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WNT/β-catenin signalling is activated in aldosterone-producing adenomas and controls aldosterone production

Annabel Berthon , Coralie Drelon , Bruno Ragazzon , Sheerazed Boulkroun , Frédérique Tissier et al.
Human Molecular Genetics, 2014, 23 (4), pp.889-905. ⟨10.1093/hmg/ddt484⟩
Journal articles hal-02108060v1
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Novel Insights into the Genetics and Pathophysiology of Adrenocortical Tumors

Ludivine Drougat , Hanin Omeiri , Lucile Lefevre , Bruno Ragazzon
Frontiers in Endocrinology, 2015, 6, pp.96. ⟨10.3389/fendo.2015.00096⟩
Journal articles inserm-01169814v1
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Growth factor receptor binding protein 14 inhibition triggers insulin-induced mouse hepatocyte proliferation and is associated with hepatocellular carcinoma

Lucille Morzyglod , Michèle Caüzac , Lucie Popineau , Pierre-Damien Denechaud , Lluis Fajas et al.
Hepatology, 2017, 65 (4), pp.1352-1368. ⟨10.1002/hep.28972/suppinfo⟩
Journal articles hal-01606970v1
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Analysis of the Role of Igf2 in Adrenal Tumour Development in Transgenic Mouse Models

Coralie Drelon , Annabel Berthon , Bruno Ragazzon , Frédérique Tissier , Roberto Bandiera et al.
PLoS ONE, 2012, 7 (8), pp.e44171. ⟨10.1371/journal.pone.0044171⟩
Journal articles hal-01922100v1
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Link between steroidogenesis, the cell cycle, and PKA in adrenocortical tumor cells

Marthe Rizk-Rabin , Sabrina Chaoui-Ibadioune , Anna Vaczlavik , Christopher Ribes , Michel Polak et al.
Molecular and Cellular Endocrinology, 2020, 500, ⟨10.1016/j.mce.2019.110636⟩
Journal articles hal-03014038v1

Cullin 3 targets the tumor suppressor gene ARMC5 for ubiquitination and degradation

Isadora Pontes Cavalcante , Anna Vaczlavik , Ludivine Drougat , Claudimara Ferini Pacicco Lotfi , Karine Perlemoine et al.
Endocrine-Related Cancer, 2020, 27 (4), pp.221-230. ⟨10.1530/ERC-19-0502⟩
Journal articles hal-02990622v1

A transgenic mouse line with specific Cre recombinase expression in the adrenal cortex

Sarah Lambert-Langlais , Pierre Val , Samuel Guyot , Bruno Ragazzon , Isabelle Sahut-Barnola et al.
Molecular and Cellular Endocrinology, 2009, 300 (1-2), pp.197-204. ⟨10.1016/j.mce.2008.10.045⟩
Journal articles hal-02366480v1
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novel insights into the genetics and pathophysiology of adrenocortical tumors

Ludivine Drougat , Hanin Omeiri , Lucile Lefèvre , Bruno Ragazzon
EPJdirectC - Articles, 2015, ⟨10.3389/fendo.2015.00096⟩
Journal articles inserm-01247515v1

ARMC5 Mutations in a Large Cohort of Primary Macronodular Adrenal Hyperplasia: Clinical and Functional Consequences

Stéphanie Espiard , Ludivine Drougat , Rossella Libé , Guillaume Assié , Karine Perlemoine et al.
Journal of Clinical Endocrinology and Metabolism, 2015, 100 (6), pp.E926-E935. ⟨10.1210/jc.2014-4204⟩
Journal articles hal-01813998v1

EZH2 is overexpressed in adrenocortical carcinoma and is associated with disease progression

Coralie Drelon , Annabel Berthon , Mickael Mathieu , Bruno Ragazzon , Rork Kuick et al.
Human Molecular Genetics, 2016, 25 (13), pp.ddw136. ⟨10.1093/hmg/ddw136⟩
Journal articles hal-02108050v1

Cushing's Syndrome and Fetal Features Resurgence in Adrenal Cortex–Specific Prkar1a Knockout Mice

