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A near-infrared fluorogenic dimer enables background-free imaging of endogenous GPCRs in living mice

Lucie Esteoulle , Francois Daubeuf , Mayeul Collot , Stéphanie Riché , Thierry Durroux , et al.
Chemical Science, 2020, 11 (26), pp.6824-6829. ⟨10.1039/d0sc01018a⟩
Journal articles hal-02922372v1

Convenient Access to Fluorescent Probes by Chemoselective Acylation of Hydrazinopeptides: Application to the Synthesis of the First Far-Red Ligand for Apelin Receptor Imaging

Jean-François Margathe , Xavier Iturrioz , Pierre Regenass , Iuliia Karpenko , Nicolas Humbert , et al.
Chemistry - A European Journal, 2016, 22 (4), pp.1399-1405. ⟨10.1002/chem.201503630⟩
Journal articles istex hal-02153700v1
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Self‐organization Properties of a GPCR‐Binding Peptide with a Fluorinated Tail Studied by Fluorine NMR Spectroscopy

Capucine Jourdain de Muison , Sridevi M. Ramanoudjame , Lucie Esteoulle , Claude Ling , Germain Brou , et al.
ChemBioChem, 2020, 22 (4), pp.657-661. ⟨10.1002/cbic.202000601⟩
Journal articles hal-03090942v1
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Discovery of a Locally and Orally Active CXCL12 Neutraligand (LIT-927) with Anti-inflammatory Effect in a Murine Model of Allergic Airway Hypereosinophilia

Pierre Regenass , Dayana Abboud , François Daubeuf , Christine Lehalle , Patrick Gizzi , et al.
Journal of Medicinal Chemistry, 2018, 61 (17), pp.7671-7686. ⟨10.1021/acs.jmedchem.8b00657⟩
Journal articles hal-03563473v1

Solid-Phase Functionalization of Peptides by an α-Hydrazinoacetyl Group

Dominique Bonnet , Cyrille Grandjean , Pierre Rousselot-Pailley , Pascal Joly , Line Bonnet , et al.
Journal of Organic Chemistry, 2003, 68 (18), pp.7033-7040. ⟨10.1021/jo0343432⟩
Journal articles istex hal-02196953v1
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Exploration of the Orthosteric/Allosteric Interface in Human M1 Muscarinic Receptors by Bitopic Fluorescent Ligands

Sandrine B Daval , Esther Kellenberger , Dominique Bonnet , Valérie Utard , Jean-Luc Galzi , et al.
Molecular Pharmacology, 2013, 84 (1), pp.71-85. ⟨10.1124/mol.113.085670⟩
Journal articles hal-02193988v1
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The EHA Research Roadmap: Normal Hematopoiesis

Thierry Jaffredo , Alessandra Balduini , Anna Bigas , Rosa Bernardi , Dominique Bonnet , et al.
HemaSphere, 2021, 5 (12), pp.e669. ⟨10.1097/hs9.0000000000000669⟩
Journal articles hal-03463225v1

The tetrapeptide acserasplyspro (seraspenide), a hematopoietic inhibitor, may reduce the in vitro toxicity of 3'-deoxythymidine to human hematopoietic progenitors

Catherine Grillon , Dominique Bonnet , Jean‐Yves Mary , Maryse Lenfant , Albert Najman , et al.
STEM CELLS, 1993, 11 (5), pp.455-464. ⟨10.1002/stem.5530110513⟩
Journal articles hal-02114633v1

Chemoselective Acylation of Hydrazinopeptides to Access Fluorescent Probes for Time-Resolved FRET Assays on GPCRs

Sridévi Ramanoudjame , Lucie Esteoulle , Stéphanie Riché , Jean-François Margathe , Thierry Durroux , et al.
G Protein-Coupled Receptor Signaling, pp.137-147, 2019, ⟨10.1007/978-1-4939-9121-1_7⟩
Book sections hal-02366300v1

Involvement of TGFβ pathway in the regulation of α5β1 integrins by caveolin-1 in human glioblastoma

Erika Cosset , Julien Godet , Natacha Entz-Werlé , Eric Guérin , Dominique Guenot , et al.
2ème Colloque Inter-régional Grand-Est de Recherche Translationnelle en Oncologie, ONCOTRANS 2011, Sep 2011, Nancy, France
Conference papers hal-00747894v1
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Fluorescent Derivatives of AC-42 To Probe Bitopic Orthosteric/Allosteric Binding Mechanisms on Muscarinic M1 Receptors

