13 Protein Confers Artemisinin Resistance

Lucie Paloque , Romain Coppée , Barbara Stokes , Nina Gnädig , Karamoko Niaré et al.
Antimicrobial Agents and Chemotherapy, 2022, 66 (1), pp.e01320-21. ⟨10.1128/AAC.01320-21⟩
Journal articles hal-03561782v1

Cogniauxia podolaena: bioassay-guided fractionation of defoliated stems, isolation of active compounds, antiplasmodial activity and cytotoxicity.

Jean Théophile Banzouzi , Patrice Njomnang Soh , Bernard Mbatchi , Adrien Cavé , Suzanne Ramos et al.
Planta Medica, 2008, 74 (12), pp.1453-6. ⟨10.1055/s-2008-1081341⟩
Journal articles hal-00345168v1

Plasmodium falciparum resistance to artemisinin-based combination therapies (ACTs): Fears of widespread drug resistance

Françoise Benoit-Vical , Lucie Paloque , Jean-Michel Augereau
Bulletin de l'Académie Nationale de Médecine, 2016, 200 (3), pp.477-489
Journal articles hal-01937598v1
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Identification of compounds active against quiescent artemisinin-resistant Plasmodium falciparum parasites via the quiescent-stage survival assay (QSA)

Thibaud Reyser , Lucie Paloque , Manel Ouji , Michel Nguyen , Sandie Ménard et al.
Journal of Antimicrobial Chemotherapy, 2020, 75 (10), pp.2826-2834. ⟨10.1093/jac/dkaa250⟩
Journal articles hal-02948398v1
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Ex vivo activity of the ACT new components pyronaridine and piperaquine in comparison with conventional ACT drugs against isolates of Plasmodium falciparum.

Aurélie Pascual , Philippe Parola , Françoise Benoit-Vical , Fabrice Simon , Denis Malvy et al.
Malaria Journal, 2012, 11, pp.45. ⟨10.1186/1475-2875-11-45⟩
Journal articles pasteur-00836167v1
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Novel molecule combinations and corresponding hybrids targeting artemisinin-resistant Plasmodium falciparum parasites

Manel Ouji , Michel Nguyen , Romain Mustière , Tony Jimenez , Jean-Michel Augereau et al.
Bioorganic & Medicinal Chemistry Letters, 2021, 39, pp.127884. ⟨10.1016/j.bmcl.2021.127884⟩
Journal articles hal-03170976v1

Induction of multidrug tolerance in plasmodium falciparum by extended artemisinin pressure

Sandie Ménard , Tanila Ben Haddou , Arba Pramundita Ramadani , F. Ariey , Xavier Iriart et al.
Emerging Infectious Diseases, 2015, 21 (10), pp.1733-1741. ⟨10.3201/eid2110.150682⟩
Journal articles hal-01925135v1

Pyranocoumarin and Triterpene from Millettia richardiana.

M. Rajemiarimiraho , J. T. Banzouzi , S. R. Rakotonandrasana , P. Chalard , Françoise Benoit-Vical et al.
Natural Product Communications , 2013, 8, pp.1099-1100
Journal articles hal-00950546v1

In vitro and in vivo properties of ellagic acid in malaria treatment.

Patrice Njomnang Soh , Benoît Witkowski , David Olagnier , Marie-Laure Nicolau , Maria-Concepcion Garcia-Alvarez et al.
Antimicrobial Agents and Chemotherapy, 2009, 53 (3), pp.1100-6. ⟨10.1128/AAC.01175-08⟩
Journal articles hal-00522424v1

Endoperoxide-based compounds: cross-resistance with artemisinins and selection of a Plasmodium falciparum lineage with a K13 non-synonymous polymorphism

Lucie Paloque , Benoit Witkowski , Joël Lelièvre , Manel Ouji , Tanila Ben Haddou et al.
Journal of Antimicrobial Chemotherapy, 2018, 73 (2), pp.395-403. ⟨10.1093/jac/dkx412⟩
Journal articles hal-01963522v1