Isabelle Sahut-Barnola , Cyrille de Joussineau , Pierre Val , Sarah Lambert-Langlais , Christelle Damon et al.
PLoS Genetics, 2010, 6 (6), ⟨10.1371/journal.pgen.1000980⟩
Journal articles hal-01922134v1

Genomic classification of benign adrenocortical lesions

Simon Faillot , Thomas Foulonneau , Mario Néou , Stéphanie Espiard , Simon Garinet et al.
Endocrine-Related Cancer, 2020, ⟨10.1530/ERC-20-0128⟩
Journal articles hal-03049026v1
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Combined transcriptome studies identify AFF3 as a mediator of the oncogenic effects of β-catenin in adrenocortical carcinoma

Lucile Lefèvre , Hanin Omeiri , Ludivine Drougat , Constanze Hantel , Mathieu Giraud et al.
Oncogenesis, 2015, 4 (7), pp.e161. ⟨10.1038/oncsis.2015.20⟩
Journal articles inserm-01182372v1

Adrenocorticotropin/3′,5′-Cyclic AMP-Mediated Transcription of the Scavenger akr1-b7 Gene in Adrenocortical Cells Is Dependent on Three Functionally Distinct Steroidogenic Factor-1-Responsive Elements

Pierre Val , Christelle Aigueperse , Bruno Ragazzon , Georges Veyssière , Anne-Marie Lefrançois-Martinez et al.
Endocrinology, 2004, 145 (2), pp.508-518. ⟨10.1210/en.2003-1093⟩
Journal articles hal-02366490v1

Lack of the presynaptic RhoGAP protein oligophrenin1 leads to cognitive disabilities through dysregulation of the cAMP/PKA signalling pathway

Malik Khelfaoui , Frédéric Gambino , Xander Houbaert , Bruno Ragazzon , Christian Muller et al.
Philosophical Transactions of the Royal Society B: Biological Sciences, 2014, 369 (1633), pp.20130160. ⟨10.1098/rstb.2013.0160⟩
Journal articles hal-02392406v1
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Cullin 3 targets the tumor suppressor gene ARMC5 for ubiquitination and degradation

Isadora Pontes Cavalcante , Anna Vaczlavik , Ludivine Drougat , Claudimara Ferini , Karine Perlemoine et al.
Endocrine-Related Cancer, 2020
Journal articles hal-03014005v1
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IGF2 promotes growth of adrenocortical carcinoma cells, but its overexpression does not modify phenotypic and molecular features of adrenocortical carcinoma.

Marine Guillaud-Bataille , Bruno Ragazzon , Aurélien de Reyniès , Claire Chevalier , Isabelle Francillard et al.
PLoS ONE, 2014, 9 (8), pp.e103744. ⟨10.1371/journal.pone.0103744⟩
Journal articles inserm-01068039v1
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A kinome siRNA screen identifies HGS as a potential target for liver cancers with oncogenic mutations in CTNNB1

Frédéric Canal , Elodie Anthony , Aurianne Lescure , Elaine del Nery , Jacques Camonis et al.
BMC Cancer, 2015, 15 (1), pp.1020. ⟨10.1186/s12885-015-2037-8⟩
Journal articles inserm-01254133v1
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EZH2 cooperates with E2F1 to stimulate expression of genes involved in adrenocortical carcinoma aggressiveness

Houda Tabbal , Amandine Septier , Mickael Mathieu , Coralie Drelon , Stéphanie Rodriguez et al.
British Journal of Cancer, 2019, 121 (5), pp.384-394. ⟨10.1038/s41416-019-0538-y⟩
Journal articles hal-03060155v1
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Aldo Keto Reductase 1B7 and Prostaglandin F2α Are Regulators of Adrenal Endocrine Functions

Sarah Lambert-Langlais , Jean-Christophe Pointud , Anne-Marie Lefrançois-Martinez , Fanny Volat , Michèle Manin et al.
PLoS ONE, 2009, 4 (10), pp.e7309. ⟨10.1371/journal.pone.0007309⟩
Journal articles hal-02366477v1

MET overexpression and activation favors invasiveness in a model of anaplastic thyroid cancer