Sandrine B Daval , Céline Valant , Dominique Bonnet , Esther Kellenberger , Marcel Hibert , et al.
Journal of Medicinal Chemistry, 2012, 55 (5), pp.2125-2143. ⟨10.1021/jm201348t⟩
Journal articles hal-02193850v1

Neutralizing endogenous chemokines with small molecules : principles and potential therapeutic applications

Jean-Luc Galzi , Muriel Hachet-Haas , Dominique Bonnet , Francois Daubeuf , Sandra Lecat , et al.
Pharmacology and Therapeutics, 2010, 126 (1), ⟨10.1016/j.pharmthera.2009.12.003⟩
Journal articles hal-02196582v1

Decreased Migration of Dendritic Cells into the Jugular-Nodose Ganglia by the CXCL12 Neutraligand Chalcone 4 in Ovalbumin-Sensitized Asthmatic Mice

Sebastian Heck , Francois Daubeuf , Duc dung Le , Martina Sester , Dominique Bonnet , et al.
Neuroimmunomodulation, 2018, 24 (6), pp.331-340. ⟨10.1159/000487140⟩
Journal articles hal-02366307v1

Catalyst-free thia-Diels-Alder click reaction for the labeling of peptides for imaging applications

Timothé Maujean , Patrice Marchand , Patrick Wagner , Stéphanie Riché , Frédéric Boisson , et al.
Phosphorus, Sulfur, and Silicon and the Related Elements, 2023, 198 (6), pp.532-535. ⟨10.1080/10426507.2023.2165659⟩
Journal articles hal-04195673v1
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Functional Rescue of a Nephrogenic Diabetes Insipidus Causing Mutation in the V2 Vasopressin Receptor by Specific Antagonist and Agonist Pharmacochaperones

Laura Szalai , András Sziráki , László Sándor Erdélyi , Kinga Bernadett Kovács , Miklós Tóth , et al.
Frontiers in Pharmacology, 2022, 13 (79), pp.11151-11154. ⟨10.3389/fphar.2022.811836⟩
Journal articles hal-03827827v1

Structure–Activity Relationship Studies toward the Discovery of Selective Apelin Receptor Agonists

Jean-François Margathe , Xavier Iturrioz , Rodrigo Alvear-Perez , Claire Marsol , Stéphanie Riché , et al.
Journal of Medicinal Chemistry, 2014, 57 (7), pp.2908-2919. ⟨10.1021/jm401789v⟩
Journal articles hal-02153719v1

Comparative Study of the Synthesis and Structural and Physicochemical Properties of Diketopiperazines vs Aza-diketopiperazines

Pierre Regenass , Damien Bosc , Stéphanie Riché , Patrick Gizzi , Marcel Hibert , et al.
Journal of Organic Chemistry, 2017, 82 (6), pp.3239-3244. ⟨10.1021/acs.joc.6b02895⟩
Journal articles hal-02366265v1

From the Promiscuous Asenapine to Potent Fluorescent Ligands Acting at a Series of Aminergic G-Protein-Coupled Receptors

Candide Hounsou , Corinne Baehr , Vincent Gasparik , Doria Alili , Abderazak Belhocine , et al.
Journal of Medicinal Chemistry, 2017, 61 (1), pp.174-188. ⟨10.1021/ACS.JMEDCHEM.7B01220⟩
Journal articles hal-02366277v1
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Nile Red-Based GPCR Ligands as Ultrasensitive Probes of the Local Lipid Microenvironment of the Receptor

Fabien Hanser , Claire Marsol , Christel Valencia , Pascal Villa , Andrey S Klymchenko , et al.
ACS Chemical Biology, 2021, 16 (4), pp.651-660. ⟨10.1021/acschembio.0c00897⟩
Journal articles hal-03437257v1
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Biased agonist pharmacochaperones of the AVP V2 receptor may treat congenital nephrogenic diabetes insipidus.

