Search - Archive ouverte HAL Access content directly

Filter your results

33 Results
Image document

Lipophilic Chemicals from Diesel Exhaust Particles Trigger Calcium Response in Human Endothelial Cells via Aryl Hydrocarbon Receptor Non-Genomic Signalling

Bendik C Brinchmann , E. Le Ferrec , Normand Podechard , Dominique Lagadic-Gossmann , Kenji F Shoji et al.
International Journal of Molecular Sciences, 2018, 19 (5), pp.1429. ⟨10.3390/ijms19051429⟩
Journal articles hal-01795808v1
Image document

Benzo(a) pyrene triggers desensitization of beta 2-adrenergic pathway

Abdullah Mayati , Normand Podechard , Manuelle Rineau , Lydie Sparfel , Dominique Lagadic-Gossmann et al.
Scientific Reports, 2017, 7 (1), pp.3262. ⟨10.1038/s41598-017-03646-4⟩
Journal articles hal-01560151v1
Image document

Lipophilic components of diesel exhaust particles induce pro-inflammatory responses in human endothelial cells through AhR dependent pathway(s)

Bendik C. Brinchmann , Tonje Skuland , Mia H. Rambol , Krisztina Szoke , Jan E. Brinchmann et al.
Particle and Fibre Toxicology, 2018, 15 (1), pp.21. ⟨10.1186/s12989-018-0257-1⟩
Journal articles hal-01863051v1
Image document

Extracellular vesicles released by polycyclic aromatic hydrocarbons-treated hepatocytes trigger oxidative stress in recipient hepatocytes by delivering iron

Nettie van Meteren , Dominique Lagadic-Gossmann , Normand Podechard , Dimitri Gobart , Isabelle Gallais et al.
Free Radical Biology and Medicine, 2020, 160, pp.246-262. ⟨10.1016/j.freeradbiomed.2020.08.001⟩
Journal articles hal-02930146v1
Image document

G-protein coupled receptors (GPCR) and environmental exposure. Consequences for cell metabolism using the β-adrenoceptors as example

E. Le Ferrec , Johan Øvrevik
Current Opinion in Toxicology, 2018, 8, pp.14-19. ⟨10.1016/j.cotox.2017.11.012⟩
Journal articles hal-01699375v1
Image document

PAHs increase the production of extracellular vesicles both in vitro in endothelial cells and in vivo in urines from rats

Manon Le Goff , Dominique Lagadic-Gossmann , Remi Latour , Normand Podechard , Nathalie Grova et al.
Environmental Pollution, 2019, 255, pp.113171. ⟨10.1016/j.envpol.2019.113171⟩
Journal articles hal-02302334v1

Applications Using Caco-2 and TC7 Cells for Drug Metabolism Studies

Eric Le Ferrec , Olivier Fardel
Encyclopedia of Drug Metabolism and Interactions, John Wiley & Sons, 2011, ⟨10.1002/9780470921920.edm061⟩
Book sections hal-01117670v1

Inflammatory response to benzo(a)pyrene, a major environmental contaminant, in primary human macrophages

Normand Podechard , E. Le Ferrec , M. N'Diaye , Lydie Sparfel , David Gilot et al.
11ème Colloque Cytokines de la Société Française d'Immunologie, May 2009, Le Croisic, France
Conference papers hal-00674286v1

Induction of intracellular calcium concentration by environmental benzo(a)pyrene involves a β2-adrenergic receptor/adenylyl cyclase/Epac-1/inositol 1,4,5-trisphosphate pathway in endothelial cells.

Abdullah Mayati , Nicolas Levoin , Hervé Paris , Monique N'Diaye , Arnaud Courtois et al.
Journal of Biological Chemistry, 2012, 287 (6), pp.4041-52. ⟨10.1074/jbc.M111.319970⟩
Journal articles hal-00682497v1

Combustion Particle-Induced Changes in Calcium Homeostasis A Contributing Factor to Vascular Disease?

Jørn A Holme , Bendik C Brinchmann , E. Le Ferrec , Dominique Lagadic-Gossmann , Johan Øvrevik et al.
Cardiovascular Toxicology, 2019, 19 (3), pp.198-209. ⟨10.1007/s12012-019-09518-9⟩
Journal articles hal-02119175v1

Aryl hydrocarbon receptor- and calcium-dependent induction of the chemokine CCL1 by the environmental contaminant benzo[a]pyrene.