Cyril Garcia , Camille Buffet , Laila El Khattabi , Marthe Rizk-Rabin , Karine Perlemoine et al.
Oncotarget, 2019, 10 (23), ⟨10.18632/oncotarget.26798⟩
Journal articles hal-02325867v1

Adrenocorticotropin-Dependent Changes in SF-1/DAX-1 Ratio Influence Steroidogenic Genes Expression in a Novel Model of Glucocorticoid-Producing Adrenocortical Cell Lines Derived from Targeted Tumorigenesis

Bruno Ragazzon , Anne-Marie Lefrançois-Martinez , Pierre Val , Isabelle Sahut-Barnola , Colette Tournaire et al.
Endocrinology, 2006, 147 (4), pp.1805-1818. ⟨10.1210/en.2005-1279⟩
Journal articles hal-02366485v1
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Hormonal and spatial control of SUMOylation in the human and mouse adrenal cortex

Typhanie Dumontet , Isabelle Sahut‐barnola , Damien Dufour , Anne-Marie Lefrançois-Martinez , Annabel Berthon et al.
FASEB Journal, 2019, 33 (9), pp.10218-10230. ⟨10.1096/fj.201900557R⟩
Journal articles hal-03060127v1

Integrated genomic characterization of adrenocortical carcinoma.

Guillaume Assié , Eric Letouzé , Martin Fassnacht , Anne Jouinot , Windy Luscap et al.
Nature Genetics, 2014, 46 (6), pp.607-12. ⟨10.1038/ng.2953⟩
Journal articles hal-01255809v1

PKA regulatory subunit 1A inactivating mutation induces serotonin signaling in primary pigmented nodular adrenal disease

Zakariae Bram , Estelle Louiset , Bruno Ragazzon , Sylvie Renouf , Julien Wils et al.
JCI Insight, 2016, 1 (15), pp.e87958. ⟨10.1172/jci.insight.87958⟩
Journal articles hal-02108040v1

ARMC5 Mutations in Macronodular Adrenal Hyperplasia with Cushing's Syndrome

Guillaume Assié , Rossella Libé , Stéphanie Espiard , Marthe Rizk-Rabin , Anne Guimier et al.
New England Journal of Medicine, 2013, 369 (22), pp.2105-2114. ⟨10.1056/NEJMoa1304603⟩
Journal articles hal-02376105v1
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Contrôle hormonal de la stéroïdogenèse et tumorigenèse cortico-surrénalienne : utilisation de la trangenèse chez la souris pour le développement de nouvelles lignées cellulaires et de modèles animaux de pathologies tumorales par oncogenèse ciblée

Bruno Ragazzon
Biologie du développement. Université Blaise Pascal - Clermont-Ferrand II, 2005. Français. ⟨NNT : 2005CLF21629⟩
Theses tel-00686939v1

8Cl-cAMP modifies the balance between PKAR1 and PKAR2 and modulates the cell cycle, growth and apoptosis in human adrenocortical H295R cells

Zhor Bouizar , Bruno Ragazzon , Lucie Viou , Mariuccia Hortane , Jérôme Bertherat et al.
Journal of Molecular Endocrinology, 2010, 44 (6), pp.331-347. ⟨10.1677/JME-09-0120⟩
Journal articles hal-02376050v1

Novel Grb14-Mediated Cross Talk between Insulin and p62/Nrf2 Pathways Regulates Liver Lipogenesis and Selective Insulin Resistance

Lucie Popineau , Lucille Morzyglod , Nadege Carre , Michele Cauzac , Pascale Bossard et al.
Molecular and Cellular Biology, 2016, 36 (16), pp.2168 - 2181. ⟨10.1128/MCB.00170-16⟩
Journal articles hal-01602453v1
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AXIN deficiency in human and mouse hepatocytes induces hepatocellular carcinoma in the absence of β-catenin activation

Shirley Abitbol , Rajae Dahmani , Cédric Coulouarn , Bruno Ragazzon , Bernhard Mlecnik et al.
Journal of Hepatology, 2018, 68 (6), pp.1203-1213. ⟨10.1016/j.jhep.2017.12.018⟩
Journal articles hal-01807225v2