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The Trimerization Domain of Nemo Is Composed of the Interacting C-terminal CC2 and LZ Coiled-coil Subdomains

Fabrice Agou , François Traincard , Emilie Vinolo , Gilles Courtois , Shoji Yamaoka , et al.
Journal of Biological Chemistry, 2004, 279 (27), pp.27861-27869. ⟨10.1074/jbc.M314278200⟩
Journal articles pasteur-03276984v1

Obtention de mutants de la protéine NEMO par mutagenèse dirigée afin de valider la structure au rayon X et obtention de peptides inhibiteurs de l'activation de la voie NF-kB

Fabrice Agou , Jeanne Chiaravalli , Stephane Duquerroy , Elisabeth Fontan , Olivera Grubisha , et al.
Patent n° : 0900127. 2009
Patents hal-00512131v1
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A highly sensitive cell-based luciferase assay for high-throughput automated screening of SARS-CoV-2 nsp5/3CLpro inhibitors

K.Y. Chen , T. Krischuns , L. Ortega Varga , E. Harigua-Souiai , S. Paisant , et al.
Antiviral Research, 2022, 201, pp.105272. ⟨10.1016/j.antiviral.2022.105272⟩
Journal articles pasteur-03840856v1

IκB kinase overcomes PI3K/Akt and ERK/MAPK to control FOXO3a activity in acute myeloid leukemia

Nicolas Chapuis , Sophie Park , Laurent Leotoing , Jerome Tamburini , Frederique Verdier , et al.
Blood, 2010, 116 (20), pp.4240-4250. ⟨10.1182/blood-2009-12-260711⟩
Journal articles pasteur-03277054v1

Neuraminidase of 2007–2008 influenza A(H1N1) viruses shows increased affinity for sialic acids due to the D344N substitution

Marie-Anne Rameix-Welti , Sandie Munier , Sebastien Le Gal , Frederique Cuvelier , Fabrice Agou , et al.
Antiviral Therapy, 2011, 16 (4), pp.597-603. ⟨10.3851/IMP1804⟩
Journal articles pasteur-03277069v1

Inhibition of NF-kappa B activation by peptides targeting NF-kappa B essential modulator (nemo) oligomerization.

Fabrice Agou , Gilles Courtois , Jeanne Chiaravalli , Françoise Baleux , Yves-Marie Coïc , et al.
Journal of Biological Chemistry, 2004, 279 (52), pp.54248-57. ⟨10.1074/jbc.M406423200⟩
Journal articles pasteur-00166822v1

Inhibition of NEMO, the regulatory subunit of the IKK complex, induces apoptosis in high-risk myelodysplastic syndrome and acute myeloid leukemia.

G. Carvalho , C. Fabre , T. Braun , J. Grosjean , L. Ades , et al.
Oncogene, 2006, 26 (16), pp.2299-307. ⟨10.1038/sj.onc.1210043⟩
Journal articles pasteur-00162838v1

Lack of interaction between NEMO and SHARPIN impairs linear ubiquitination and NF-κB activation and leads to incontinentia pigmenti.

Elodie Bal , Emmanuel Laplantine , Yamina Hamel , Virginie Dubosclard , Bertrand Boisson , et al.
Journal of Allergy and Clinical Immunology, 2017, 17 (4), ⟨10.1016/j.jaci.2016.11.056⟩
Journal articles hal-01560363v1
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A novel screening strategy to identify histone methyltransferase inhibitors reveals a crosstalk between DOT1L and CARM1

Yang Si , Corentin Bon , Magdalena Barbachowska , Veronique Cadet-Daniel , Corinne Jallet , et al.
RSC Chemical Biology, 2022, 3 (4), pp.456-467. ⟨10.1039/d1cb00095k⟩
Journal articles pasteur-03693863v1

NEMO specifically recognizes K63-linked poly-ubiquitin chains through a new bipartite ubiquitin-binding domain

