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CRISPR-Cas9: A revolution in genome editing in rheumatic diseases

Isabelle Duroux-Richard , Carine Giovannangeli , Florence Apparailly
Joint Bone Spine, 2017, 84 (1), pp.1 - 4. ⟨10.1016/j.jbspin.2016.09.012⟩
Journal articles hal-01845048v1
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Unraveling Ewing Sarcoma Tumorigenesis Originating from Patient-Derived Mesenchymal Stem Cells

Anna Sole , Sandrine Grossetête , Maxime Heintzé , Loelia Babin , Sakina Zaïdi et al.
Cancer Research, 2021, 81 (19), pp.4994-5006. ⟨10.1158/0008-5472.CAN-20-3837⟩
Journal articles mnhn-03873854v1
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Chromosomal Translocation Formation Is Sufficient to Produce Fusion Circular RNAs Specific to Patient Tumor Cells

Loelia Babin , Marion Piganeau , Benjamin Renouf , Khadija Lamribet , Cécile Thirant et al.
iScience, 2018, 5, pp.19-29. ⟨10.1016/j.isci.2018.06.007⟩
Journal articles mnhn-02402034v1

Generation of Immunodeficient Rats With Rag1 and Il2rg Gene Deletions and Human Tissue Grafting Models

Séverine Menoret , Laure-Hélène Ouisse , Laurent Tesson , Frédéric Delbos , Delphine Garnier et al.
Transplantation, 2018, 102 (8), pp.1271-1278. ⟨10.1097/TP.0000000000002251⟩
Journal articles mnhn-02402053v1
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Differential Requirements for the RAD51 Paralogs in Genome Repair and Maintenance in Human Cells

Edwige B Garcin , Stéphanie Gon , Meghan Sullivan , Gregory J Brunette , Anne De Cian et al.
PLoS Genetics, 2019, 15 (10), pp.e1008355. ⟨10.1371/journal.pgen.1008355⟩
Journal articles hal-02383639v1

Triplex-forming oligonucleotide-orthophenanthroline conjugates for efficient targeted genome modification.

Fabio Cannata , Erika Brunet , Loïc Perrouault , Victoria Roig , Slimane Ait-Si-Ali et al.
Proceedings of the National Academy of Sciences of the United States of America, 2008, 105 (28), pp.9576-81. ⟨10.1073/pnas.0710433105⟩
Journal articles hal-00408029v1
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Base-editing-mediated dissection of a γ-globin cis-regulatory element for the therapeutic reactivation of fetal hemoglobin expression

Panagiotis Antoniou , Giulia Hardouin , Pierre Martinucci , Giacomo Frati , Tristan Felix et al.
Nature Communications, 2022, 13 (1), pp.6618. ⟨10.1038/s41467-022-34493-1⟩
Journal articles mnhn-03868573v1
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Disease modeling by efficient genome editing using a near PAM-less base editor in vivo

Marion Rosello , Malo Serafini , Luca Mignani , Dario Finazzi , Carine Giovannangeli et al.
Nature Communications, 2022, 13 (1), pp.3435. ⟨10.1038/s41467-022-31172-z⟩
Journal articles mnhn-03868574v2
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Editing a y-globin repressor binding site restores fetal hemoglobin synthesis and corrects the sickle cell disease phenotype

Leslie Weber , Giacomo Frati , Tristan Felix , Giulia Hardouin , Antonio Casini et al.
Science Advances , 2020, 6 (7), pp.eaay9392. ⟨10.1126/sciadv.aay9392⟩
Journal articles mnhn-03100446v1
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Gene targeting in rats using transcription activator-like effector nucleases

Séverine Ménoret , Laurent Tesson , Severine Rémy , Claire Usal , Virginie Thépenier et al.
Methods, 2014, 69 (1), pp.102-107. ⟨10.1016/j.ymeth.2014.02.027⟩
Journal articles inserm-02164327v1
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Efficient gene targeting by homology-directed repair in rat zygotes using TALE nucleases

Séverine Remy , Laurent Tesson , Séverine Ménoret , Claire Usal , Anne de Cian et al.
Genome Research, 2014, 24 (8), pp.1371-1383. ⟨10.1101/gr.171538.113⟩
Journal articles inserm-02164405v1
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Recent Progress in Genome Editing for Gene Therapy Applications: The French Perspective

Mario Amendola , Aurélie Bedel , Ana Buj-Bello , Mathieu Carrara , Jean-Paul Concordet et al.
Human Gene Therapy, 2021, 32 (19-20), pp.1059-1075. ⟨10.1089/hum.2021.191⟩
Journal articles hal-03420183v1
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High doses of CRISPR/Cas9 ribonucleoprotein efficiently induce gene knockout with low mosaicism in the hydrozoan Clytia hemisphaerica through microhomology-mediated deletion

Tsuyoshi R Momose , Anne de Cian , Kogiku Shiba , Kazuo Inaba , Carine Giovannangeli et al.
Scientific Reports, 2018, 8 (1), ⟨10.1038/s41598-018-30188-0⟩
Journal articles hal-02142636v1
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Homology-directed repair in rodent zygotes using Cas9 and TALEN engineered proteins

Séverine Ménoret , Anne de Cian , Laurent Tesson , Séverine Remy , Claire Usal et al.
Scientific Reports, 2015, 5, pp.14410. ⟨10.1038/srep14410⟩
Journal articles hal-01271745v1
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The human DNA ends proteome uncovers an unexpected entanglement of functional pathways