Monique N'Diaye , E. Le Ferrec , Dominique Lagadic-Gossmann , Sébastien Corre , David Gilot et al.
Journal of Biological Chemistry, 2006, 281 (29), pp.19906-15. ⟨10.1074/jbc.M601192200⟩
Journal articles hal-00699622v1
Image document

Organic chemicals from diesel exhaust particles affects intracellular calcium, inflammation and β-adrenoceptors in endothelial cells

Bendik C Brinchmann , E. Le Ferrec , Normand Podechard , Dominique Lagadic-Gossmann , Jørn A Holme et al.
Toxicology Letters, 2019, 302, pp.18-27. ⟨10.1016/j.toxlet.2018.11.009⟩
Journal articles hal-01976471v1

AhR- and c-maf-dependent induction of beta7-integrin expression in human macrophages in response to environmental polycyclic aromatic hydrocarbons.

Patricia Monteiro , David Gilot , E. Le Ferrec , Valérie Lecureur , Monique N'Diaye et al.
Biochemical and Biophysical Research Communications, 2007, 358 (2), pp.442-8. ⟨10.1016/j.bbrc.2007.04.111⟩
Journal articles istex hal-00690296v1
Image document

Evidence of selective activation of aryl hydrocarbon receptor nongenomic calcium signaling by pyrene

Bendik C Brinchmann , E. Le Ferrec , William H Bisson , Normand Podechard , Henrik S Huitfeldt et al.
Biochemical Pharmacology, 2018, 158, pp.1-12. ⟨10.1016/j.bcp.2018.09.023⟩
Journal articles hal-01888873v1
Image document

Protective Action of Ostreococcus tauri and Phaeodactylum tricornutum Extracts towards Benzo[a]Pyrene-Induced Cytotoxicity in Endothelial Cells

Manon Le Goff , Antoine Delbrut , Marie Quinton , Rémi Pradelles , Maelle Bescher et al.
Marine drugs, 2019, 18 (1), ⟨10.3390/md18010003⟩
Journal articles hal-02441226v1

TNFalpha- and NF-kappaB-dependent induction of the chemokine CCL1 in human macrophages exposed to the atherogenic lipoprotein(a).

Monique N'Diaye , E. Le Ferrec , Florian Kronenberg , Hans Dieplinger , Marc Le Vee et al.
Life Sciences, 2009, 84 (13-14), pp.451-7. ⟨10.1016/j.lfs.2009.01.012⟩
Journal articles hal-00673344v1

Aryl hydrocarbon receptor- and c-maf-dependent induction of the integrin beta7 by the environmental contaminant benzo(a)pyrene

P. Monteiro , David Gilot , Monique N'Diaye , Valérie Lecureur , E. Le Ferrec et al.
20ième Anniversaire de la Société de Pharmaco-Toxicologie Cellulaire (SPTC), Mar 2006, Paris, France
Conference papers hal-00699763v1

Identification de nouvelles cibles moléculaires des hydrocarbures aromatiques polycycliques : implications potentielles pour l'analyse de risque

Olivier Fardel , David Gilot , Valérie Lecureur , E. Le Ferrec , Marc Le Vee et al.
Journées Scientifiques de l'AFSSET, Feb 2006, Maisons-Alfort, France
Conference papers hal-00699806v1

Interleukin-8 induction by the environmental contaminant benzo(a)pyrene is aryl hydrocarbon receptor-dependent and leads to lung inflammation.