E Laplantine , Elisabeth Fontan , J Chiaravalli , T Lopez , G Lakisic , et al.
EMBO Journal, 2009, 28 (19), pp.2885-2895. ⟨10.1038/emboj.2009.241⟩
Journal articles pasteur-03277047v1

Immunodeficiency, autoinflammation and amylopectinosis in humans with inherited HOIL-1 and LUBAC deficiency

Bertrand Boisson , Emmanuel Laplantine , Carolina Prando , Silvia Giliani , Elisabeth Israelsson , et al.
Nature Immunology, 2012, 13 (12), pp.1178-1186. ⟨10.1038/ni.2457⟩
Journal articles pasteur-03277102v1

In Vivo Protein Cross-Linking

Fabrice Agou , Michel Véron
Protein-Protein Interactions. Methods in Molecular Biology, vol 1278, 1278, Humana Press, pp.391-405, 2015, 978-1-4939-2425-7. ⟨10.1007/978-1-4939-2425-7_26⟩
Book sections pasteur-03277116v1
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Expression of Rat Aspartyl-tRNA Synthetase in Saccharomyces cerevisiae

Fabrice Agou , Jean-Pierre Waller , Marc Mirande
Journal of Biological Chemistry, 1996, 271 (46), pp.29295-29303. ⟨10.1074/jbc.271.46.29295⟩
Journal articles hal-03276099v1

Complementation Cloning of NEMO, a Component of the IκB Kinase Complex Essential for NF-κB Activation

Shoji Yamaoka , Gilles Courtois , Christine Bessia , Simon T. Whiteside , Robert Weil , et al.
Cell, 1998, 93 (7), pp.1231-1240. ⟨10.1016/s0092-8674(00)81466-x⟩
Journal articles pasteur-03276765v1
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A sensitive fluorescence-based assay to monitor enzymatic activity of the essential integral membrane protein Apolipoprotein N-acyltransferase (Lnt)

Karine Nozeret , Alix Boucharlat , Fabrice Agou , Nienke Buddelmeijer
Scientific Reports, 2019, 9 (1), pp.15978. ⟨10.1038/s41598-019-52106-8⟩
Journal articles pasteur-02421050v1

Identification of a new NEMO/TRAF6 interface affected in incontinentia pigmenti pathology

Jérémie Gautheron , Alessandra Pescatore , Francesca Fusco , Elio Esposito , Shoji Yamaoka , et al.
Human Molecular Genetics, 2010, 19 (16), pp.3138-3149. ⟨10.1093/hmg/ddq222⟩
Journal articles pasteur-03277064v1

Inhibition pharmacologique de la voie de signalisation NF-kB

Gilles Courtois , Fabrice Agou , Laurence Michel
Hématologie, 2006, 12 (1), pp.50-60
Journal articles pasteur-03277163v1

Aspartyl-tRNA synthetase from rat: in vitro functional analysis of its assembly into the multisynthetase complex

Fabrice Agou , M. Mirande
European Journal of Biochemistry, 1997, 243 (1-2), pp.259-267. ⟨10.1111/j.1432-1033.1997.0259a.x⟩
Journal articles pasteur-03276719v1

NEMO Trimerizes through Its Coiled-coil C-terminal Domain

Fabrice Agou , Fei Ye , Stéphane Goffinont , Gilles Courtois , Shoji Yamaoka , et al.
Journal of Biological Chemistry, 2002, 277 (20), pp.17464-17475. ⟨10.1074/jbc.M201964200⟩
Journal articles hal-02112165v1
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Interrogating RNA and protein spatial subcellular distribution in smFISH data with DypFISH

Anca Savulescu , Robyn Brackin , Emmanuel Bouilhol , Benjamin Dartigues , Jonathan Warrell , et al.
Cell Reports Methods, 2021, 1 (5), pp.100068. ⟨10.1016/j.crmeth.2021.100068⟩
Journal articles hal-03349483v1
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High-Content RNAi Phenotypic Screening Unveils the Involvement of Human Ubiquitin-Related Enzymes in Late Cytokinesis