Frédéric Jean-Alphonse , Sanja Perkovska , Marie-Céline Frantz , Thierry Durroux , Catherine Méjean , et al.
Journal of the American Society of Nephrology, 2009, 20 (10), pp.2190-203. ⟨10.1681/ASN.2008121289⟩
Journal articles inserm-00421838v1

CXCL12 neutraligand chalcone 4 inhibits migration of intraganglionic DC in an OVA-sensitized mouse model for allergic airway inflammation

S Heck , F Daubeuf , Ddd Le , M Sester , Dominique Bonnet , et al.
Congress of the European-Academy-of-Allergy-and-Clinical-Immunology (EAACI), May 2018, Munich, Germany. 73, WILEY, pp.516-516, 2018
Proceedings hal-02368587v1

Discovery of a Locally and Orally Active CXCL12 Neutraligand (LIT-927) with Anti-inflammatory Effect in a Murine Model of Allergic Airway Hypereosinophilia

Pierre Regenass , Dayana Abboud , Francois Daubeuf , Christine Lehalle , Patrick Gizzi , et al.
Journal of Medicinal Chemistry, 2018, 61 (17), pp.7671-7686. ⟨10.1021/ACS.JMEDCHEM.8B00657⟩
Journal articles hal-02366281v1

Fluorocarbon-peptide conjugates (FPC): new concept to increase the metabolic stability of peptides for therapeutic applications

Dominique Bonnet
35th European Peptide Symposium, Aug 2018, Dublin, Ireland. ⟨10.17952/35EPS⟩
Conference papers hal-02366339v1
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An Antedrug of the CXCL12 Neutraligand Blocks Experimental Allergic Asthma without Systemic Effect in Mice

Francois Daubeuf , Muriel Hachet-Haas , Patrick Gizzi , Vincent Gasparik , Dominique Bonnet , et al.
Journal of Biological Chemistry, 2013, 288 (17), pp.11865-11876. ⟨10.1074/jbc.M112.449348⟩
Journal articles hal-02194500v1
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Les mégacristaux de feldspaths alcalins dans les formations porphyroïdes des massifs cristallins externes de Belledonne et des Grandes Rousses ( Alpes françaises). Recherche de leurs origines à partir de leurs microstrucutres et de leur composition.

Dominique Bonnet
Minéralogie. Universite Scientifique et Medicale de Grenoble, 1982. Français. ⟨NNT : ⟩
Theses tel-00563221v1
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Three Cheers for Nitrogen: Aza-DKPs, the Aza Analogues of 2,5-Diketopiperazines

Timothé Maujean , Nicolas Girard , A. Ganesan , Mihaela Gulea , Dominique Bonnet
RSC Advances, 2020, 10 (71), pp.43358-43370. ⟨10.1039/d0ra09457a⟩
Journal articles hal-03441420v1
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Activating the apelin receptor with LIT01-196, a metabolically stable apelin analog, reverses AVP-induced antidiuresis and hyponatremia

Adrien Flahault , Pierre-Emmanuel Girault-Sotias , Mathilde Keck , Rodrigo Alvear-Perez , Nadia de Mota , et al.
Nature Communications, 2021, 12 (1), ⟨10.1038/s41467-020-20560-y⟩
Journal articles hal-03285794v1

Two distinct CXCR4 antagonists mobilize progenitor cells in mice by different mechanisms

Andia Redpath , Moïra François , Suet-Ping Wong , Dominique Bonnet , Sara Rankin
Blood Advances, 2017, 1 (22), pp.1934-1943. ⟨10.1182/BLOODADVANCES.2017006064⟩
Journal articles hal-02366286v1
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Comparative Study of the Synthesis and Structural and Physicochemical Properties of Diketopiperazines vs Aza-diketopiperazines

Pierre Regenass , Damien Bosc , Stéphanie Riché , Patrick Gizzi , Marcel Hibert , et al.
Journal of Organic Chemistry, 2017, 82 (6), pp.3239-3244. ⟨10.1021/acs.joc.6b02895⟩
Journal articles hal-03563479v1

Time-resolved FRET binding assay to investigate hetero-oligomer binding properties: proof of concept with dopamine D1/D3 heterodimer

Candide Hounsou , Jean-François Margathe , Nadia Oueslati , Abderazak Belhocine , Elodie Dupuis , et al.
ACS Chemical Biology, 2015, 10 (2), pp.466--74. ⟨10.1021/cb5007568⟩
Journal articles hal-01950133v1