Normand Podechard , Valérie Lecureur , E. Le Ferrec , Isabelle Guenon , Lydie Sparfel et al.
Toxicology Letters, 2008, 177 (2), pp.130-7. ⟨10.1016/j.toxlet.2008.01.006⟩
Journal articles istex hal-00673238v1

Le récepteur Ah et le facteur de transcription c-maf sont indispensables à l'induction de l'intégrine ß7 par le benzo(a)pyrène

P. Monteiro , David Gilot , Monique N'Diaye , Valérie Lecureur , E. Le Ferrec et al.
Conférence à l'institut Curie, Jun 2006, Orsay, France
Conference papers hal-00699680v1

Polycyclic aromatic hydrocarbons can trigger a hepatocyte release of cytotoxic extracellular vesicles

Nettie van Meteren , Martine Chevanne , Isabelle Gallais , Fabienne Gauffre , Soizic Chevance et al.
Journal of Hepatology, 2019, 70 (1), pp.E811. ⟨10.1016/S0618-8278(19)31622-6⟩
Journal articles hal-02149788v1
Image document

Benzo[a]pyrene-induced DNA damage associated with mutagenesis in primary human activated T lymphocytes

Marie Liamin , Elisa Boutet-Robinet , Emilien L. Jamin , Morgane Fernier , Laure Khoury et al.
Biochemical Pharmacology, 2017, 137, pp.113-124. ⟨10.1016/j.bcp.2017.04.025⟩
Journal articles hal-01560145v1

Extracellular vesicles are involved in polycyclic aromatic hydrocarbon hepatotoxicity

N. van Meteren , D. Gobart , I. Gallais , E. Le Ferrec , D. Lagadic-Gossmann et al.
Toxicology Letters, 2019, 314, pp.S187-S188
Journal articles hal-02303536v1

Analysis of drug transporter expression in human intestinal Caco-2 cells by real-time PCR.

Nathalie Maubon , Marc Le Vee , Lina Fossati , Mathilde Audry , E. Le Ferrec et al.
Fundamental & Clinical Pharmacology, 2007, 21 (6), pp.659-63. ⟨10.1111/j.1472-8206.2007.00550.x⟩
Journal articles istex hal-00690294v1
Image document

Calcium signaling and β2-adrenergic receptors regulate 1-nitropyrene induced CXCL8 responses in BEAS-2B cells.

Abdullah Mayati , E. Le Ferrec , Jørn A Holme , Olivier Fardel , Dominique Lagadic-Gossmann et al.
Toxicology in Vitro, 2014, 28 (6), pp.1153-7. ⟨10.1016/j.tiv.2014.05.012⟩
Journal articles hal-01058607v1

Polycyclic aromatic hydrocarbons can trigger hepatocyte release of extracellular vesicles by various mechanisms of action depending on their affinity for the aryl hydrocarbon receptor

Nettie van Meteren , Dominique Lagadic-Gossmann , Martine Chevanne , Isabelle Gallais , Dimitri Gobart et al.
Toxicological Sciences, 2019, 171 (2), pp.443-462. ⟨10.1093/toxsci/kfz157⟩
Journal articles hal-02280777v1

Toxicologie predictive: les voies du futur

Ph Detilleux , L Vallier , C Legallais , E Leclerc , M Prot J et al.
Congrès de la SPTC - Société de Pharmaco-Toxicologie Cellulaire, May 2010, Paris, France
Conference papers hal-01122677v1

Aryl hydrocarbon receptor-independent up-regulation of intracellular calcium concentration by environmental polycyclic aromatic hydrocarbons in human endothelial HMEC-1 cells.

Abdullah Mayati , Eric Le Ferrec , Dominique Lagadic-Gossmann , Olivier Fardel
Environmental Toxicology, 2011, 27 (9), pp.556-562. ⟨10.1002/tox.20675⟩
Journal articles istex hal-00680889v1
Image document

Microalgal carotenoids and phytosterols regulate biochemical mechanisms involved in human health and disease prevention

Manon Le Goff , E. Le Ferrec , Claire Mayer , Virginie Mimouni , Dominique Lagadic-Gossmann et al.
Biochimie, 2019, 167, pp.106-118. ⟨10.1016/j.biochi.2019.09.012⟩
Journal articles hal-02302332v1

Dioxin-mediated up-regulation of aryl hydrocarbon receptor target genes is dependent on the calcium/calmodulin/CaMKIalpha pathway.

Patricia Monteiro , David Gilot , E. Le Ferrec , Claudine Rauch , Dominique Lagadic-Gossmann et al.
Molecular Pharmacology, 2008, 73 (3), pp.769-77. ⟨10.1124/mol.107.043125⟩
Journal articles hal-00696176v1