Vivien Berthelot , Gildas Mouta-Cardoso , Nadia Hégarat , François Guillonneau , Jean-Christophe François et al.
Nucleic Acids Research, 2016, 44 (10), pp.4721-4733. ⟨10.1093/nar/gkw121⟩
Journal articles hal-01360132v1

Editing a γ-globin repressor binding site restores fetal hemoglobin synthesis and corrects the sickle cell disease phenotype

Leslie Weber , Giacomo Frati , Tristan Felix , Giulia Hardouin , Antonio Casini et al.
Science Advances , 2020, 6 (7), pp.eaay9392. ⟨10.1126/sciadv.aay9392⟩
Journal articles mnhn-03099960v1

Generation of gene-edited rats by delivery of CRISPR/Cas9 protein and donor DNA into intact zygotes using electroporation

Séverine Remy , Vanessa Chenouard , Laurent Tesson , Claire Usal , Séverine Ménoret et al.
Scientific Reports, 2017, Equipe I, 7 (1), pp.16554. ⟨10.1038/s41598-017-16328-y⟩
Journal articles hal-01832141v1

Genome Editing in Rats Using TALE Nucleases

Laurent Tesson , Severine Remy , Séverine Ménoret , Claire Usal , Reynald Thinard et al.
TALENs. Methods in Molecular Biology, pp.245-259, 2016, ⟨10.1007/978-1-4939-2932-0_18⟩
Book sections inserm-02150568v1
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De novo generation of the NPM-ALK fusion recapitulates the pleiotropic phenotypes of ALK+ ALCL pathogenesis and reveals the ROR2 receptor as target for tumor cells

Loélia Babin , Alice Darchen , Elie Robert , Zakia Aid , Rosalie Borry et al.
Molecular Cancer, 2022, 21 (1), pp.65. ⟨10.1186/s12943-022-01520-0⟩
Journal articles mnhn-03868576v1
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The Xenopus tadpole: an in vivo model to screen drugs favoring remyelination

Abdelkrim Mannioui , Quentin Vauzanges , Jean Baptiste Fini , Esther Henriet , Somya Sekizar et al.
Multiple Sclerosis Journal, 2018, 24 (11), pp.1421 - 1432. ⟨10.1177/1352458517721355⟩
Journal articles hal-01912256v1

Lipid-mediated siRNA delivery down-regulates exogenous gene expression in the mouse brain at picomolar levels.

Zahra Hassani , Gregory F Lemkine , Patrick Erbacher , Karima Palmier , Gladys Alfama et al.
The Journal of Gene Medicine, 2005, 7 (2), pp.198-207. ⟨10.1002/jgm.659⟩
Journal articles istex hal-00181088v1

Genome Editing and Dialogic Responsibility: “What's in a Name?”

Alessandro Blasimme , Ignacio Anegon , Jean-Paul Concordet , John de Vos , Anne Dubart-Kupperschmitt et al.
American Journal of Bioethics, 2015, 15 (12), pp.54 - 57. ⟨10.1080/15265161.2015.1103811⟩
Journal articles hal-01893149v1
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A hybrid CMV-H1 construct improves efficiency of PEI-delivered shRNA in the mouse brain.

Zahra Hassani , Jean-Christophe François , Gladys Alfama , Ghislaine Morvan Dubois , Mathilde Paris et al.
Nucleic Acids Research, 2007, 35 (9), pp.e65. ⟨10.1093/nar/gkm152⟩
Journal articles hal-00179406v1
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Characterization of Dystrophin Deficient Rats: A New Model for Duchenne Muscular Dystrophy

Thibaut Larcher , Aude Lafoux , Laurent Tesson , Severine Remy , Virginie Thepenier et al.
PLoS ONE, 2014, 9 (10), 13 p. ⟨10.1371/journal.pone.0110371⟩
Journal articles hal-01190124v1
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Characterization of Dystrophin Deficient Rats: A New Model for Duchenne Muscular Dystrophy

Thibaut Larcher , Aude Lafoux , Laurent Tesson , Séverine Remy , Virginie Thepenier et al.
PLoS ONE, 2014, 9 (10), pp.e110371. ⟨10.1371/journal.pone.0110371⟩
Journal articles inserm-02164371v1

Flavin Conjugates for Delivery of Peptide Nucleic Acids

Fanny Marlin , Philippe Simon , Stéphanie Bonneau , Patrizia Alberti , Céline Cordier et al.
ChemBioChem, 2012, 13 (17), ⟨10.1002/cbic.201200505⟩
Journal articles istex hal-01244566v1
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Improved Genome Editing Efficiency and Flexibility Using Modified Oligonucleotides with TALEN and CRISPR-Cas9 Nucleases.

Jean-Baptiste Renaud , Charlotte Boix , Marine Charpentier , Anne de Cian , Julien Cochennec et al.
Cell Reports, 2016, 14 (9), pp.2263-72. ⟨10.1016/j.celrep.2016.02.018⟩
Journal articles hal-01371505v1

Unraveling Ewing Sarcoma Tumorigenesis Originating from Patient-Derived Mesenchymal Stem Cells

Carine Giovannangeli , Anna Sole , Sandrine Grossetête , Maxime Heintzé , Loelia Babin et al.
Cancer Research, 2021, 81 (19), pp.4994-5006. ⟨10.1158/0008-5472.CAN-20-3837⟩
Journal articles mnhn-03451898v1