Effects of Antimalarial Molecules on the Gametocyte Stage of Plasmodium falciparum : The Debate

Odile Dechy-Cabaret , Françoise Benoit-Vical
Journal of Medicinal Chemistry, 2012, 55 (23), pp.10328-10344. ⟨10.1021/jm3005898⟩
Journal articles hal-02909739v1

Synthesis, structures, and antimalarial activities of some silver(I), gold(I) and gold(III) complexes involving N-heterocyclic carbene ligands

Catherine Hemmert , Aymeric Fabié , Aude Fabre , Françoise Benoit-Vical , Heinz Gornitzka et al.
European Journal of Medicinal Chemistry, 2013, 60, pp.64-75. ⟨10.1016/j.ejmech.2012.11.038⟩
Journal articles hal-02907994v1

Antiprotozoal activities of Millettia richardiana (Fabaceae) from Madagascar.

Manitriniaina Rajemiarimiraho , Jean-Théophile Banzouzi , Marie-Laure Nicolau-Travers , Suzanne Ramos , Zakaria Cheikh-Ali et al.
Molecules, 2014, 19 (4), pp.4200-4211. ⟨10.3390/molecules19044200⟩
Journal articles hal-01011996v1

Influence of amodiaquine on the antimalarial activity of ellagic acid: Crystallographic and biological studies

E. Zeslawska , B. Oleksyn , Aude Fabre , Françoise Benoit-Vical
Chemical Biology & Drug Design, 2014, 84 (6), pp.669-675. ⟨10.1111/cbdd.12359⟩
Journal articles istex hal-02023181v1

SAYE: The story of an antimalarial phytomedicine from Burkina Faso

Zéphirin Dakuyo , Aline Lamien Meda , Da Ollo , Martin Kiendrebeogo , Maminata Traore-Coulibaly et al.
Journal of Alternative and Complementary Medicine, 2015, 21 (4), pp.187-195. ⟨10.1089/acm.2014.0147⟩
Journal articles hal-01925136v1
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Molecular monitoring of plasmodium falciparum drug susceptibility at the time of the introduction of artemisinin-based combination therapy in Yaoundé, Cameroon

Sandie Ménard , Isabelle Morlais , Rachida Tahar , Collins Sayang , Pembe Mayengue et al.
Malaria Journal, 2012, 11 (1), pp.113. ⟨10.1186/1475-2875-11-113⟩
Journal articles ird-02896995v1
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Concentration and purification by magnetic separation of the erythrocytic stages of all human Plasmodium species

Clotilde Ribaut , Antoine Berry , Severine Chevalley , Karine Reybier , Isabelle Morlais et al.
Malaria Journal, 2008, 7 (1), pp.45. ⟨10.1186/1475-2875-7-45⟩
Journal articles ird-02896998v1
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Alkoxyamines Designed as Potential Drugs against Plasmodium and Schistosoma Parasites

Thibaud Reyser , Tung H To , Chinedu Egwu , Lucie Paloque , Michel Nguyen et al.
Molecules, 2020, 25 (17), pp.3838. ⟨10.3390/molecules25173838⟩
Journal articles hal-02948878v1
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In Vitro and In Silico Antimalarial Evaluation of FM-AZ, a New Artemisinin Derivative

Ioannis Tsamesidis , Farnoush Mousavizadeh , Chinedu Egwu , Dionysia Amanatidou , Antonella Pantaleo et al.
Medicines, 2022, 9 (2), pp.8. ⟨10.3390/medicines9020008⟩
Journal articles hal-03660647v1
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Antiplasmodial activities of gold(I) complexes involving functionalized N-heterocyclic carbenes

Catherine Hemmert , Arba Pramundita Ramadani , Luca Boselli , Alvaro Fernandez Alvarez , Lucie Paloque et al.
Bioorganic and Medicinal Chemistry, 2016, 24 (13), pp.3075-3082. ⟨10.1016/j.bmc.2016.05.023⟩
Journal articles hal-01937596v1