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Exploring the genetic basis of human population differences in DNA methylation and their causal impact on immune gene regulation

Lucas T Husquin , Maxime Rotival , Maud Fagny , Hélène Quach , Nora Zidane , et al.
Genome Biology, 2018, 19, pp.222. ⟨10.1186/s13059-018-1601-3⟩
Journal articles hal-02352909v1
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IRF4 haploinsufficiency in a family with Whipple's disease

Antoine Guerin , Gaspard Kerner , Nico Marr , Janet G. Markle , Florence Fenollar , et al.
eLife, 2018, 7, pp.e32340. ⟨10.7554/eLife.32340⟩
Journal articles hal-01789213v1
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The human CIB1–EVER1–EVER2 complex governs keratinocyte-intrinsic immunity to β-papillomaviruses

Sarah Jill de Jong , Amandine Créquer , Irina Matos , David Hum , Vignesh Gunasekaran , et al.
Journal of Experimental Medicine, 2018, 215 (9), pp.2289-2310. ⟨10.1084/jem.20170308⟩
Journal articles hal-02352844v1

Sub-Saharan African coding sequence variation and haplotype diversity at theNAT2gene

Etienne Patin , Christine Harmant , Ken Kidd , Judith Kidd , Alain Froment , et al.
Human Mutation, 2006, 27 (7), pp.720 - 720. ⟨10.1002/humu.9438⟩
Journal articles pasteur-03682093v1
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A genome-wide Approximate Bayesian Computation approach suggests only limited numbers of soft sweeps in humans over the last 100,000 years

Guillaume Laval , Etienne Patin , Pierre Boutillier , Lluis Quintana-Murci
2020
Preprints, Working Papers, ... pasteur-02882154v1

The Genomic Impact of European Colonization of the Americas.

Linda Ongaro , Marilia Scliar , Rodrigo Flores , Alessandro Raveane , Davide Marnetto , et al.
Current Biology - CB, 2019, 29 (23), pp.3974-3986.e4. ⟨10.1016/j.cub.2019.09.076⟩
Journal articles hal-03020436v1
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Associations between untargeted plasma metabolomic signatures and gut microbiota composition in the Milieu Intérieur population of healthy adults

Valentin Partula , Mélanie Deschasaux-Tanguy , Stanislas Mondot , Agnès Victor-Bala , Nadia Bouchemal , et al.
British Journal of Nutrition, 2021, 126 (7), pp. 982-992. ⟨10.1017/S0007114520004870⟩
Journal articles hal-03073792v1
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Genomic insights into population history and biological adaptation in Oceania

Jeremy Choin , Javier Mendoza-Revilla , Lara R Arauna , Sebastian Cuadros-Espinoza , Olivier Cassar , et al.
Nature, 2021, 592 (7855), pp.583-589. ⟨10.1038/s41586-021-03236-5⟩
Journal articles pasteur-03205291v1
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Genome-wide data from the Bubi of Bioko Island clarifies the Atlantic fringe of the Bantu dispersal

Pere Gelabert , Manuel Ferrando-Bernal , Toni De-Dios , Benedetta Mattorre , Elena Campoy , et al.
BMC Genomics, 2019, 20 (1), pp.179. ⟨10.1186/s12864-019-5529-0⟩
Journal articles hal-02353006v1
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Two common disease-associated TYK2 variants impact exon splicing and TYK2 dosage

Zhi Li , Maxime Rotival , Etienne Patin , Frédérique Michel , Sandra Pellegrini
PLoS ONE, 2020, 15 (1), pp.e0225289. ⟨10.1371/journal.pone.0225289⟩
Journal articles pasteur-02468251v1

Dispersals and genetic adaptation of Bantu-speaking populations in Africa and North America.

Etienne Patin , Marie Lopez , Rebecca Grollemund , Paul Verdu , Christine Harmant , et al.
Science, 2017, 356 (6337), pp.543-546. ⟨10.1126/science.aal1988⟩
Journal articles hal-02277558v1
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Evolutionary genetics evidence of an essential, non-redundant role of the IFN-γ pathway in protective immunity

Jeremy Manry , Guillaume Laval , Etienne Patin , Simona Fornarino , Christiane Bouchier , et al.
Human Mutation, 2011, 32 (6), pp.633-42. ⟨10.1002/humu.21484⟩
Journal articles istex hal-00627541v1
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Population genetic diversity of the NAT2 gene supports a role of acetylation in human adaptation to farming in Central Asia.

Hélène Magalon , Etienne Patin , Frédéric Austerlitz , Tatyana Hegay , Almaz Aldashev , et al.
European Journal of Human Genetics, 2008, 16 (2), pp.243-51. ⟨10.1038/sj.ejhg.5201963⟩
Journal articles hal-00271644v1
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Gut microbiome stability and dynamics in healthy donors and patients with non-gastrointestinal cancers

Allyson L. Byrd , Menghan Liu , Kei E. Fujimura , Svetlana Lyalina , Deepti R. Nagarkar , et al.
Journal of Experimental Medicine, 2020, 218 (1), ⟨10.1084/jem.20200606⟩
Journal articles pasteur-03036477v1

Tuberculosis and impaired IL-23–dependent IFN-γ immunity in humans homozygous for a common TYK2 missense variant.

