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Anti-NR1 N-terminal-domain vaccination unmasks the crucial action of tPA on NMDA-receptor-mediated toxicity and spatial memory.

Karim Benchenane , Hervé Castel , Michel Boulouard , Rosemarie Bluthé , Monica Fernandez-Monreal et al.
Journal of Cell Science, 2007, 120 (Pt 4), pp.578-585. ⟨10.1242/jcs.03354⟩
Journal articles hal-00178289v1
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Tissue-type plasminogen activator in the ischemic brain: more than a thrombolytic

Manuel Yepes , Benoit D Roussel , Carine Ali , Denis Vivien
Trends in Neurosciences, 2008, ⟨10.1016/j.tins.2008.09.006⟩
Journal articles inserm-01296642v1
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Normalization of Reverse Transcription Quantitative PCR Data During Ageing in Distinct Cerebral Structures

Geoffrey Bruckert , Denis Vivien , Fabian Docagne , Benoit D Roussel
Molecular Neurobiology, 2016, 53 (3), pp.1540-1550. ⟨10.1007/s12035-015-9114-5⟩
Journal articles inserm-01296960v1

Recombinant Desmodus rotundus salivary plasminogen activator crosses the blood-brain barrier through a low-density lipoprotein receptor-related protein-dependent mechanism without exerting neurotoxic effects

José P. Lopez-Atalaya , Benoit D. Roussel , Carine Ali , Eric Maubert , Karl-Uwe Petersen et al.
Stroke, 2007, p. 1036-1043
Journal articles hal-00543483v1
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Activation of cell surface GRP78 decreases endoplasmic reticulum stress and neuronal death

Morgane D Louessard , Isabelle D Bardou , Eloïse D Lemarchand , Audrey D Thiebaut , Jérôme D Parcq et al.
Cell Death and Differentiation, 2017, 24 (9), pp.1518-1529. ⟨10.1038/cdd.2017.35⟩
Journal articles inserm-01586769v1

Cerebrovascular protection as a possible mechanism for the protective effects of NXY-059 in preclinical models: An in vitro study

Maxime Culot , Caroline Mysiorek , Mila Renftel , Benoit D. Roussel , Yannick Hommet et al.
Brain Research, 2009, 1294, p. 144-152
Journal articles hal-00544037v1
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Tissue-type plasminogen activator rescues neurones from serum deprivation-induced apoptosis through a mechanism independent of its proteolytic activity

Géraldine Liot , Benoit D Roussel , Nathalie Lebeurrier , Karim Benchenane , Denis Vivien et al.
Journal of Neurochemistry, 2006, ⟨10.1111/j.1471-4159.2006.03982.x⟩
Journal articles inserm-01296667v1
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Endoplasmic reticulum dysfunction in neurological disease

Benoit D. Roussel , Antonina J Kruppa , Elena Miranda , Damian C Crowther , David A Lomas et al.
The Lancet Neurology, 2013, 12 (1), pp.105 - 118. ⟨10.1016/S1474-4422(12)70238-7⟩
Journal articles inserm-01296824v1
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Two-Chains Tissue Plasminogen Activator Unifies Met and NMDA Receptor Signalling to Control Neuronal Survival

Elodie Hedou , Sara Douceau , Arnaud Chevilley , Alexandre Varangot , Audrey Thiebaut et al.
International Journal of Molecular Sciences, 2021, 22 (24), pp.13483. ⟨10.3390/ijms222413483⟩
Journal articles inserm-03547069v1

Pituitary adenylate cyclase-activating polypeptide (PACAP) stimulates the expression and the release of tissue plasminogen activator (tPA) in neuronal cells: involvement of tPA in the neuroprotective effect of PACAP.

Emilie Raoult , Benoît Denis Roussel , Magalie Bénard , Thomas Lefebvre , Aurélia Ravni et al.
Journal of Neurochemistry, 2011, 119 (5), pp.920-31. ⟨10.1111/j.1471-4159.2011.07486.x⟩
Journal articles pasteur-00819394v1