Mikaël Boullé , Laurianne Davignon , Keïs Nabhane Saïd Halidi , Salomé Guez , Emilie Giraud , et al.
Cells, 2022, 11 (23), pp.3862. ⟨10.3390/cells11233862⟩
Journal articles pasteur-04104805v1
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Super-resolution microscopy reveals a preformed NEMO lattice structure that is collapsed in incontinentia pigmenti

Janine Scholefield , Ricardo Henriques , Anca Savulescu , Elisabeth Fontan , Alix F Boucharlat , et al.
Nature Communications, 2016, 7, pp.12629. ⟨10.1038/ncomms12629⟩
Journal articles pasteur-01377851v1

Design and synthesis of naturally-inspired SARS-CoV-2 inhibitors

Haitham Hassan , Jeanne Chiavaralli , Afnan Hassan , Loay Bedda , Tim Krischuns , et al.
RSC Medicinal Chemistry, 2023, 14 (3), pp.507-519. ⟨10.1039/D2MD00149G⟩
Journal articles hal-03981817v1
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Two NEMO-like Ubiquitin-Binding Domains in CEP55 Differently Regulate Cytokinesis

Keïs Nabhane Said Halidi , Elisabeth Fontan , Alix Boucharlat , Laurianne Davignon , Marine Charpentier , et al.
iScience, 2019, 20, pp.292-309. ⟨10.1016/j.isci.2019.08.042⟩
Journal articles pasteur-02319623v1

Inhibition of NF-kappaB activation with designed ankyrin-repeat proteins targeting the ubiquitin-binding/oligomerization domain of NEMO.

Emanuel Wyler , Monika Kaminska , Yves-Marie Coïc , Françoise Baleux , Michel Véron , et al.
Protein Science, 2007, 16 (9), pp.2013-22. ⟨10.1110/ps.072924907⟩
Journal articles pasteur-00187352v1
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Solution structure of NEMO zinc finger and impact of an anhidrotic ectodermal dysplasia with immunodeficiency-related point mutation.

Florence Cordier , Emilie Vinolo , Michel Véron , Muriel Delepierre , Fabrice Agou
Journal of Molecular Biology, 2008, 377 (5), pp.1419-32. ⟨10.1016/j.jmb.2008.01.048⟩
Journal articles pasteur-00366221v1
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Coupling between Catalysis and Oligomeric Structure in Nucleoside Diphosphate Kinase

Sébastien Mesnildrey , Fabrice Agou , Anna Karlsson , Dominique Deville Bonne , Michel Véron
Journal of Biological Chemistry, 1998, 273 (8), pp.4436-4442. ⟨10.1074/jbc.273.8.4436⟩
Journal articles pasteur-03276730v1
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Single Strand DNA Specificity Analysis of Human Nucleoside Diphosphate Kinase B

Fabrice Agou , Sharona Raveh , Sébastien Mesnildrey , Michel Véron
Journal of Biological Chemistry, 1999, 274 (28), pp.19630-19638. ⟨10.1074/jbc.274.28.19630⟩
Journal articles pasteur-03276872v1

NEMO oligomerization in the dynamic assembly of the IκB kinase core complex

Elisabeth Fontan , François Traincard , Samuel G. Levy , Shoji Yamaoka , Michel Véron , et al.
FEBS Journal, 2007, 274 (10), pp.2540-2551. ⟨10.1111/j.1742-4658.2007.05788.x⟩
Journal articles pasteur-03276989v1
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Characterising proteolysis during SARS-CoV-2 infection identifies viral cleavage sites and cellular targets with therapeutic potential

Bjoern Meyer , Jeanne Chiaravalli , Stacy Gellenoncourt , Philip Brownridge , Dominic Bryne , et al.
Nature Communications, 2021, 12 (1), pp.5553. ⟨10.1038/s41467-021-25796-w⟩
Journal articles pasteur-03654295v1