Stéphanie Boisson-Dupuis , Noe Ramirez-Alejo , Zhi Li , Etienne Patin , Geetha Rao , et al.
Science Immunology, 2018, 3 (30), pp.eaau8714. ⟨10.1126/sciimmunol.aau8714⟩
Journal articles pasteur-02070591v1

A Y-chromosome portrait of Jerban population (Tunisia) to elucidate its complex demographic history

Franz Manni , P. Leonardi , Etienne Patin , H. Khojet El Khil , K. Skorecki , et al.
Bulletins et Mémoires de la Société d'anthropologie de Paris, 2006, 17 (1-2), pp.103-114. ⟨10.4000/bmsap.956⟩
Journal articles hal-00263455v1

Genome-Wide Association Study Identifies Variants Associated With Progression of Liver Fibrosis From HCV Infection

Etienne Patin , Zoltán Kutalik , Julien Guergnon , Stéphanie Bibert , Bertrand Nalpas , et al.
Gastroenterology, 2012, 143 (5), pp.1244-1252.e12. ⟨10.1053/j.gastro.2012.07.097⟩
Journal articles hal-02353071v1
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Inferring the demographic history of African farmers and pygmy hunter-gatherers using a multilocus resequencing data set.

Etienne Patin , Guillaume Laval , Luis B. Barreiro , Antonio Salas , Ornella Semino , et al.
PLoS Genetics, 2009, 5 (4), pp.e1000448. ⟨10.1371/journal.pgen.1000448⟩
Journal articles hal-00397240v1

Human IFN-γ immunity to mycobacteria is governed by both IL-12 and IL-23

Ruben Martinez-Barricarte , Janet Markle , Cindy Ma , Elissa K Deenick , Noe Ramirez-Alejo , et al.
Science Immunology, 2018, 3 (30), pp.eaau6759. ⟨10.1126/sciimmunol.aau6759⟩
Journal articles hal-02352927v1
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Integrative genetic and immune cell analysis of plasma proteins in healthy donors identifies novel associations involving primary immune deficiency genes

Barthelemy Caron , Etienne Patin , Maxime Rotival , Bruno Charbit , Matthew L Albert , et al.
2021
Preprints, Working Papers, ... pasteur-03244404v1

Natural selection has driven population differentiation in modern humans

Luis B. Barreiro , Guillaume Laval , Hélène Quach , Etienne Patin , Lluis Quintana-Murci
Nature Genetics, 2008, 40 (3), pp.340-345. ⟨10.1038/ng.78⟩
Journal articles hal-02352821v1
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Human ancient DNA analyses reveal the high burden of tuberculosis in Europeans over the last 2,000 years

Gaspard Kerner , Guillaume Laval , Etienne Patin , Stéphanie Boisson-Dupuis , Laurent Abel , et al.
American Journal of Human Genetics, 2021, 108 (3), pp.517 - 524. ⟨10.1016/j.ajhg.2021.02.009⟩
Journal articles pasteur-03169933v1
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Genomic Evidence for Local Adaptation of Hunter-Gatherers to the African Rainforest

Marie Lopez , Jeremy Choin , Martin Sikora , Katherine Siddle , Christine Harmant , et al.
Current Biology - CB, 2019, 29 (17), pp.2926-2935.e4. ⟨10.1016/j.cub.2019.07.013⟩
Journal articles hal-02271461v1
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Mutations involving the SRY-related gene SOX8 are associated with a spectrum of human reproductive anomalies

Marie-France Portnoi , Marie-Charlotte Dumargne , Sandra Rojo , Selma F Witchel , Andrew J Duncan , et al.
Human Molecular Genetics, 2018, 27 (7), pp.1228-1240. ⟨10.1093/hmg/ddy037⟩
Journal articles hal-02018306v1
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Environmental and genetic drivers of population differences in SARS-CoV-2 immune responses

Yann Aquino , Aurélie Bisiaux , Zhi Li , Mary O’neill , Javier Mendoza-Revilla , et al.
2023
Preprints, Working Papers, ... pasteur-03913748v1
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Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines

Milieu Intérieur Consortium , Petar Scepanovic , Cécile Alanio , Christian Hammer , Flavia Hodel , et al.
Genome Medicine, 2018, 10 (1), pp.59. ⟨10.1186/s13073-018-0568-8⟩
Journal articles pasteur-01758699v1
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Deciphering the ancient and complex evolutionary history of human arylamine N-acetyltransferase genes.

Etienne Patin , Luis B Barreiro , Pardis C Sabeti , Frédéric Austerlitz , Francesca Luca , et al.
American Journal of Human Genetics, 2006, 78 (3), pp.423-36. ⟨10.1086/500614⟩
Journal articles pasteur-00169326v1

Evolutionary insights into the high worldwide prevalence of MBL2 deficiency alleles

Paul Verdu , Luis Barreiro , Etienne Patin , Antoine Gessain , Olivier Cassar , et al.
Human Molecular Genetics, 2006, 15 (17), pp.2650-2658. ⟨10.1093/hmg/ddl193⟩
Journal articles hal-02271444v1

The demographic history and mutational load of African hunter-gatherers and farmers

Marie Lopez , Athanasios Kousathanas , Hélène Quach , Christine Harmant , Patrick Mouguiama-Daouda , et al.
Nature Ecology & Evolution, 2018, 2 (4), pp.721-730. ⟨10.1038/s41559-018-0496-4⟩
Journal articles hal-02271464v1

Human RHOH deficiency causes T cell defects and susceptibility to EV-HPV infections

Amandine Crequer , Anja Troeger , Etienne Patin , Cindy Ma , Capucine Picard , et al.
Journal of Clinical Investigation, 2012, 122 (9), pp.3239-3247. ⟨10.1172/JCI62949⟩
Journal articles hal-03691599v1